FARP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1905606Biological processregulation of presynapse assembly
GO_0098942Biological processretrograde trans-synaptic signaling by trans-synaptic protein complex
GO_0048813Biological processdendrite morphogenesis
GO_0007167Biological processenzyme-linked receptor protein signaling pathway
GO_0098974Biological processpostsynaptic actin cytoskeleton organization
GO_0016601Biological processRac protein signal transduction
GO_1904395Biological processpositive regulation of skeletal muscle acetylcholine-gated channel clustering
GO_0007416Biological processsynapse assembly
GO_0098978Cellular componentglutamatergic synapse
GO_0005856Cellular componentcytoskeleton
GO_0043197Cellular componentdendritic spine
GO_0009898Cellular componentcytoplasmic side of plasma membrane
GO_0098890Cellular componentextrinsic component of postsynaptic membrane
GO_0030425Cellular componentdendrite
GO_0030175Cellular componentfilopodium
GO_0005829Cellular componentcytosol
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0031267Molecular functionsmall GTPase binding
GO_0008092Molecular functioncytoskeletal protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameFARP1
Protein nameFERM, ARHGEF and pleckstrin domain-containing protein 1 (Chondrocyte-derived ezrin-like protein) (FERM, RhoGEF and pleckstrin domain-containing protein 1) (Pleckstrin homology domain-containing family C member 2) (PH domain-containing family C member 2)
FERM, ARHGEF and pleckstrin domain-containing protein 1 (FERM, RhoGEF and pleckstrin domain-containing protein 1)
FERM, ARH/RhoGEF and pleckstrin domain protein 1
SynonymsCDEP
hCG_1811328
PLEKHC2
DescriptionFUNCTION: Functions as a guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity). .

AccessionsENST00000627049.2
ENST00000595437.5
ENST00000423063.2
M0R262
ENST00000598389.5
M0QXT1
Q9Y4F1
ENST00000601009.1
ENST00000376581.9 [Q9Y4F1-3]
ENST00000596256.1
A0A2X0TVY0
H0Y783
ENST00000319562.11 [Q9Y4F1-1]
ENST00000596580.2
C9JME2
A0A1B0GV68
M0QYB0