Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 32 studies | 37% ± 19% | |
astrocyte | 17 studies | 42% ± 19% | |
pericyte | 14 studies | 35% ± 19% | |
oligodendrocyte precursor cell | 13 studies | 37% ± 17% | |
fibroblast | 12 studies | 37% ± 22% | |
epithelial cell | 8 studies | 40% ± 18% | |
ciliated cell | 8 studies | 30% ± 16% | |
retina horizontal cell | 6 studies | 37% ± 20% | |
mast cell | 6 studies | 20% ± 6% | |
Mueller cell | 6 studies | 48% ± 12% | |
basal cell | 6 studies | 29% ± 19% | |
type I pneumocyte | 6 studies | 29% ± 10% | |
oligodendrocyte | 5 studies | 25% ± 10% | |
capillary endothelial cell | 5 studies | 29% ± 14% | |
goblet cell | 5 studies | 34% ± 21% | |
club cell | 5 studies | 28% ± 11% | |
type II pneumocyte | 5 studies | 28% ± 7% | |
endothelial cell of artery | 4 studies | 26% ± 15% | |
retinal pigment epithelial cell | 4 studies | 39% ± 16% | |
enteroendocrine cell | 4 studies | 26% ± 9% | |
respiratory goblet cell | 4 studies | 32% ± 10% | |
smooth muscle cell | 4 studies | 24% ± 7% | |
ionocyte | 3 studies | 26% ± 6% | |
endothelial cell of sinusoid | 3 studies | 48% ± 21% | |
hepatic stellate cell | 3 studies | 38% ± 10% | |
microglial cell | 3 studies | 30% ± 14% | |
vein endothelial cell | 3 studies | 23% ± 5% | |
melanocyte | 3 studies | 62% ± 26% | |
glutamatergic neuron | 3 studies | 22% ± 5% | |
pancreatic ductal cell | 3 studies | 46% ± 18% | |
abnormal cell | 3 studies | 26% ± 6% | |
connective tissue cell | 3 studies | 42% ± 16% | |
intestinal crypt stem cell | 3 studies | 22% ± 4% | |
transit amplifying cell | 3 studies | 38% ± 30% | |
brush cell | 3 studies | 29% ± 8% | |
kidney loop of Henle epithelial cell | 3 studies | 35% ± 13% | |
renal principal cell | 3 studies | 44% ± 19% | |
mucus secreting cell | 3 studies | 30% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
stomach | 100% | 6500.49 | 359 / 359 | 98% | 37.11 | 280 / 286 |
skin | 100% | 6481.20 | 1808 / 1809 | 98% | 125.15 | 462 / 472 |
brain | 97% | 7268.89 | 2573 / 2642 | 99% | 66.00 | 701 / 705 |
pancreas | 100% | 4758.47 | 328 / 328 | 97% | 22.47 | 172 / 178 |
lung | 100% | 8061.45 | 578 / 578 | 95% | 30.63 | 1103 / 1155 |
thymus | 100% | 8157.44 | 653 / 653 | 94% | 23.13 | 567 / 605 |
ovary | 99% | 4558.35 | 179 / 180 | 92% | 23.05 | 395 / 430 |
intestine | 87% | 2935.19 | 840 / 966 | 99% | 33.14 | 522 / 527 |
prostate | 96% | 2582.60 | 234 / 245 | 88% | 14.61 | 443 / 502 |
breast | 100% | 3342.86 | 458 / 459 | 82% | 19.88 | 912 / 1118 |
kidney | 100% | 4618.31 | 89 / 89 | 80% | 17.77 | 721 / 901 |
esophagus | 81% | 1955.26 | 1164 / 1445 | 99% | 49.96 | 182 / 183 |
uterus | 87% | 1673.84 | 148 / 170 | 88% | 21.08 | 406 / 459 |
bladder | 86% | 1531.10 | 18 / 21 | 76% | 19.93 | 382 / 504 |
eye | 0% | 0 | 0 / 0 | 100% | 169.37 | 80 / 80 |
spleen | 100% | 3960.15 | 241 / 241 | 0% | 0 | 0 / 0 |
adipose | 100% | 3788.30 | 1203 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 20.40 | 42 / 45 |
blood vessel | 92% | 4019.83 | 1227 / 1335 | 0% | 0 | 0 / 0 |
adrenal gland | 51% | 758.76 | 131 / 258 | 23% | 4.18 | 54 / 230 |
muscle | 65% | 1398.57 | 522 / 803 | 0% | 0 | 0 / 0 |
liver | 48% | 703.66 | 108 / 226 | 17% | 4.59 | 68 / 406 |
heart | 31% | 407.11 | 268 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 2% | 29.74 | 20 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0051489 | Biological process | regulation of filopodium assembly |
GO_0007165 | Biological process | signal transduction |
GO_0008360 | Biological process | regulation of cell shape |
GO_0022409 | Biological process | positive regulation of cell-cell adhesion |
GO_0030705 | Biological process | cytoskeleton-dependent intracellular transport |
GO_0001726 | Cellular component | ruffle |
GO_0005730 | Cellular component | nucleolus |
GO_0005886 | Cellular component | plasma membrane |
GO_0032433 | Cellular component | filopodium tip |
GO_0043025 | Cellular component | neuronal cell body |
GO_0043005 | Cellular component | neuron projection |
GO_0031527 | Cellular component | filopodium membrane |
GO_0030175 | Cellular component | filopodium |
GO_0005829 | Cellular component | cytosol |
GO_0005938 | Cellular component | cell cortex |
GO_0030027 | Cellular component | lamellipodium |
GO_0016459 | Cellular component | myosin complex |
GO_0005547 | Molecular function | phosphatidylinositol-3,4,5-trisphosphate binding |
GO_0030507 | Molecular function | spectrin binding |
GO_0051015 | Molecular function | actin filament binding |
GO_0000146 | Molecular function | microfilament motor activity |
GO_0005524 | Molecular function | ATP binding |
GO_0060002 | Molecular function | plus-end directed microfilament motor activity |
GO_0005516 | Molecular function | calmodulin binding |
GO_0005515 | Molecular function | protein binding |
Gene name | MYO10 |
Protein name | Myosin X MYO10 protein Unconventional myosin-X (Unconventional myosin-10) |
Synonyms | KIAA0799 |
Description | FUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as a plus end-directed motor. Moves with higher velocity and takes larger steps on actin bundles than on single actin filaments . The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. In hippocampal neurons it induces the formation of dendritic filopodia by trafficking the actin-remodeling protein VASP to the tips of filopodia, where it promotes actin elongation. Plays a role in formation of the podosome belt in osteoclasts. .; FUNCTION: [Isoform Headless]: Functions as a dominant-negative regulator of isoform 1, suppressing its filopodia-inducing and axon outgrowth-promoting activities. In hippocampal neurons, it increases VASP retention in spine heads to induce spine formation and spine head expansion (By similarity). . |
Accessions | ENST00000274203.13 Q9HD67 A0A0A0MQX1 E9PCN3 ENST00000502436.5 ENST00000515803.5 Q6IPD7 ENST00000505695.5 ENST00000513882.5 D6RGD1 E9PEW5 ENST00000507288.1 [Q9HD67-2] ENST00000513610.6 [Q9HD67-1] |