Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 10 studies | 30% ± 17% | |
ciliated cell | 7 studies | 34% ± 10% | |
basal cell | 5 studies | 30% ± 14% | |
endothelial cell | 4 studies | 21% ± 5% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 19% ± 2% | |
non-classical monocyte | 3 studies | 20% ± 5% | |
fibroblast | 3 studies | 22% ± 8% | |
glutamatergic neuron | 3 studies | 21% ± 3% | |
goblet cell | 3 studies | 19% ± 3% | |
CD8-positive, alpha-beta memory T cell | 3 studies | 17% ± 2% | |
gamma-delta T cell | 3 studies | 18% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3879.92 | 1445 / 1445 | 100% | 119.00 | 183 / 183 |
ovary | 100% | 1838.08 | 180 / 180 | 100% | 68.49 | 429 / 430 |
brain | 100% | 1992.72 | 2640 / 2642 | 100% | 57.37 | 702 / 705 |
breast | 100% | 2643.19 | 459 / 459 | 99% | 74.93 | 1112 / 1118 |
lung | 99% | 1985.93 | 573 / 578 | 100% | 72.49 | 1152 / 1155 |
prostate | 100% | 2617.17 | 245 / 245 | 99% | 54.44 | 496 / 502 |
kidney | 100% | 2251.42 | 89 / 89 | 99% | 49.27 | 889 / 901 |
uterus | 100% | 2357.56 | 170 / 170 | 98% | 61.02 | 451 / 459 |
bladder | 100% | 2965.95 | 21 / 21 | 98% | 65.32 | 494 / 504 |
adrenal gland | 100% | 2742.63 | 258 / 258 | 98% | 35.97 | 225 / 230 |
pancreas | 99% | 1590.41 | 326 / 328 | 98% | 50.54 | 175 / 178 |
stomach | 100% | 2128.59 | 359 / 359 | 98% | 82.49 | 279 / 286 |
intestine | 100% | 2980.37 | 966 / 966 | 97% | 70.71 | 513 / 527 |
thymus | 100% | 2856.31 | 653 / 653 | 97% | 63.45 | 586 / 605 |
skin | 100% | 3458.26 | 1805 / 1809 | 91% | 39.48 | 431 / 472 |
liver | 100% | 1818.96 | 226 / 226 | 90% | 27.03 | 364 / 406 |
blood vessel | 100% | 2464.19 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 1318.01 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 17.47 | 1 / 1 |
adipose | 100% | 2792.77 | 1203 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 60.86 | 44 / 45 |
eye | 0% | 0 | 0 / 0 | 85% | 26.62 | 68 / 80 |
heart | 83% | 719.26 | 712 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 59% | 13.53 | 17 / 29 |
peripheral blood | 54% | 558.58 | 504 / 929 | 0% | 0 | 0 / 0 |
muscle | 17% | 99.02 | 136 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030837 | Biological process | negative regulation of actin filament polymerization |
GO_0051016 | Biological process | barbed-end actin filament capping |
GO_0043538 | Biological process | regulation of actin phosphorylation |
GO_0010976 | Biological process | positive regulation of neuron projection development |
GO_0030042 | Biological process | actin filament depolymerization |
GO_0010613 | Biological process | positive regulation of cardiac muscle hypertrophy |
GO_0042989 | Biological process | sequestering of actin monomers |
GO_0010591 | Biological process | regulation of lamellipodium assembly |
GO_0032587 | Cellular component | ruffle membrane |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0030016 | Cellular component | myofibril |
GO_0005884 | Cellular component | actin filament |
GO_0005925 | Cellular component | focal adhesion |
GO_0005911 | Cellular component | cell-cell junction |
GO_0030175 | Cellular component | filopodium |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0003785 | Molecular function | actin monomer binding |
GO_0045296 | Molecular function | cadherin binding |
GO_0004713 | Molecular function | protein tyrosine kinase activity |
GO_0005546 | Molecular function | phosphatidylinositol-4,5-bisphosphate binding |
GO_0051015 | Molecular function | actin filament binding |
GO_0005524 | Molecular function | ATP binding |
GO_0005515 | Molecular function | protein binding |
GO_0003779 | Molecular function | actin binding |
Gene name | TWF1 |
Protein name | Twinfilin-1 Twinfilin-1 (Protein A6) (Protein tyrosine kinase 9) Twinfilin actin binding protein 1 |
Synonyms | PTK9 |
Description | FUNCTION: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity). . FUNCTION: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. . FUNCTION: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. . |
Accessions | ENST00000395510.7 [Q12792-2] Q12792 F8W645 ENST00000552521.5 [Q12792-4] ENST00000550371.1 ENST00000546506.5 F8VRG3 F8W1Q9 ENST00000548403.1 ENST00000546662.5 ENST00000547459.5 F8W1D0 F8VS81 ENST00000548315.5 [Q12792-3] |