Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| CD4-positive, alpha-beta T cell | 7 studies | 20% ± 3% | |
| mucosal invariant T cell | 5 studies | 21% ± 1% | |
| naive thymus-derived CD4-positive, alpha-beta T cell | 5 studies | 21% ± 8% | |
| plasma cell | 3 studies | 21% ± 4% | |
| gamma-delta T cell | 3 studies | 20% ± 4% |
Insufficient scRNA-seq data for expression of KCNA3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 274.93 | 578 / 578 | 74% | 4.23 | 850 / 1155 |
| brain | 80% | 64.62 | 2108 / 2642 | 51% | 1.50 | 359 / 705 |
| thymus | 92% | 72.95 | 602 / 653 | 38% | 2.05 | 229 / 605 |
| stomach | 69% | 38.02 | 247 / 359 | 52% | 2.52 | 148 / 286 |
| breast | 53% | 24.60 | 241 / 459 | 49% | 1.61 | 549 / 1118 |
| spleen | 100% | 316.81 | 241 / 241 | 0% | 0 | 0 / 0 |
| intestine | 67% | 93.66 | 643 / 966 | 33% | 1.12 | 176 / 527 |
| peripheral blood | 98% | 362.71 | 915 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 9.50 | 27 / 29 |
| ovary | 67% | 24.57 | 121 / 180 | 20% | 0.43 | 87 / 430 |
| kidney | 39% | 29.61 | 35 / 89 | 46% | 1.22 | 416 / 901 |
| uterus | 58% | 20.25 | 99 / 170 | 21% | 0.44 | 98 / 459 |
| esophagus | 32% | 10.64 | 460 / 1445 | 45% | 1.66 | 83 / 183 |
| adipose | 75% | 39.15 | 906 / 1204 | 0% | 0 | 0 / 0 |
| prostate | 53% | 23.65 | 130 / 245 | 19% | 0.38 | 93 / 502 |
| bladder | 48% | 29.62 | 10 / 21 | 22% | 0.70 | 112 / 504 |
| tonsil | 0% | 0 | 0 / 0 | 64% | 2.93 | 29 / 45 |
| skin | 20% | 6.68 | 357 / 1809 | 44% | 1.75 | 207 / 472 |
| pancreas | 21% | 5.67 | 68 / 328 | 41% | 1.12 | 73 / 178 |
| adrenal gland | 22% | 7.43 | 56 / 258 | 38% | 1.98 | 87 / 230 |
| liver | 41% | 13.20 | 92 / 226 | 7% | 0.16 | 30 / 406 |
| heart | 31% | 12.58 | 271 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 29% | 14.46 | 385 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 5% | 0.12 | 4 / 80 |
| muscle | 1% | 0.24 | 7 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0051260 | Biological process | protein homooligomerization |
| GO_0006813 | Biological process | potassium ion transport |
| GO_0071805 | Biological process | potassium ion transmembrane transport |
| GO_0021554 | Biological process | optic nerve development |
| GO_0022038 | Biological process | corpus callosum development |
| GO_0001508 | Biological process | action potential |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0045121 | Cellular component | membrane raft |
| GO_0016020 | Cellular component | membrane |
| GO_0042734 | Cellular component | presynaptic membrane |
| GO_0044305 | Cellular component | calyx of Held |
| GO_0045211 | Cellular component | postsynaptic membrane |
| GO_0030424 | Cellular component | axon |
| GO_0008076 | Cellular component | voltage-gated potassium channel complex |
| GO_0015271 | Molecular function | outward rectifier potassium channel activity |
| GO_0005251 | Molecular function | delayed rectifier potassium channel activity |
| GO_0005244 | Molecular function | voltage-gated monoatomic ion channel activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | KCNA3 |
| Protein name | Potassium voltage-gated channel subfamily A member 3 Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3) |
| Synonyms | HGK5 |
| Description | FUNCTION: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. |
| Accessions | P22001 ENST00000697411.1 ENST00000685980.2 ENST00000369769.4 ENST00000697412.1 ENST00000697409.1 A0A8V8TMD4 ENST00000697410.1 |