Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| pericyte | 37 studies | 62% ± 25% | |
| smooth muscle cell | 34 studies | 81% ± 18% | |
| fibroblast | 30 studies | 36% ± 17% | |
| myofibroblast cell | 16 studies | 77% ± 16% | |
| connective tissue cell | 12 studies | 43% ± 26% | |
| endothelial cell | 7 studies | 33% ± 10% | |
| myoepithelial cell | 4 studies | 85% ± 8% | |
| regulatory T cell | 3 studies | 19% ± 2% | |
| muscle cell | 3 studies | 86% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 82% | 71908.42 | 201 / 245 | 99% | 456.99 | 497 / 502 |
| breast | 78% | 33000.47 | 359 / 459 | 94% | 164.02 | 1047 / 1118 |
| bladder | 95% | 106852.00 | 20 / 21 | 75% | 128.40 | 377 / 504 |
| intestine | 76% | 61007.97 | 734 / 966 | 86% | 127.97 | 451 / 527 |
| esophagus | 77% | 111042.16 | 1109 / 1445 | 74% | 101.63 | 136 / 183 |
| uterus | 98% | 190891.89 | 167 / 170 | 53% | 219.18 | 241 / 459 |
| lung | 68% | 23730.11 | 394 / 578 | 82% | 115.47 | 952 / 1155 |
| stomach | 50% | 42826.74 | 180 / 359 | 91% | 192.67 | 259 / 286 |
| ovary | 44% | 23822.28 | 80 / 180 | 63% | 82.90 | 270 / 430 |
| blood vessel | 100% | 305240.34 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| pancreas | 0% | 0 | 0 / 328 | 95% | 240.89 | 169 / 178 |
| thymus | 22% | 6937.69 | 141 / 653 | 71% | 47.85 | 427 / 605 |
| kidney | 18% | 6157.73 | 16 / 89 | 69% | 148.99 | 620 / 901 |
| skin | 13% | 3655.28 | 242 / 1809 | 57% | 38.92 | 267 / 472 |
| adrenal gland | 7% | 1583.48 | 17 / 258 | 59% | 69.66 | 136 / 230 |
| adipose | 64% | 30511.13 | 765 / 1204 | 0% | 0 | 0 / 0 |
| liver | 2% | 536.71 | 4 / 226 | 50% | 34.97 | 202 / 406 |
| eye | 0% | 0 | 0 / 0 | 48% | 23.65 | 38 / 80 |
| heart | 36% | 13630.79 | 312 / 861 | 0% | 0 | 0 / 0 |
| spleen | 35% | 11027.22 | 84 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 34% | 15.12 | 10 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 33% | 23.95 | 15 / 45 |
| brain | 0% | 133.65 | 9 / 2642 | 24% | 17.98 | 169 / 705 |
| muscle | 3% | 880.76 | 24 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0061870 | Biological process | positive regulation of hepatic stellate cell migration |
| GO_0072144 | Biological process | glomerular mesangial cell development |
| GO_0071560 | Biological process | cellular response to transforming growth factor beta stimulus |
| GO_0008217 | Biological process | regulation of blood pressure |
| GO_0009615 | Biological process | response to virus |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0072051 | Biological process | juxtaglomerular apparatus development |
| GO_0014829 | Biological process | vascular associated smooth muscle contraction |
| GO_0061874 | Biological process | positive regulation of hepatic stellate cell contraction |
| GO_2000491 | Biological process | positive regulation of hepatic stellate cell activation |
| GO_0070374 | Biological process | positive regulation of ERK1 and ERK2 cascade |
| GO_0090131 | Biological process | mesenchyme migration |
| GO_0005615 | Cellular component | extracellular space |
| GO_0031514 | Cellular component | motile cilium |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0030485 | Cellular component | smooth muscle contractile fiber |
| GO_0030175 | Cellular component | filopodium |
| GO_0001725 | Cellular component | stress fiber |
| GO_0015629 | Cellular component | actin cytoskeleton |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0044297 | Cellular component | cell body |
| GO_0005604 | Cellular component | basement membrane |
| GO_0030027 | Cellular component | lamellipodium |
| GO_0016787 | Molecular function | hydrolase activity |
| GO_0019901 | Molecular function | protein kinase binding |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | ACTA2 |
| Protein name | Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form] Actin, aortic smooth muscle (Alpha-actin-2) |
| Synonyms | ACTVS ACTSA GIG46 |
| Description | FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. . FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. . FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. . FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. . |
| Accessions | ENST00000415557.2 ENST00000458159.5 P62736 ENST00000458159.6 F6QUT6 ENST00000224784.10 Q13707 F6UVQ4 D2JYH4 ENST00000415557.1 |
