ENAH report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008154Biological processactin polymerization or depolymerization
GO_0070358Biological processactin polymerization-dependent cell motility
GO_0007411Biological processaxon guidance
GO_0030054Cellular componentcell junction
GO_0030175Cellular componentfilopodium
GO_0005856Cellular componentcytoskeleton
GO_0005829Cellular componentcytosol
GO_0030027Cellular componentlamellipodium
GO_0045202Cellular componentsynapse
GO_0005886Cellular componentplasma membrane
GO_0005925Cellular componentfocal adhesion
GO_0017124Molecular functionSH3 domain binding
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding
GO_0050699Molecular functionWW domain binding
GO_0005522Molecular functionprofilin binding

IV. Literature review

[source]
Gene nameENAH
Protein nameProtein enabled homolog
ENAH actin regulator
Mammalian enabled variant 11a
Mammalian enabled variant pan
SynonymsMENA
DescriptionFUNCTION: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation (By similarity). .

AccessionsA0A075B6E5
ENST00000366844.7 [Q8N8S7-1]
A0A0U1RQP7
ENST00000497899.6
Q8N8S7
ENST00000284563.7
ENST00000366843.7 [Q8N8S7-2]
A0A097PIC4
A0A0U1RRM6
ENST00000696609.1
ENST00000635051.1
A0A8Q3WLE0
A0A097PID1