ARHGAP22 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte	15 studies	36% ± 14%	Explore
microglial cell	15 studies	53% ± 23%	Explore
oligodendrocyte precursor cell	11 studies	42% ± 20%	Explore
macrophage	10 studies	33% ± 15%	Explore
dendritic cell	6 studies	20% ± 2%	Explore
myeloid cell	6 studies	31% ± 16%	Explore
GABAergic neuron	5 studies	36% ± 19%	Explore
fibroblast	3 studies	23% ± 6%	Explore
glutamatergic neuron	3 studies	62% ± 9%	Explore
astrocyte	3 studies	27% ± 14%	Explore

Name	Number of supported studies	Average coverage
brain	10 studies	34% ± 16%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	1290.87	2639 / 2642	100%	10.91	703 / 705
thymus	99%	853.42	649 / 653	100%	7.24	603 / 605
ovary	97%	561.52	174 / 180	85%	2.05	365 / 430
lung	84%	263.97	485 / 578	80%	2.38	928 / 1155
skin	88%	1043.19	1593 / 1809	76%	3.40	359 / 472
breast	75%	204.20	342 / 459	88%	2.89	982 / 1118
adrenal gland	84%	229.40	216 / 258	74%	7.82	171 / 230
prostate	96%	411.24	236 / 245	61%	1.19	306 / 502
uterus	64%	160.02	109 / 170	84%	3.49	385 / 459
bladder	76%	276.57	16 / 21	64%	2.15	322 / 504
pancreas	49%	102.75	160 / 328	91%	3.11	162 / 178
kidney	49%	127.19	44 / 89	88%	3.48	790 / 901
esophagus	78%	223.79	1127 / 1445	58%	1.27	107 / 183
intestine	80%	223.89	775 / 966	52%	1.42	273 / 527
ureter	0%	0	0 / 0	100%	5.06	1 / 1
blood vessel	98%	751.97	1310 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	3.81	42 / 45
stomach	38%	92.06	135 / 359	52%	1.08	150 / 286
heart	89%	333.42	762 / 861	0%	0	0 / 0
adipose	88%	308.69	1063 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	86%	2.40	25 / 29
eye	0%	0	0 / 0	78%	2.81	62 / 80
spleen	58%	161.46	140 / 241	0%	0	0 / 0
muscle	50%	106.14	400 / 803	0%	0	0 / 0
liver	15%	31.09	33 / 226	28%	0.86	114 / 406
peripheral blood	20%	41.22	190 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007165	Biological process	signal transduction
GO_0051056	Biological process	regulation of small GTPase mediated signal transduction
GO_0001525	Biological process	angiogenesis
GO_0030154	Biological process	cell differentiation
GO_0099175	Biological process	regulation of postsynapse organization
GO_0090630	Biological process	activation of GTPase activity
GO_0098978	Cellular component	glutamatergic synapse
GO_0005829	Cellular component	cytosol
GO_0005925	Cellular component	focal adhesion
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0005096	Molecular function	GTPase activator activity

Gene name	ARHGAP22
Protein name	Rho GTPase activating protein 22 Rho GTPase-activating protein 22 (Rho-type GTPase-activating protein 22) ARHGAP22
Synonyms	RHOGAP2 hCG_2042896
Description	FUNCTION: Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity). .
Accessions	D6RBJ8 ENST00000374170.5 Q7Z5H3 ENST00000249601.9 [Q7Z5H3-1] ENST00000477708.6 ENST00000417912.6 [Q7Z5H3-2] A6NJ38 ENST00000435790.6 [Q7Z5H3-5] D6R9V6 ENST00000460425.1 A6NHM7 ENST00000417247.6 [Q7Z5H3-3] A0A2X0SFC0 ENST00000374172.5

ARHGAP22 report