Interactors | Protein name | Directionality | Classification | |
|---|---|---|---|---|
| 1 | EDN1-EDNRA | EDN1_HUMAN - EDNRA_HUMAN | Ligand-Receptor | Signaling by Endothelin |
| Name | protein kinase A signaling |
| ID | GO_0010737 |
| collection_id | Biological process |
| Exact synonym | protein kinase A signal transduction |
| Description | An intracellular signaling cassette that starts with the activation of protein kinase A (PKA), and ends with the regulation of a downstream cellular process, e.g. transcription. The PKA catalytic subunit (PKA-C) is normally present in a complex with its regulatory subunit, PKA-R. The inhibitory action of PKA-R is released upon cAMP binding, which results in the activation of PKA-C. |
| Related synonym | PKA signaling cascade, protein kinase A signaling cascade, protein kinase A signalling cascade |
| External URL | |
| Genes |