ADAM11 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	5 studies	38% ± 22%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	27% ± 18%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	97%	6881.41	2564 / 2642	97%	11.34	681 / 705
prostate	82%	373.52	201 / 245	82%	1.70	412 / 502
uterus	95%	851.56	161 / 170	46%	2.29	213 / 459
ovary	84%	402.49	152 / 180	47%	1.30	201 / 430
skin	42%	134.54	763 / 1809	66%	5.26	310 / 472
heart	92%	1622.19	795 / 861	0%	0	0 / 0
bladder	57%	209.24	12 / 21	31%	1.00	154 / 504
eye	0%	0	0 / 0	88%	6.38	70 / 80
intestine	64%	400.01	614 / 966	5%	0.14	27 / 527
esophagus	31%	100.00	452 / 1445	26%	0.61	48 / 183
breast	37%	122.26	172 / 459	18%	0.41	205 / 1118
stomach	26%	158.38	93 / 359	9%	0.24	27 / 286
thymus	13%	35.00	82 / 653	18%	0.34	108 / 605
adrenal gland	1%	15.63	3 / 258	28%	0.61	65 / 230
lung	4%	13.52	26 / 578	23%	0.65	262 / 1155
adipose	23%	68.86	275 / 1204	0%	0	0 / 0
kidney	3%	10.26	3 / 89	19%	0.40	172 / 901
blood vessel	17%	54.75	230 / 1335	0%	0	0 / 0
liver	0%	1.22	1 / 226	15%	0.40	62 / 406
tonsil	0%	0	0 / 0	11%	0.23	5 / 45
pancreas	0%	0.87	1 / 328	7%	0.26	12 / 178
lymph node	0%	0	0 / 0	3%	0.09	1 / 29
spleen	2%	7.09	6 / 241	0%	0	0 / 0
muscle	1%	2.69	7 / 803	0%	0	0 / 0
peripheral blood	0%	0.23	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0061367	Biological process	behavioral response to acetic acid induced pain
GO_0045184	Biological process	establishment of protein localization
GO_0007229	Biological process	integrin-mediated signaling pathway
GO_0061368	Biological process	behavioral response to formalin induced pain
GO_0033555	Biological process	multicellular organismal response to stress
GO_0006508	Biological process	proteolysis
GO_0043204	Cellular component	perikaryon
GO_0030424	Cellular component	axon
GO_0042734	Cellular component	presynaptic membrane
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0005886	Cellular component	plasma membrane
GO_0004222	Molecular function	metalloendopeptidase activity
GO_0008237	Molecular function	metallopeptidase activity
GO_0005178	Molecular function	integrin binding

Gene name	ADAM11
Protein name	ADAM metallopeptidase domain 11 Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC) ADAM metallopeptidase domain 11 (cDNA FLJ60626, highly similar to ADAM 11 (A disintegrin and metalloproteinase domain 11))
Synonyms	MDC
Description	FUNCTION: Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Required for localization of the potassium channel subunit proteins KCNA1/KV1.1 and KCNA2/KV1.2 at cerebellar cortex basket cell distal terminals, is thereby involved in ephaptic inhibitory synchronization of Purkinje cell firing and response to stress (By similarity). Plays a role in spatial learning and motor coordination (By similarity). Involved in the nociceptive pain response to chemical-derived stimulation (By similarity). .
Accessions	ENST00000355638.8 K7EKA8 B4DKD2 O75078 ENST00000587773.1 ENST00000535346.5 ENST00000200557.11 [O75078-1] H7BY08

ADAM11 report