Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 16 studies | 46% ± 21% | |
lung | 9 studies | 30% ± 11% | |
peripheral blood | 5 studies | 28% ± 7% | |
heart | 4 studies | 28% ± 4% | |
kidney | 4 studies | 29% ± 9% | |
eye | 3 studies | 44% ± 24% | |
intestine | 3 studies | 21% ± 5% | |
adipose | 3 studies | 36% ± 7% | |
liver | 3 studies | 35% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4003.47 | 1445 / 1445 | 100% | 35.83 | 183 / 183 |
prostate | 100% | 4614.91 | 245 / 245 | 99% | 35.16 | 499 / 502 |
thymus | 100% | 4969.82 | 653 / 653 | 99% | 37.85 | 601 / 605 |
breast | 100% | 4585.63 | 459 / 459 | 99% | 44.62 | 1110 / 1118 |
lung | 100% | 4432.08 | 577 / 578 | 99% | 30.27 | 1148 / 1155 |
ovary | 100% | 4041.24 | 180 / 180 | 99% | 18.55 | 426 / 430 |
kidney | 100% | 3551.61 | 89 / 89 | 99% | 33.28 | 892 / 901 |
uterus | 100% | 4461.30 | 170 / 170 | 98% | 29.48 | 449 / 459 |
bladder | 100% | 4693.10 | 21 / 21 | 97% | 24.84 | 490 / 504 |
brain | 97% | 7230.65 | 2575 / 2642 | 100% | 56.19 | 703 / 705 |
pancreas | 98% | 2339.49 | 323 / 328 | 98% | 30.26 | 175 / 178 |
intestine | 100% | 5849.32 | 966 / 966 | 96% | 23.55 | 506 / 527 |
stomach | 100% | 3827.24 | 359 / 359 | 96% | 26.14 | 274 / 286 |
liver | 100% | 2990.23 | 226 / 226 | 95% | 19.64 | 385 / 406 |
skin | 100% | 7158.12 | 1808 / 1809 | 95% | 34.74 | 447 / 472 |
adrenal gland | 100% | 3529.03 | 258 / 258 | 90% | 14.32 | 206 / 230 |
lymph node | 0% | 0 | 0 / 0 | 100% | 26.70 | 29 / 29 |
spleen | 100% | 4931.01 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 12.56 | 1 / 1 |
blood vessel | 100% | 4100.33 | 1334 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 4276.88 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 2972.00 | 799 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 32.16 | 44 / 45 |
heart | 93% | 2170.70 | 798 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 86% | 3691.08 | 800 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 84% | 25.31 | 67 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0070433 | Biological process | negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway |
GO_0045175 | Biological process | basal protein localization |
GO_0032495 | Biological process | response to muramyl dipeptide |
GO_0007165 | Biological process | signal transduction |
GO_0071638 | Biological process | negative regulation of monocyte chemotactic protein-1 production |
GO_0007155 | Biological process | cell adhesion |
GO_0099072 | Biological process | regulation of postsynaptic membrane neurotransmitter receptor levels |
GO_0006605 | Biological process | protein targeting |
GO_0032088 | Biological process | negative regulation of NF-kappaB transcription factor activity |
GO_0071356 | Biological process | cellular response to tumor necrosis factor |
GO_0007229 | Biological process | integrin-mediated signaling pathway |
GO_0045104 | Biological process | intermediate filament cytoskeleton organization |
GO_0007173 | Biological process | epidermal growth factor receptor signaling pathway |
GO_0045197 | Biological process | establishment or maintenance of epithelial cell apical/basal polarity |
GO_0032496 | Biological process | response to lipopolysaccharide |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0031594 | Cellular component | neuromuscular junction |
GO_0016607 | Cellular component | nuclear speck |
GO_0009925 | Cellular component | basal plasma membrane |
GO_0030056 | Cellular component | hemidesmosome |
GO_0005737 | Cellular component | cytoplasm |
GO_0099572 | Cellular component | postsynaptic specialization |
GO_0005604 | Cellular component | basement membrane |
GO_0030054 | Cellular component | cell junction |
GO_0031965 | Cellular component | nuclear membrane |
GO_0016323 | Cellular component | basolateral plasma membrane |
GO_0005634 | Cellular component | nucleus |
GO_0005200 | Molecular function | structural constituent of cytoskeleton |
GO_0005102 | Molecular function | signaling receptor binding |
GO_0005176 | Molecular function | ErbB-2 class receptor binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ERBIN |
Protein name | Erbb2 interacting protein Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2) ERBB2IP protein Erbb2 interacting protein (cDNA FLJ58745, highly similar to Protein LAP2) |
Synonyms | KIAA1225 LAP2 ERBB2IP |
Description | FUNCTION: Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state . Inhibits NOD2-dependent NF-kappa-B signaling and pro-inflammatory cytokine secretion . . |
Accessions | A0A8V8TP04 B4DIP2 A0A8V8TPD2 A0A8V8TMM1 ENST00000511297.5 [Q96RT1-9] ENST00000699010.1 ENST00000284037.10 [Q96RT1-1] ENST00000699005.1 A0A8V8TN23 ENST00000508515.2 [Q96RT1-7] ENST00000699002.1 ENST00000416865.6 ENST00000380938.6 [Q96RT1-4] ENST00000503913.6 ENST00000506030.6 [Q96RT1-8] Q96RT1 A0A8V8TPC7 Q1RMC9 ENST00000699012.1 A0A8V8TML0 A0A8V8TP09 ENST00000699004.1 A0A8V8TP15 ENST00000699000.1 [Q96RT1-2] ENST00000699011.1 ENST00000511671.6 A0A8V8TML4 ENST00000699007.1 ENST00000699013.1 ENST00000380943.6 [Q96RT1-2] ENST00000699006.1 A0A8V8TN18 H0YA04 ENST00000699001.1 [Q96RT1-7] ENST00000699009.1 A0A8V8TML6 ENST00000699008.1 A0A8V8TN29 ENST00000699003.1 |