Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 23 studies | 33% ± 15% | |
| astrocyte | 19 studies | 51% ± 20% | |
| fibroblast | 16 studies | 30% ± 10% | |
| oligodendrocyte | 16 studies | 40% ± 18% | |
| oligodendrocyte precursor cell | 14 studies | 41% ± 19% | |
| macrophage | 13 studies | 32% ± 17% | |
| microglial cell | 13 studies | 36% ± 14% | |
| glutamatergic neuron | 12 studies | 57% ± 26% | |
| GABAergic neuron | 11 studies | 50% ± 24% | |
| pericyte | 11 studies | 33% ± 15% | |
| neuron | 10 studies | 50% ± 19% | |
| dendritic cell | 10 studies | 36% ± 15% | |
| smooth muscle cell | 9 studies | 32% ± 11% | |
| endothelial cell of lymphatic vessel | 8 studies | 34% ± 12% | |
| amacrine cell | 8 studies | 35% ± 12% | |
| retinal rod cell | 8 studies | 41% ± 14% | |
| epithelial cell | 8 studies | 30% ± 16% | |
| adipocyte | 8 studies | 29% ± 9% | |
| ciliated cell | 8 studies | 27% ± 10% | |
| type II pneumocyte | 7 studies | 44% ± 16% | |
| retinal ganglion cell | 7 studies | 69% ± 22% | |
| retinal cone cell | 7 studies | 65% ± 11% | |
| interneuron | 6 studies | 60% ± 23% | |
| myeloid cell | 6 studies | 28% ± 7% | |
| retina horizontal cell | 6 studies | 49% ± 11% | |
| Mueller cell | 6 studies | 30% ± 13% | |
| basal cell | 6 studies | 36% ± 18% | |
| retinal bipolar neuron | 5 studies | 39% ± 7% | |
| club cell | 5 studies | 29% ± 9% | |
| type I pneumocyte | 5 studies | 32% ± 7% | |
| granule cell | 4 studies | 40% ± 11% | |
| retinal pigment epithelial cell | 4 studies | 53% ± 23% | |
| OFF-bipolar cell | 4 studies | 53% ± 18% | |
| ON-bipolar cell | 4 studies | 58% ± 19% | |
| pancreatic A cell | 3 studies | 47% ± 20% | |
| type B pancreatic cell | 3 studies | 48% ± 25% | |
| conventional dendritic cell | 3 studies | 31% ± 14% | |
| GABAergic interneuron | 3 studies | 51% ± 4% | |
| glial cell | 3 studies | 30% ± 11% | |
| progenitor cell | 3 studies | 35% ± 8% | |
| B cell | 3 studies | 21% ± 4% | |
| mononuclear phagocyte | 3 studies | 23% ± 7% | |
| vein endothelial cell | 3 studies | 29% ± 16% | |
| lymphocyte | 3 studies | 19% ± 3% | |
| GABAergic amacrine cell | 3 studies | 41% ± 8% | |
| glycinergic amacrine cell | 3 studies | 34% ± 1% | |
| rod bipolar cell | 3 studies | 50% ± 9% | |
| endothelial cell of vascular tree | 3 studies | 31% ± 17% | |
| hepatocyte | 3 studies | 48% ± 31% | |
| abnormal cell | 3 studies | 30% ± 10% | |
| connective tissue cell | 3 studies | 19% ± 2% | |
| ependymal cell | 3 studies | 61% ± 17% | |
| adventitial cell | 3 studies | 21% ± 6% | |
| myofibroblast cell | 3 studies | 33% ± 15% | |
| alveolar macrophage | 3 studies | 33% ± 8% | |
| monocyte | 3 studies | 33% ± 3% | |
| goblet cell | 3 studies | 39% ± 28% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 9342.41 | 2642 / 2642 | 100% | 81.15 | 705 / 705 |
| thymus | 100% | 7618.64 | 653 / 653 | 100% | 28.65 | 604 / 605 |
| kidney | 100% | 3702.22 | 89 / 89 | 100% | 19.97 | 899 / 901 |
| breast | 100% | 3790.15 | 459 / 459 | 100% | 16.97 | 1114 / 1118 |
| esophagus | 100% | 3420.27 | 1445 / 1445 | 99% | 12.11 | 182 / 183 |
| prostate | 100% | 4070.03 | 245 / 245 | 99% | 12.41 | 498 / 502 |
| adrenal gland | 100% | 5211.70 | 258 / 258 | 99% | 50.61 | 227 / 230 |
| uterus | 100% | 5560.88 | 170 / 170 | 98% | 12.68 | 452 / 459 |
| lung | 99% | 3830.25 | 575 / 578 | 99% | 13.72 | 1138 / 1155 |
| bladder | 100% | 3932.38 | 21 / 21 | 97% | 10.56 | 487 / 504 |
| skin | 100% | 4368.34 | 1807 / 1809 | 94% | 14.33 | 445 / 472 |
| pancreas | 95% | 2032.87 | 310 / 328 | 98% | 13.48 | 175 / 178 |
| intestine | 100% | 3214.56 | 964 / 966 | 92% | 8.16 | 484 / 527 |
| stomach | 99% | 2449.04 | 355 / 359 | 91% | 8.13 | 261 / 286 |
| ovary | 100% | 6801.49 | 180 / 180 | 81% | 6.88 | 349 / 430 |
| liver | 98% | 2257.48 | 221 / 226 | 77% | 6.26 | 314 / 406 |
| adipose | 100% | 3618.90 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3077.11 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 11.08 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 6.30 | 1 / 1 |
| blood vessel | 100% | 3256.52 | 1329 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 97% | 2191.95 | 779 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 15.86 | 28 / 29 |
| heart | 92% | 1831.85 | 792 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 64% | 6.75 | 51 / 80 |
| peripheral blood | 21% | 383.61 | 193 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_2000114 | Biological process | regulation of establishment of cell polarity |
| GO_0045773 | Biological process | positive regulation of axon extension |
| GO_0050771 | Biological process | negative regulation of axonogenesis |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_0030154 | Biological process | cell differentiation |
| GO_0007015 | Biological process | actin filament organization |
| GO_0090316 | Biological process | positive regulation of intracellular protein transport |
| GO_0007399 | Biological process | nervous system development |
| GO_0050770 | Biological process | regulation of axonogenesis |
| GO_0012505 | Cellular component | endomembrane system |
| GO_0016020 | Cellular component | membrane |
| GO_0043204 | Cellular component | perikaryon |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0030425 | Cellular component | dendrite |
| GO_0030175 | Cellular component | filopodium |
| GO_0005829 | Cellular component | cytosol |
| GO_0070161 | Cellular component | anchoring junction |
| GO_0030426 | Cellular component | growth cone |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0030424 | Cellular component | axon |
| GO_0030027 | Cellular component | lamellipodium |
| GO_0005515 | Molecular function | protein binding |
| Gene name | RUFY3 |
| Protein name | Protein RUFY3 (RUN and FYVE domain-containing protein 3) (Rap2-interacting protein x) (RIPx) (Single axon-regulated protein) (Singar) RUN and FYVE domain containing 3 |
| Synonyms | KIAA0871 |
| Description | FUNCTION: Plays a role in the generation of neuronal polarity formation and axon growth (By similarity). Implicated in the formation of a single axon by developing neurons (By similarity). May inhibit the formation of additional axons by inhibition of PI3K in minor neuronal processes (By similarity). Plays a role in the formation of F-actin-enriched protrusive structures at the cell periphery . Plays a role in cytoskeletal organization by regulating the subcellular localization of FSCN1 and DBN1 at axonal growth cones (By similarity). Promotes gastric cancer cell migration and invasion in a PAK1-dependent manner . . |
| Accessions | Q7L099 ENST00000502653.5 [Q7L099-4] ENST00000381006.8 [Q7L099-3] ENST00000513597.5 ENST00000503876.5 ENST00000514898.1 H0Y8I0 D6RCQ1 D6REM9 ENST00000417478.6 [Q7L099-2] H0Y8G6 D6RH24 ENST00000226328.8 [Q7L099-1] ENST00000512103.5 ENST00000504805.6 |