Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 15 studies | 48% ± 23% | |
glutamatergic neuron | 11 studies | 81% ± 17% | |
GABAergic neuron | 10 studies | 70% ± 25% | |
endothelial cell | 6 studies | 42% ± 20% | |
interneuron | 6 studies | 62% ± 23% | |
retina horizontal cell | 6 studies | 70% ± 27% | |
cardiac muscle cell | 6 studies | 62% ± 23% | |
neuron | 5 studies | 49% ± 18% | |
microglial cell | 5 studies | 40% ± 21% | |
oligodendrocyte precursor cell | 4 studies | 29% ± 9% | |
retinal cone cell | 4 studies | 48% ± 18% | |
retinal ganglion cell | 4 studies | 87% ± 5% | |
GABAergic interneuron | 3 studies | 75% ± 11% | |
granule cell | 3 studies | 53% ± 32% | |
basal cell | 3 studies | 34% ± 24% | |
GABAergic amacrine cell | 3 studies | 61% ± 11% | |
OFF-bipolar cell | 3 studies | 55% ± 19% | |
ON-bipolar cell | 3 studies | 44% ± 29% | |
glycinergic amacrine cell | 3 studies | 73% ± 9% | |
amacrine cell | 3 studies | 74% ± 16% | |
retinal pigment epithelial cell | 3 studies | 37% ± 21% | |
fibroblast | 3 studies | 18% ± 1% | |
oligodendrocyte | 3 studies | 49% ± 24% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 80% | 1258.62 | 2109 / 2642 | 63% | 3.65 | 441 / 705 |
skin | 97% | 2132.09 | 1762 / 1809 | 12% | 0.98 | 55 / 472 |
prostate | 57% | 447.67 | 140 / 245 | 51% | 1.27 | 256 / 502 |
heart | 97% | 8382.05 | 839 / 861 | 0% | 0 | 0 / 0 |
esophagus | 34% | 323.36 | 493 / 1445 | 61% | 36.21 | 111 / 183 |
breast | 35% | 219.86 | 160 / 459 | 48% | 1.92 | 533 / 1118 |
kidney | 56% | 281.03 | 50 / 89 | 17% | 0.81 | 151 / 901 |
tonsil | 0% | 0 | 0 / 0 | 60% | 15.70 | 27 / 45 |
liver | 24% | 123.81 | 55 / 226 | 28% | 1.54 | 114 / 406 |
adrenal gland | 34% | 167.38 | 88 / 258 | 17% | 0.52 | 38 / 230 |
lung | 13% | 65.70 | 76 / 578 | 37% | 7.95 | 426 / 1155 |
uterus | 2% | 30.46 | 4 / 170 | 34% | 5.17 | 157 / 459 |
thymus | 11% | 53.74 | 73 / 653 | 21% | 2.50 | 126 / 605 |
pancreas | 1% | 1.84 | 2 / 328 | 28% | 1.44 | 49 / 178 |
bladder | 5% | 13.00 | 1 / 21 | 17% | 3.94 | 85 / 504 |
eye | 0% | 0 | 0 / 0 | 21% | 0.52 | 17 / 80 |
stomach | 5% | 20.01 | 19 / 359 | 14% | 0.77 | 40 / 286 |
intestine | 5% | 21.35 | 49 / 966 | 8% | 0.35 | 40 / 527 |
ovary | 2% | 5.99 | 3 / 180 | 5% | 0.15 | 21 / 430 |
adipose | 5% | 27.57 | 58 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 4% | 39.20 | 50 / 1335 | 0% | 0 | 0 / 0 |
muscle | 1% | 3.33 | 6 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 1% | 2.43 | 6 / 929 | 0% | 0 | 0 / 0 |
spleen | 0% | 2.13 | 1 / 241 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0098942 | Biological process | retrograde trans-synaptic signaling by trans-synaptic protein complex |
GO_0007165 | Biological process | signal transduction |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0051491 | Biological process | positive regulation of filopodium assembly |
GO_0048666 | Biological process | neuron development |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0007157 | Biological process | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules |
GO_0005886 | Cellular component | plasma membrane |
GO_0043197 | Cellular component | dendritic spine |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0043005 | Cellular component | neuron projection |
GO_0030425 | Cellular component | dendrite |
GO_0030175 | Cellular component | filopodium |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0045202 | Cellular component | synapse |
GO_0030426 | Cellular component | growth cone |
GO_0016605 | Cellular component | PML body |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0030054 | Cellular component | cell junction |
GO_0005634 | Cellular component | nucleus |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0050839 | Molecular function | cell adhesion molecule binding |
GO_0046982 | Molecular function | protein heterodimerization activity |
GO_0005509 | Molecular function | calcium ion binding |
Gene name | TENM2 |
Protein name | Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)] HCG38403, isoform CRA_b (Teneurin transmembrane protein 2) Teneurin transmembrane protein 2 |
Synonyms | TNM2 KIAA1127 ODZ2 hCG_38403 |
Description | FUNCTION: Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Promotes the formation of filopodia and enlarged growth cone in neuronal cells. Induces homophilic cell-cell adhesion (By similarity). May function as a cellular signal transducer. .; FUNCTION: [Isoform 2]: Acts as a ligand of the ADGRL1 receptor. Mediates axon guidance and heterophilic cell-cell adhesion. .; FUNCTION: [Ten-2 intracellular domain]: Induces gene transcription inhibition. . |
Accessions | A0A8Q3SIA3 ENST00000518659.6 [Q9NT68-1] F8VNQ3 ENST00000695885.1 ENST00000695961.1 A0A8Q3SIB5 A0A8Q3SI53 A0A8Q3SI97 ENST00000695962.1 ENST00000520394.5 Q9NT68 ENST00000695886.1 G3V106 ENST00000519204.5 |