Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte precursor cell | 13 studies | 36% ± 18% | |
| GABAergic neuron | 8 studies | 40% ± 16% | |
| glutamatergic neuron | 6 studies | 29% ± 10% | |
| interneuron | 6 studies | 36% ± 12% | |
| astrocyte | 5 studies | 27% ± 9% | |
| GABAergic interneuron | 3 studies | 49% ± 24% | |
| neuron | 3 studies | 38% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 31% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 1758.90 | 2607 / 2642 | 98% | 53.72 | 689 / 705 |
| breast | 55% | 527.92 | 254 / 459 | 50% | 9.01 | 557 / 1118 |
| intestine | 88% | 2138.74 | 850 / 966 | 2% | 0.14 | 9 / 527 |
| prostate | 77% | 711.10 | 189 / 245 | 1% | 0.05 | 7 / 502 |
| bladder | 71% | 393.52 | 15 / 21 | 2% | 0.15 | 12 / 504 |
| esophagus | 71% | 1246.61 | 1021 / 1445 | 2% | 0.20 | 4 / 183 |
| adrenal gland | 22% | 142.19 | 56 / 258 | 37% | 8.62 | 86 / 230 |
| ovary | 14% | 70.23 | 25 / 180 | 38% | 6.35 | 164 / 430 |
| kidney | 1% | 3.43 | 1 / 89 | 45% | 6.31 | 408 / 901 |
| stomach | 44% | 529.99 | 158 / 359 | 2% | 0.17 | 6 / 286 |
| skin | 6% | 22.79 | 107 / 1809 | 27% | 9.85 | 129 / 472 |
| heart | 30% | 150.57 | 262 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 24% | 4.11 | 19 / 80 |
| uterus | 12% | 65.40 | 20 / 170 | 3% | 0.20 | 13 / 459 |
| adipose | 13% | 79.81 | 154 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 12% | 107.28 | 161 / 1335 | 0% | 0 | 0 / 0 |
| thymus | 4% | 15.71 | 26 / 653 | 5% | 0.58 | 33 / 605 |
| pancreas | 2% | 8.05 | 6 / 328 | 7% | 0.32 | 12 / 178 |
| lung | 2% | 6.10 | 10 / 578 | 3% | 0.33 | 38 / 1155 |
| liver | 1% | 2.57 | 2 / 226 | 0% | 0.04 | 1 / 406 |
| spleen | 0% | 1.22 | 1 / 241 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.90 | 2 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0042391 | Biological process | regulation of membrane potential |
| GO_0050804 | Biological process | modulation of chemical synaptic transmission |
| GO_0035235 | Biological process | ionotropic glutamate receptor signaling pathway |
| GO_0034220 | Biological process | monoatomic ion transmembrane transport |
| GO_0007196 | Biological process | adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway |
| GO_0007216 | Biological process | G protein-coupled glutamate receptor signaling pathway |
| GO_0099505 | Biological process | regulation of presynaptic membrane potential |
| GO_0060078 | Biological process | regulation of postsynaptic membrane potential |
| GO_0007215 | Biological process | glutamate receptor signaling pathway |
| GO_0035249 | Biological process | synaptic transmission, glutamatergic |
| GO_0051967 | Biological process | negative regulation of synaptic transmission, glutamatergic |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0098839 | Cellular component | postsynaptic density membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0043204 | Cellular component | perikaryon |
| GO_0043195 | Cellular component | terminal bouton |
| GO_0042734 | Cellular component | presynaptic membrane |
| GO_0030425 | Cellular component | dendrite |
| GO_0030424 | Cellular component | axon |
| GO_0032839 | Cellular component | dendrite cytoplasm |
| GO_0032983 | Cellular component | kainate selective glutamate receptor complex |
| GO_0008066 | Molecular function | glutamate receptor activity |
| GO_1904315 | Molecular function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential |
| GO_0004970 | Molecular function | glutamate-gated receptor activity |
| GO_0015277 | Molecular function | kainate selective glutamate receptor activity |
| GO_0001640 | Molecular function | adenylate cyclase inhibiting G protein-coupled glutamate receptor activity |
| GO_0099507 | Molecular function | ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential |
| Gene name | GRIK3 |
| Protein name | Glutamate receptor Glutamate receptor 7 Glutamate receptor ionotropic, kainate 3 (GluK3) (Excitatory amino acid receptor 5) (EAA5) (Glutamate receptor 7) (GluR-7) (GluR7) |
| Synonyms | GLUR7 |
| Description | FUNCTION: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA. FUNCTION: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. . |
| Accessions | Q96SC1 Q96SC2 Q96QG5 ENST00000373093.4 [Q13003-2] Q96SC0 Q13003 ENST00000373091.8 [Q13003-1] |
