ERBIN report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0070433Biological processnegative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
GO_0045175Biological processbasal protein localization
GO_0032495Biological processresponse to muramyl dipeptide
GO_0007165Biological processsignal transduction
GO_0071638Biological processnegative regulation of monocyte chemotactic protein-1 production
GO_0007155Biological processcell adhesion
GO_0099072Biological processregulation of postsynaptic membrane neurotransmitter receptor levels
GO_0006605Biological processprotein targeting
GO_0032088Biological processnegative regulation of NF-kappaB transcription factor activity
GO_0071356Biological processcellular response to tumor necrosis factor
GO_0007229Biological processintegrin-mediated signaling pathway
GO_0045104Biological processintermediate filament cytoskeleton organization
GO_0007173Biological processepidermal growth factor receptor signaling pathway
GO_0045197Biological processestablishment or maintenance of epithelial cell apical/basal polarity
GO_0032496Biological processresponse to lipopolysaccharide
GO_0098978Cellular componentglutamatergic synapse
GO_0005886Cellular componentplasma membrane
GO_0031594Cellular componentneuromuscular junction
GO_0016607Cellular componentnuclear speck
GO_0009925Cellular componentbasal plasma membrane
GO_0030056Cellular componenthemidesmosome
GO_0005737Cellular componentcytoplasm
GO_0099572Cellular componentpostsynaptic specialization
GO_0005604Cellular componentbasement membrane
GO_0030054Cellular componentcell junction
GO_0031965Cellular componentnuclear membrane
GO_0016323Cellular componentbasolateral plasma membrane
GO_0005634Cellular componentnucleus
GO_0005200Molecular functionstructural constituent of cytoskeleton
GO_0005102Molecular functionsignaling receptor binding
GO_0005176Molecular functionErbB-2 class receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameERBIN
Protein nameErbb2 interacting protein
Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2)
ERBB2IP protein
Erbb2 interacting protein (cDNA FLJ58745, highly similar to Protein LAP2)
SynonymsKIAA1225
LAP2
ERBB2IP
DescriptionFUNCTION: Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state . Inhibits NOD2-dependent NF-kappa-B signaling and pro-inflammatory cytokine secretion . .

AccessionsA0A8V8TP04
B4DIP2
A0A8V8TPD2
A0A8V8TMM1
ENST00000511297.5 [Q96RT1-9]
ENST00000699010.1
ENST00000284037.10 [Q96RT1-1]
ENST00000699005.1
A0A8V8TN23
ENST00000508515.2 [Q96RT1-7]
ENST00000699002.1
ENST00000416865.6
ENST00000380938.6 [Q96RT1-4]
ENST00000503913.6
ENST00000506030.6 [Q96RT1-8]
Q96RT1
A0A8V8TPC7
Q1RMC9
ENST00000699012.1
A0A8V8TML0
A0A8V8TP09
ENST00000699004.1
A0A8V8TP15
ENST00000699000.1 [Q96RT1-2]
ENST00000699011.1
ENST00000511671.6
A0A8V8TML4
ENST00000699007.1
ENST00000699013.1
ENST00000380943.6 [Q96RT1-2]
ENST00000699006.1
A0A8V8TN18
H0YA04
ENST00000699001.1 [Q96RT1-7]
ENST00000699009.1
A0A8V8TML6
ENST00000699008.1
A0A8V8TN29
ENST00000699003.1