Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 24 studies | 82% ± 19% | |
endothelial cell of lymphatic vessel | 19 studies | 45% ± 18% | |
endothelial cell | 17 studies | 39% ± 20% | |
oligodendrocyte precursor cell | 16 studies | 84% ± 12% | |
glutamatergic neuron | 13 studies | 90% ± 10% | |
GABAergic neuron | 11 studies | 78% ± 16% | |
oligodendrocyte | 11 studies | 34% ± 19% | |
microglial cell | 11 studies | 36% ± 16% | |
type I pneumocyte | 10 studies | 48% ± 20% | |
interneuron | 8 studies | 80% ± 11% | |
amacrine cell | 8 studies | 66% ± 21% | |
neuron | 6 studies | 63% ± 21% | |
retinal ganglion cell | 6 studies | 45% ± 19% | |
mesothelial cell | 6 studies | 34% ± 7% | |
retina horizontal cell | 6 studies | 58% ± 18% | |
Mueller cell | 6 studies | 89% ± 10% | |
smooth muscle cell | 5 studies | 38% ± 13% | |
retinal bipolar neuron | 5 studies | 56% ± 15% | |
OFF-bipolar cell | 5 studies | 46% ± 25% | |
retinal cone cell | 5 studies | 34% ± 21% | |
macrophage | 4 studies | 38% ± 18% | |
epithelial cell | 4 studies | 64% ± 14% | |
granule cell | 4 studies | 85% ± 8% | |
ON-bipolar cell | 4 studies | 47% ± 22% | |
GABAergic amacrine cell | 4 studies | 70% ± 22% | |
glycinergic amacrine cell | 4 studies | 63% ± 20% | |
retinal pigment epithelial cell | 4 studies | 80% ± 17% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 75% ± 1% | |
GABAergic interneuron | 3 studies | 80% ± 7% | |
rod bipolar cell | 3 studies | 54% ± 7% | |
neural progenitor cell | 3 studies | 90% ± 6% | |
ependymal cell | 3 studies | 78% ± 6% | |
type II pneumocyte | 3 studies | 30% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 98% | 39777.82 | 2602 / 2642 | 100% | 523.96 | 705 / 705 |
esophagus | 35% | 1799.69 | 505 / 1445 | 16% | 1.41 | 29 / 183 |
intestine | 30% | 1387.91 | 293 / 966 | 6% | 0.27 | 29 / 527 |
thymus | 1% | 41.66 | 9 / 653 | 34% | 2.16 | 203 / 605 |
prostate | 2% | 62.40 | 4 / 245 | 31% | 1.62 | 156 / 502 |
kidney | 0% | 0 | 0 / 89 | 29% | 2.88 | 259 / 901 |
lymph node | 0% | 0 | 0 / 0 | 28% | 4.56 | 8 / 29 |
ovary | 2% | 60.22 | 3 / 180 | 20% | 1.20 | 85 / 430 |
pancreas | 0% | 0 | 0 / 328 | 20% | 1.14 | 35 / 178 |
adrenal gland | 0% | 41.25 | 1 / 258 | 15% | 1.39 | 34 / 230 |
lung | 2% | 61.98 | 11 / 578 | 9% | 0.70 | 108 / 1155 |
eye | 0% | 0 | 0 / 0 | 11% | 1.33 | 9 / 80 |
breast | 0% | 0 | 0 / 459 | 9% | 2.87 | 97 / 1118 |
stomach | 0% | 0 | 0 / 359 | 6% | 0.20 | 17 / 286 |
uterus | 0% | 0 | 0 / 170 | 6% | 0.34 | 27 / 459 |
skin | 0% | 0 | 0 / 1809 | 5% | 1.02 | 24 / 472 |
liver | 0% | 0 | 0 / 226 | 5% | 0.25 | 19 / 406 |
bladder | 0% | 0 | 0 / 21 | 3% | 0.16 | 17 / 504 |
spleen | 1% | 24.90 | 2 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 1% | 33.89 | 11 / 1335 | 0% | 0 | 0 / 0 |
adipose | 0% | 3.34 | 1 / 1204 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0009617 | Biological process | response to bacterium |
GO_0031175 | Biological process | neuron projection development |
GO_0003407 | Biological process | neural retina development |
GO_0001764 | Biological process | neuron migration |
GO_0048812 | Biological process | neuron projection morphogenesis |
GO_0050807 | Biological process | regulation of synapse organization |
GO_0051491 | Biological process | positive regulation of filopodium assembly |
GO_0007416 | Biological process | synapse assembly |
GO_0048863 | Biological process | stem cell differentiation |
GO_0070588 | Biological process | calcium ion transmembrane transport |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0043197 | Cellular component | dendritic spine |
GO_0048787 | Cellular component | presynaptic active zone membrane |
GO_1903561 | Cellular component | extracellular vesicle |
GO_0070062 | Cellular component | extracellular exosome |
GO_0043025 | Cellular component | neuronal cell body |
GO_0043005 | Cellular component | neuron projection |
GO_0030175 | Cellular component | filopodium |
GO_0044295 | Cellular component | axonal growth cone |
GO_0098688 | Cellular component | parallel fiber to Purkinje cell synapse |
GO_0005515 | Molecular function | protein binding |
GO_0005262 | Molecular function | calcium channel activity |
Gene name | GPM6A |
Protein name | Neuronal membrane glycoprotein M6-a Glycoprotein M6A Neuronal membrane glycoprotein M6-a (M6a) |
Synonyms | M6A |
Description | FUNCTION: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. . |
Accessions | ENST00000505375.5 ENST00000509865.5 D6RFZ3 D6RD95 ENST00000503563.1 ENST00000502754.5 D6R9T7 ENST00000503397.5 ENST00000506894.5 [P51674-3] ENST00000507520.5 ENST00000513667.5 ENST00000280187.11 [P51674-1] ENST00000512897.5 D6RBM6 ENST00000505304.1 D6RBH3 A0A1D5RMS2 D6RD71 D6RIF4 ENST00000393658.7 [P51674-1] D6RDV7 Q49AH3 ENST00000507540.1 Q86YB0 ENST00000512509.5 ENST00000513365.1 ENST00000512610.5 D6RB41 ENST00000505561.5 P51674 D6RAE4 D6R9D2 D6RFY0 ENST00000515090.5 [P51674-2] D6REJ8 |