Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 10 studies | 40% ± 12% | |
oligodendrocyte | 9 studies | 41% ± 10% | |
endothelial cell | 8 studies | 26% ± 6% | |
microglial cell | 7 studies | 39% ± 6% | |
ciliated cell | 6 studies | 35% ± 17% | |
natural killer cell | 6 studies | 19% ± 4% | |
CD8-positive, alpha-beta T cell | 6 studies | 19% ± 2% | |
classical monocyte | 5 studies | 18% ± 4% | |
plasmacytoid dendritic cell | 5 studies | 20% ± 3% | |
epithelial cell | 5 studies | 40% ± 24% | |
non-classical monocyte | 4 studies | 19% ± 4% | |
GABAergic neuron | 4 studies | 22% ± 3% | |
Mueller cell | 4 studies | 21% ± 3% | |
oligodendrocyte precursor cell | 4 studies | 18% ± 2% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 21% ± 3% | |
CD4-positive, alpha-beta T cell | 3 studies | 18% ± 0% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 18% ± 1% | |
myeloid cell | 3 studies | 19% ± 3% | |
lymphocyte | 3 studies | 24% ± 6% | |
glutamatergic neuron | 3 studies | 22% ± 3% | |
gamma-delta T cell | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
stomach | 100% | 3250.75 | 358 / 359 | 100% | 20.16 | 285 / 286 |
prostate | 100% | 4461.78 | 244 / 245 | 100% | 21.37 | 500 / 502 |
breast | 100% | 3638.15 | 459 / 459 | 99% | 17.53 | 1102 / 1118 |
intestine | 100% | 3458.74 | 963 / 966 | 99% | 19.80 | 521 / 527 |
kidney | 100% | 5121.60 | 89 / 89 | 98% | 16.24 | 884 / 901 |
brain | 98% | 3518.00 | 2596 / 2642 | 100% | 19.27 | 702 / 705 |
pancreas | 100% | 6998.44 | 328 / 328 | 98% | 13.05 | 174 / 178 |
thymus | 100% | 4647.45 | 652 / 653 | 97% | 11.56 | 589 / 605 |
lung | 100% | 6629.72 | 578 / 578 | 93% | 10.48 | 1070 / 1155 |
liver | 100% | 4035.24 | 226 / 226 | 90% | 9.49 | 366 / 406 |
skin | 99% | 2155.51 | 1786 / 1809 | 91% | 13.64 | 431 / 472 |
ovary | 100% | 4053.34 | 180 / 180 | 86% | 6.80 | 370 / 430 |
bladder | 100% | 2005.52 | 21 / 21 | 75% | 8.74 | 379 / 504 |
uterus | 99% | 2489.95 | 168 / 170 | 74% | 5.98 | 338 / 459 |
esophagus | 82% | 1332.93 | 1180 / 1445 | 89% | 13.16 | 163 / 183 |
adrenal gland | 100% | 4052.45 | 258 / 258 | 56% | 4.15 | 129 / 230 |
spleen | 100% | 15684.39 | 241 / 241 | 0% | 0 | 0 / 0 |
adipose | 99% | 2115.88 | 1186 / 1204 | 0% | 0 | 0 / 0 |
heart | 98% | 1597.83 | 840 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 95% | 1631.99 | 1266 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 94% | 3192.05 | 876 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 86% | 14.83 | 25 / 29 |
tonsil | 0% | 0 | 0 / 0 | 73% | 5.65 | 33 / 45 |
eye | 0% | 0 | 0 / 0 | 28% | 1.38 | 22 / 80 |
muscle | 15% | 142.69 | 123 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0046847 | Biological process | filopodium assembly |
GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
GO_0030334 | Biological process | regulation of cell migration |
GO_0016477 | Biological process | cell migration |
GO_0030032 | Biological process | lamellipodium assembly |
GO_0032587 | Cellular component | ruffle membrane |
GO_0030175 | Cellular component | filopodium |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0030027 | Cellular component | lamellipodium |
GO_0005737 | Cellular component | cytoplasm |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | SPATA13 |
Protein name | SPATA13 Spermatogenesis-associated protein 13 (APC-stimulated guanine nucleotide exchange factor 2) (Asef2) Spermatogenesis associated 13 |
Synonyms | |
Description | FUNCTION: Acts as a guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression. . |
Accessions | ENST00000424834.6 [Q96N96-6] ENST00000382108.8 [Q96N96-6] A0A024RDM6 ENST00000382095.8 [Q96N96-1] ENST00000409126.5 E9PFR9 ENST00000494772.5 Q5VX67 ENST00000488060.1 ENST00000434675.5 ENST00000454083.1 ENST00000399949.6 [Q96N96-2] V9GZ16 J3KQJ8 ENST00000343003.10 [Q96N96-3] Q96N96 |