Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 40 studies | 42% ± 19% | |
endothelial cell | 30 studies | 38% ± 15% | |
pericyte | 25 studies | 37% ± 13% | |
smooth muscle cell | 23 studies | 39% ± 17% | |
ciliated cell | 17 studies | 46% ± 18% | |
myofibroblast cell | 14 studies | 50% ± 25% | |
connective tissue cell | 13 studies | 39% ± 15% | |
endothelial cell of artery | 11 studies | 29% ± 11% | |
endothelial cell of vascular tree | 11 studies | 36% ± 19% | |
capillary endothelial cell | 10 studies | 21% ± 5% | |
basal cell | 10 studies | 24% ± 5% | |
vein endothelial cell | 9 studies | 30% ± 3% | |
epithelial cell | 8 studies | 35% ± 19% | |
type I pneumocyte | 7 studies | 35% ± 13% | |
mesothelial cell | 7 studies | 43% ± 15% | |
endothelial cell of lymphatic vessel | 6 studies | 29% ± 9% | |
podocyte | 5 studies | 48% ± 18% | |
adventitial cell | 4 studies | 40% ± 15% | |
myoepithelial cell | 4 studies | 43% ± 5% | |
secretory cell | 4 studies | 24% ± 6% | |
progenitor cell | 3 studies | 30% ± 11% | |
chondrocyte | 3 studies | 41% ± 13% | |
parietal epithelial cell | 3 studies | 54% ± 23% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 95% | 21996.49 | 436 / 459 | 95% | 578.92 | 1065 / 1118 |
thymus | 95% | 26517.08 | 620 / 653 | 89% | 594.61 | 539 / 605 |
lung | 95% | 25860.04 | 549 / 578 | 85% | 244.60 | 986 / 1155 |
prostate | 88% | 17893.26 | 216 / 245 | 92% | 390.18 | 462 / 502 |
stomach | 87% | 15857.71 | 312 / 359 | 85% | 245.42 | 243 / 286 |
intestine | 87% | 15565.92 | 843 / 966 | 82% | 213.03 | 431 / 527 |
bladder | 100% | 11730.81 | 21 / 21 | 66% | 181.39 | 332 / 504 |
kidney | 92% | 18981.13 | 82 / 89 | 72% | 212.89 | 652 / 901 |
uterus | 98% | 32408.97 | 166 / 170 | 62% | 197.26 | 285 / 459 |
skin | 87% | 17626.17 | 1573 / 1809 | 62% | 161.98 | 291 / 472 |
esophagus | 72% | 20217.57 | 1044 / 1445 | 75% | 182.88 | 138 / 183 |
pancreas | 42% | 4238.93 | 138 / 328 | 95% | 573.00 | 169 / 178 |
ovary | 52% | 6951.36 | 93 / 180 | 77% | 231.35 | 330 / 430 |
ureter | 0% | 0 | 0 / 0 | 100% | 72.83 | 1 / 1 |
blood vessel | 100% | 74812.36 | 1329 / 1335 | 0% | 0 | 0 / 0 |
spleen | 98% | 36854.30 | 237 / 241 | 0% | 0 | 0 / 0 |
adipose | 97% | 24259.45 | 1165 / 1204 | 0% | 0 | 0 / 0 |
adrenal gland | 49% | 5083.13 | 126 / 258 | 42% | 107.07 | 97 / 230 |
brain | 3% | 214.70 | 79 / 2642 | 73% | 150.32 | 517 / 705 |
liver | 30% | 2870.76 | 67 / 226 | 45% | 93.79 | 181 / 406 |
heart | 67% | 17057.35 | 579 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 51% | 101.39 | 23 / 45 |
muscle | 19% | 1785.47 | 154 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 17% | 30.75 | 5 / 29 |
eye | 0% | 0 | 0 / 0 | 8% | 7.24 | 6 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0001525 | Biological process | angiogenesis |
GO_0030324 | Biological process | lung development |
GO_0008544 | Biological process | epidermis development |
GO_0010629 | Biological process | negative regulation of gene expression |
GO_0051496 | Biological process | positive regulation of stress fiber assembly |
GO_0007160 | Biological process | cell-matrix adhesion |
GO_0046330 | Biological process | positive regulation of JNK cascade |
GO_0007165 | Biological process | signal transduction |
GO_0002062 | Biological process | chondrocyte differentiation |
GO_0035988 | Biological process | chondrocyte proliferation |
GO_0007155 | Biological process | cell adhesion |
GO_0072593 | Biological process | reactive oxygen species metabolic process |
GO_0045597 | Biological process | positive regulation of cell differentiation |
GO_0071897 | Biological process | DNA biosynthetic process |
GO_0007229 | Biological process | integrin-mediated signaling pathway |
GO_0001503 | Biological process | ossification |
GO_0001894 | Biological process | tissue homeostasis |
GO_0001502 | Biological process | cartilage condensation |
GO_0032330 | Biological process | regulation of chondrocyte differentiation |
GO_0070374 | Biological process | positive regulation of ERK1 and ERK2 cascade |
GO_0009611 | Biological process | response to wounding |
GO_0016477 | Biological process | cell migration |
GO_0008543 | Biological process | fibroblast growth factor receptor signaling pathway |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0031012 | Cellular component | extracellular matrix |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0008201 | Molecular function | heparin binding |
GO_0005520 | Molecular function | insulin-like growth factor binding |
GO_0005178 | Molecular function | integrin binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CCN2 |
Protein name | CCN family member 2 (Cellular communication network factor 2) (Connective tissue growth factor) (Hypertrophic chondrocyte-specific protein 24) (Insulin-like growth factor-binding protein 8) (IBP-8) (IGF-binding protein 8) (IGFBP-8) CCN family member 2 (Cellular communication network factor 2) (Connective tissue growth factor) |
Synonyms | CTGF HCS24 IGFBP8 |
Description | FUNCTION: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. . |
Accessions | P29279 ENST00000367976.4 [P29279-1] Q5M8T4 Q6FHL8 |