LCP1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
macrophage	47 studies	51% ± 19%	Explore
natural killer cell	45 studies	63% ± 19%	Explore
B cell	44 studies	41% ± 15%	Explore
CD8-positive, alpha-beta T cell	40 studies	55% ± 16%	Explore
T cell	37 studies	50% ± 20%	Explore
CD4-positive, alpha-beta T cell	33 studies	52% ± 17%	Explore
conventional dendritic cell	32 studies	71% ± 18%	Explore
dendritic cell	31 studies	63% ± 23%	Explore
classical monocyte	29 studies	74% ± 16%	Explore
regulatory T cell	28 studies	51% ± 17%	Explore
monocyte	27 studies	61% ± 21%	Explore
non-classical monocyte	25 studies	83% ± 12%	Explore
mast cell	24 studies	39% ± 20%	Explore
mature NK T cell	23 studies	58% ± 18%	Explore
plasmacytoid dendritic cell	23 studies	62% ± 15%	Explore
memory B cell	20 studies	50% ± 13%	Explore
naive B cell	20 studies	40% ± 13%	Explore
gamma-delta T cell	19 studies	66% ± 15%	Explore
myeloid cell	19 studies	55% ± 26%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	39% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	17 studies	64% ± 16%	Explore
mucosal invariant T cell	17 studies	64% ± 19%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	71% ± 16%	Explore
neutrophil	16 studies	60% ± 19%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	51% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	13 studies	59% ± 18%	Explore
CD4-positive, alpha-beta memory T cell	13 studies	59% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	69% ± 12%	Explore
leukocyte	10 studies	48% ± 19%	Explore
plasma cell	9 studies	36% ± 21%	Explore
innate lymphoid cell	9 studies	49% ± 13%	Explore
plasmablast	9 studies	49% ± 17%	Explore
microglial cell	9 studies	28% ± 10%	Explore
alveolar macrophage	8 studies	57% ± 18%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	70% ± 20%	Explore
mononuclear phagocyte	7 studies	53% ± 19%	Explore
hematopoietic stem cell	7 studies	45% ± 18%	Explore
T follicular helper cell	7 studies	45% ± 12%	Explore
CD4-positive helper T cell	6 studies	45% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	60% ± 16%	Explore
hematopoietic precursor cell	6 studies	64% ± 20%	Explore
platelet	6 studies	43% ± 23%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	67% ± 21%	Explore
erythrocyte	6 studies	35% ± 9%	Explore
precursor B cell	6 studies	47% ± 20%	Explore
intermediate monocyte	6 studies	67% ± 25%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	60% ± 14%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	62% ± 15%	Explore
exhausted T cell	5 studies	69% ± 9%	Explore
lymphocyte	5 studies	55% ± 21%	Explore
T-helper 17 cell	5 studies	63% ± 20%	Explore
group 3 innate lymphoid cell	5 studies	73% ± 14%	Explore
immature B cell	5 studies	55% ± 12%	Explore
inflammatory macrophage	5 studies	44% ± 21%	Explore
double negative thymocyte	5 studies	67% ± 10%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	52% ± 23%	Explore
monocyte-derived dendritic cell	4 studies	54% ± 32%	Explore
pro-B cell	4 studies	37% ± 19%	Explore
germinal center B cell	4 studies	62% ± 22%	Explore
luminal cell of prostate epithelium	4 studies	22% ± 2%	Explore
granulocyte	4 studies	62% ± 22%	Explore
T-helper 1 cell	4 studies	65% ± 12%	Explore
Langerhans cell	3 studies	70% ± 5%	Explore
common myeloid progenitor	3 studies	46% ± 15%	Explore
tissue-resident macrophage	3 studies	53% ± 17%	Explore
intraepithelial lymphocyte	3 studies	55% ± 21%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	61% ± 9%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	20 studies	61% ± 10%	Explore
lung	10 studies	35% ± 14%	Explore
liver	6 studies	29% ± 15%	Explore
bone marrow	5 studies	45% ± 20%	Explore
lymph node	4 studies	43% ± 7%	Explore
intestine	3 studies	24% ± 4%	Explore
brain	3 studies	24% ± 2%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	96%	9379.70	234 / 245	100%	295.53	501 / 502
lung	100%	15153.43	578 / 578	92%	114.43	1064 / 1155
breast	93%	3570.67	427 / 459	94%	115.03	1056 / 1118
bladder	71%	2528.81	15 / 21	78%	83.16	394 / 504
skin	63%	1712.49	1148 / 1809	76%	97.36	359 / 472
liver	77%	2796.93	174 / 226	57%	39.35	232 / 406
adrenal gland	93%	3458.67	241 / 258	40%	24.64	92 / 230
intestine	66%	3552.50	642 / 966	65%	50.43	345 / 527
stomach	56%	1488.28	202 / 359	72%	64.75	205 / 286
uterus	41%	961.42	70 / 170	73%	59.58	334 / 459
thymus	40%	1270.76	262 / 653	73%	101.27	440 / 605
esophagus	41%	1009.14	588 / 1445	71%	51.37	130 / 183
kidney	34%	1137.72	30 / 89	75%	70.16	674 / 901
lymph node	0%	0	0 / 0	100%	1044.45	29 / 29
peripheral blood	100%	177732.47	929 / 929	0%	0	0 / 0
spleen	100%	39299.51	241 / 241	0%	0	0 / 0
adipose	99%	6946.98	1188 / 1204	0%	0	0 / 0
pancreas	13%	311.09	43 / 328	85%	81.90	152 / 178
tonsil	0%	0	0 / 0	93%	134.17	42 / 45
ovary	18%	413.62	32 / 180	71%	43.67	305 / 430
brain	19%	470.08	501 / 2642	49%	25.53	342 / 705
blood vessel	60%	2504.18	802 / 1335	0%	0	0 / 0
heart	25%	636.53	216 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	11%	6.93	9 / 80
muscle	1%	18.76	8 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1