IQGAP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_1903479Biological processmitotic actomyosin contractile ring assembly actin filament organization
GO_0070493Biological processthrombin-activated receptor signaling pathway
GO_0034314Biological processArp2/3 complex-mediated actin nucleation
GO_0032956Biological processregulation of actin cytoskeleton organization
GO_0005902Cellular componentmicrovillus
GO_0030667Cellular componentsecretory granule membrane
GO_0005886Cellular componentplasma membrane
GO_0070062Cellular componentextracellular exosome
GO_0009986Cellular componentcell surface
GO_0030175Cellular componentfilopodium
GO_0015629Cellular componentactin cytoskeleton
GO_0005829Cellular componentcytosol
GO_0005938Cellular componentcell cortex
GO_0005737Cellular componentcytoplasm
GO_0030027Cellular componentlamellipodium
GO_0005547Molecular functionphosphatidylinositol-3,4,5-trisphosphate binding
GO_0005095Molecular functionGTPase inhibitor activity
GO_0051015Molecular functionactin filament binding
GO_0071933Molecular functionArp2/3 complex binding
GO_0031267Molecular functionsmall GTPase binding
GO_0005096Molecular functionGTPase activator activity
GO_0005516Molecular functioncalmodulin binding
GO_0003779Molecular functionactin binding

IV. Literature review

[source]
Gene nameIQGAP2
Protein nameIQ motif containing GTPase activating protein 2
Ras GTPase-activating-like protein IQGAP2
Synonyms
DescriptionFUNCTION: Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.

AccessionsE9PDT6
ENST00000504254.5
F5H7S7
D6R939
H0YA28
ENST00000379730.7
ENST00000509074.5
ENST00000396234.7 [Q13576-2]
ENST00000514350.5
ENST00000274364.11 [Q13576-1]
D6R999
A0A8I5KRM2
ENST00000502745.5 [Q13576-3]
ENST00000514001.5
D6RDK8
Q13576
ENST00000685564.1
ENST00000504477.5