GAL report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GAL at tissue level.

III. Associated gene sets

GO_0007218Biological processneuropeptide signaling pathway
GO_0043627Biological processresponse to estrogen
GO_0007631Biological processfeeding behavior
GO_0035902Biological processresponse to immobilization stress
GO_0051795Biological processpositive regulation of timing of catagen
GO_0032868Biological processresponse to insulin
GO_0019933Biological processcAMP-mediated signaling
GO_0010737Biological processprotein kinase A signaling
GO_0050672Biological processnegative regulation of lymphocyte proliferation
GO_0031943Biological processregulation of glucocorticoid metabolic process
GO_1902608Biological processpositive regulation of large conductance calcium-activated potassium channel activity
GO_0030073Biological processinsulin secretion
GO_0009410Biological processresponse to xenobiotic stimulus
GO_0043065Biological processpositive regulation of apoptotic process
GO_0051464Biological processpositive regulation of cortisol secretion
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0043025Cellular componentneuronal cell body
GO_0030141Cellular componentsecretory granule
GO_0031763Molecular functiongalanin receptor binding
GO_0031766Molecular functiontype 3 galanin receptor binding
GO_0031764Molecular functiontype 1 galanin receptor binding
GO_0004966Molecular functiongalanin receptor activity
GO_0031765Molecular functiontype 2 galanin receptor binding
GO_0005515Molecular functionprotein binding
GO_0005184Molecular functionneuropeptide hormone activity

IV. Literature review

[source]
Gene nameGAL
Protein nameGalanin peptides [Cleaved into: Galanin; Galanin message-associated peptide (GMAP)]
SynonymsGALN
GAL1
GLNN
DescriptionFUNCTION: Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion. .

AccessionsENST00000265643.4
P22466