Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 26 studies | 36% ± 19% | |
endothelial cell of lymphatic vessel | 17 studies | 43% ± 16% | |
fibroblast | 12 studies | 32% ± 12% | |
macrophage | 10 studies | 38% ± 18% | |
dendritic cell | 10 studies | 61% ± 22% | |
oligodendrocyte | 10 studies | 25% ± 7% | |
connective tissue cell | 9 studies | 42% ± 18% | |
basal cell | 8 studies | 20% ± 4% | |
capillary endothelial cell | 8 studies | 35% ± 26% | |
neuron | 7 studies | 45% ± 28% | |
microglial cell | 7 studies | 30% ± 13% | |
vein endothelial cell | 6 studies | 40% ± 27% | |
myeloid cell | 5 studies | 22% ± 3% | |
glomerular endothelial cell | 4 studies | 28% ± 10% | |
mesothelial cell | 4 studies | 28% ± 14% | |
pericyte | 4 studies | 25% ± 10% | |
erythroblast | 4 studies | 24% ± 6% | |
glutamatergic neuron | 4 studies | 31% ± 6% | |
abnormal cell | 3 studies | 33% ± 7% | |
neural crest cell | 3 studies | 60% ± 23% | |
hematopoietic stem cell | 3 studies | 19% ± 5% | |
epithelial cell | 3 studies | 26% ± 3% | |
myofibroblast cell | 3 studies | 31% ± 5% | |
GABAergic neuron | 3 studies | 24% ± 3% | |
oligodendrocyte precursor cell | 3 studies | 39% ± 18% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 40% ± 15% | |
interneuron | 3 studies | 20% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 99% | 7461.61 | 2610 / 2642 | 98% | 261.43 | 692 / 705 |
ovary | 100% | 6599.14 | 180 / 180 | 86% | 146.96 | 369 / 430 |
uterus | 94% | 2552.81 | 159 / 170 | 86% | 279.66 | 394 / 459 |
skin | 100% | 11046.27 | 1803 / 1809 | 77% | 226.52 | 362 / 472 |
lung | 96% | 3897.49 | 557 / 578 | 80% | 229.92 | 920 / 1155 |
bladder | 86% | 2672.76 | 18 / 21 | 76% | 209.27 | 385 / 504 |
esophagus | 73% | 4026.70 | 1058 / 1445 | 86% | 466.34 | 158 / 183 |
breast | 93% | 3538.85 | 429 / 459 | 65% | 74.27 | 727 / 1118 |
adrenal gland | 100% | 5656.47 | 258 / 258 | 52% | 115.36 | 119 / 230 |
thymus | 98% | 3853.96 | 640 / 653 | 51% | 36.20 | 310 / 605 |
kidney | 80% | 1953.74 | 71 / 89 | 66% | 68.71 | 593 / 901 |
intestine | 65% | 1441.45 | 632 / 966 | 47% | 63.47 | 250 / 527 |
spleen | 100% | 8179.12 | 241 / 241 | 0% | 0 | 0 / 0 |
adipose | 95% | 3679.69 | 1139 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 364.15 | 42 / 45 |
eye | 0% | 0 | 0 / 0 | 93% | 144.46 | 74 / 80 |
pancreas | 6% | 103.02 | 19 / 328 | 83% | 129.79 | 148 / 178 |
stomach | 33% | 632.82 | 119 / 359 | 49% | 60.64 | 141 / 286 |
blood vessel | 66% | 1628.80 | 879 / 1335 | 0% | 0 | 0 / 0 |
prostate | 62% | 1337.60 | 152 / 245 | 1% | 0.64 | 6 / 502 |
heart | 54% | 1131.70 | 462 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 52% | 86.31 | 15 / 29 |
liver | 22% | 442.76 | 50 / 226 | 17% | 23.83 | 71 / 406 |
peripheral blood | 20% | 5288.34 | 182 / 929 | 0% | 0 | 0 / 0 |
muscle | 4% | 52.71 | 29 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0071803 | Biological process | positive regulation of podosome assembly |
GO_0048870 | Biological process | cell motility |
GO_0007043 | Biological process | cell-cell junction assembly |
GO_0090091 | Biological process | positive regulation of extracellular matrix disassembly |
GO_0007163 | Biological process | establishment or maintenance of cell polarity |
GO_0010592 | Biological process | positive regulation of lamellipodium assembly |
GO_0032534 | Biological process | regulation of microvillus assembly |
GO_0051017 | Biological process | actin filament bundle assembly |
GO_0035089 | Biological process | establishment of apical/basal cell polarity |
GO_0030036 | Biological process | actin cytoskeleton organization |
GO_0051491 | Biological process | positive regulation of filopodium assembly |
GO_0030035 | Biological process | microspike assembly |
GO_0030046 | Biological process | parallel actin filament bundle assembly |
GO_0016477 | Biological process | cell migration |
GO_0032956 | Biological process | regulation of actin cytoskeleton organization |
GO_0001726 | Cellular component | ruffle |
GO_0005902 | Cellular component | microvillus |
GO_0005856 | Cellular component | cytoskeleton |
GO_0070062 | Cellular component | extracellular exosome |
GO_0002102 | Cellular component | podosome |
GO_0005911 | Cellular component | cell-cell junction |
GO_0044393 | Cellular component | microspike |
GO_0030175 | Cellular component | filopodium |
GO_0001725 | Cellular component | stress fiber |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0005938 | Cellular component | cell cortex |
GO_0030426 | Cellular component | growth cone |
GO_0031253 | Cellular component | cell projection membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0030027 | Cellular component | lamellipodium |
GO_0045296 | Molecular function | cadherin binding |
GO_0051015 | Molecular function | actin filament binding |
GO_0003779 | Molecular function | actin binding |
GO_0030674 | Molecular function | protein-macromolecule adaptor activity |
GO_0003723 | Molecular function | RNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | FSCN1 |
Protein name | Fascin actin-bundling protein 1 Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55) |
Synonyms | FAN1 HSN SNL |
Description | FUNCTION: Actin-binding protein that contains 2 major actin binding sites . Organizes filamentous actin into parallel bundles . Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers . Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration . Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF . . |
Accessions | C9JFC0 ENST00000382361.8 Q16658 ENST00000447103.5 ENST00000405801.2 C9JPH9 A0A0A0MSB2 ENST00000444748.5 |