PRSS12 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PRSS12 at tissue level.

III. Associated gene sets

GO_0006887Biological processexocytosis
GO_0031638Biological processzymogen activation
GO_0043083Cellular componentsynaptic cleft
GO_0043195Cellular componentterminal bouton
GO_0098978Cellular componentglutamatergic synapse
GO_0030424Cellular componentaxon
GO_0098793Cellular componentpresynapse
GO_0005886Cellular componentplasma membrane
GO_0031410Cellular componentcytoplasmic vesicle
GO_0030425Cellular componentdendrite
GO_0008236Molecular functionserine-type peptidase activity
GO_0004252Molecular functionserine-type endopeptidase activity

IV. Literature review

[source]
Gene namePRSS12
Protein nameNeurotrypsin (EC 3.4.21.-) (Leydin) (Motopsin) (Serine protease 12)
Synonyms
DescriptionFUNCTION: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. .

AccessionsP56730
ENST00000296498.3