TWF2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0071300Biological processcellular response to retinoic acid
GO_0030837Biological processnegative regulation of actin filament polymerization
GO_0032532Biological processregulation of microvillus length
GO_0051016Biological processbarbed-end actin filament capping
GO_0045773Biological processpositive regulation of axon extension
GO_0010976Biological processpositive regulation of neuron projection development
GO_0030042Biological processactin filament depolymerization
GO_0010592Biological processpositive regulation of lamellipodium assembly
GO_0030030Biological processcell projection organization
GO_0071363Biological processcellular response to growth factor stimulus
GO_0042989Biological processsequestering of actin monomers
GO_0032956Biological processregulation of actin cytoskeleton organization
GO_0010591Biological processregulation of lamellipodium assembly
GO_0032420Cellular componentstereocilium
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0030016Cellular componentmyofibril
GO_0070062Cellular componentextracellular exosome
GO_0005884Cellular componentactin filament
GO_0030175Cellular componentfilopodium
GO_0030426Cellular componentgrowth cone
GO_0005737Cellular componentcytoplasm
GO_0030027Cellular componentlamellipodium
GO_0005080Molecular functionprotein kinase C binding
GO_0003785Molecular functionactin monomer binding
GO_0045296Molecular functioncadherin binding
GO_0005546Molecular functionphosphatidylinositol-4,5-bisphosphate binding
GO_0051015Molecular functionactin filament binding
GO_0005524Molecular functionATP binding
GO_0003723Molecular functionRNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTWF2
Protein nameHCG2043378, isoform CRA_b (Twinfilin actin binding protein 2)
Twinfilin-2 (A6-related protein) (hA6RP) (Protein tyrosine kinase 9-like) (Twinfilin-1-like protein)
Twinfilin actin binding protein 2
SynonymsMSTP011
hCG_2043378
PTK9L
DescriptionFUNCTION: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity). .

AccessionsENST00000678330.1
ENST00000678549.1
A0A7I2V5D3
ENST00000676988.1
D6RG15
A0A7I2V5B1
Q6IBS0
ENST00000678838.1
ENST00000499914.2
ENST00000679296.1
A0A7I2YQM6
A0A7I2V3T5
A0A7I2V2U8
ENST00000676989.1
ENST00000305533.10