Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| smooth muscle cell | 31 studies | 34% ± 17% | |
| fibroblast | 30 studies | 29% ± 11% | |
| pericyte | 23 studies | 29% ± 9% | |
| endothelial cell | 20 studies | 28% ± 11% | |
| ciliated cell | 19 studies | 41% ± 12% | |
| astrocyte | 17 studies | 35% ± 16% | |
| oligodendrocyte | 16 studies | 34% ± 14% | |
| oligodendrocyte precursor cell | 16 studies | 39% ± 17% | |
| basal cell | 14 studies | 26% ± 8% | |
| myofibroblast cell | 12 studies | 34% ± 13% | |
| GABAergic neuron | 11 studies | 50% ± 21% | |
| glutamatergic neuron | 11 studies | 43% ± 24% | |
| epithelial cell | 9 studies | 31% ± 20% | |
| connective tissue cell | 8 studies | 31% ± 15% | |
| neuron | 8 studies | 46% ± 19% | |
| abnormal cell | 7 studies | 31% ± 10% | |
| interneuron | 7 studies | 53% ± 19% | |
| club cell | 6 studies | 27% ± 10% | |
| retinal cone cell | 6 studies | 41% ± 24% | |
| endothelial cell of vascular tree | 6 studies | 24% ± 10% | |
| adipocyte | 5 studies | 29% ± 16% | |
| cardiac muscle cell | 5 studies | 39% ± 7% | |
| respiratory goblet cell | 5 studies | 29% ± 13% | |
| type II pneumocyte | 5 studies | 20% ± 2% | |
| retinal ganglion cell | 4 studies | 38% ± 9% | |
| capillary endothelial cell | 4 studies | 23% ± 5% | |
| Mueller cell | 4 studies | 22% ± 8% | |
| luminal hormone-sensing cell of mammary gland | 4 studies | 26% ± 9% | |
| muscle cell | 4 studies | 42% ± 14% | |
| neural crest cell | 3 studies | 25% ± 2% | |
| GABAergic interneuron | 3 studies | 45% ± 6% | |
| granule cell | 3 studies | 30% ± 5% | |
| progenitor cell | 3 studies | 34% ± 10% | |
| brush cell | 3 studies | 31% ± 14% | |
| retina horizontal cell | 3 studies | 29% ± 19% | |
| endothelial cell of artery | 3 studies | 20% ± 4% | |
| vein endothelial cell | 3 studies | 26% ± 14% | |
| pancreatic ductal cell | 3 studies | 44% ± 21% | |
| neural progenitor cell | 3 studies | 49% ± 9% | |
| ependymal cell | 3 studies | 51% ± 13% | |
| enteroendocrine cell | 3 studies | 22% ± 5% | |
| adventitial cell | 3 studies | 25% ± 6% | |
| chondrocyte | 3 studies | 25% ± 7% | |
| transit amplifying cell | 3 studies | 25% ± 8% | |
| luminal cell of prostate epithelium | 3 studies | 26% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 6560.53 | 458 / 459 | 100% | 72.65 | 1113 / 1118 |
| prostate | 100% | 9053.47 | 245 / 245 | 98% | 30.31 | 493 / 502 |
| brain | 99% | 4416.26 | 2605 / 2642 | 100% | 56.18 | 702 / 705 |
| lung | 100% | 7685.49 | 576 / 578 | 98% | 39.56 | 1135 / 1155 |
| ovary | 100% | 8006.03 | 180 / 180 | 97% | 28.83 | 419 / 430 |
| uterus | 100% | 8205.90 | 170 / 170 | 95% | 35.56 | 438 / 459 |
| esophagus | 98% | 7891.20 | 1411 / 1445 | 97% | 49.29 | 178 / 183 |
| bladder | 100% | 14647.48 | 21 / 21 | 92% | 26.58 | 463 / 504 |
| stomach | 100% | 8792.36 | 359 / 359 | 91% | 23.94 | 259 / 286 |
| pancreas | 95% | 2925.00 | 310 / 328 | 92% | 19.96 | 164 / 178 |
| skin | 100% | 6830.06 | 1801 / 1809 | 85% | 30.21 | 400 / 472 |
| intestine | 95% | 9540.02 | 918 / 966 | 87% | 18.68 | 461 / 527 |
| thymus | 98% | 3600.81 | 640 / 653 | 81% | 14.68 | 489 / 605 |
| adrenal gland | 100% | 6781.41 | 258 / 258 | 50% | 7.74 | 115 / 230 |
| kidney | 62% | 1614.45 | 55 / 89 | 70% | 11.52 | 629 / 901 |
| adipose | 100% | 6291.25 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 18093.74 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.91 | 1 / 1 |
| spleen | 99% | 4602.50 | 239 / 241 | 0% | 0 | 0 / 0 |
| muscle | 99% | 5446.97 | 796 / 803 | 0% | 0 | 0 / 0 |
| heart | 93% | 5440.18 | 805 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 24.72 | 41 / 45 |
| liver | 23% | 443.89 | 53 / 226 | 66% | 16.94 | 267 / 406 |
| eye | 0% | 0 | 0 / 0 | 23% | 2.63 | 18 / 80 |
| peripheral blood | 0% | 1.51 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0008154 | Biological process | actin polymerization or depolymerization |
| GO_0070358 | Biological process | actin polymerization-dependent cell motility |
| GO_0007411 | Biological process | axon guidance |
| GO_0030054 | Cellular component | cell junction |
| GO_0030175 | Cellular component | filopodium |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0005829 | Cellular component | cytosol |
| GO_0030027 | Cellular component | lamellipodium |
| GO_0045202 | Cellular component | synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005925 | Cellular component | focal adhesion |
| GO_0017124 | Molecular function | SH3 domain binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003779 | Molecular function | actin binding |
| GO_0050699 | Molecular function | WW domain binding |
| GO_0005522 | Molecular function | profilin binding |
| Gene name | ENAH |
| Protein name | Protein enabled homolog ENAH actin regulator Mammalian enabled variant 11a Mammalian enabled variant pan |
| Synonyms | MENA |
| Description | FUNCTION: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation (By similarity). . |
| Accessions | A0A075B6E5 ENST00000366844.7 [Q8N8S7-1] A0A0U1RQP7 ENST00000497899.6 Q8N8S7 ENST00000284563.7 ENST00000366843.7 [Q8N8S7-2] A0A097PIC4 A0A0U1RRM6 ENST00000696609.1 ENST00000635051.1 A0A8Q3WLE0 A0A097PID1 |