Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3117.94 | 1445 / 1445 | 100% | 130.26 | 183 / 183 |
| ovary | 100% | 2065.01 | 180 / 180 | 100% | 124.94 | 430 / 430 |
| uterus | 100% | 2648.43 | 170 / 170 | 100% | 115.77 | 459 / 459 |
| skin | 100% | 2996.53 | 1808 / 1809 | 100% | 133.41 | 472 / 472 |
| intestine | 100% | 2893.60 | 966 / 966 | 100% | 117.43 | 526 / 527 |
| thymus | 100% | 1787.93 | 651 / 653 | 100% | 104.35 | 605 / 605 |
| stomach | 100% | 1925.25 | 359 / 359 | 100% | 126.89 | 285 / 286 |
| lung | 100% | 5026.28 | 578 / 578 | 99% | 109.55 | 1148 / 1155 |
| breast | 100% | 2678.36 | 459 / 459 | 99% | 103.02 | 1107 / 1118 |
| prostate | 100% | 2196.49 | 244 / 245 | 99% | 73.91 | 499 / 502 |
| bladder | 100% | 2773.19 | 21 / 21 | 99% | 112.61 | 498 / 504 |
| adrenal gland | 100% | 2140.96 | 257 / 258 | 99% | 71.51 | 228 / 230 |
| kidney | 99% | 1846.52 | 88 / 89 | 99% | 92.05 | 895 / 901 |
| liver | 92% | 1179.65 | 209 / 226 | 100% | 67.64 | 405 / 406 |
| brain | 86% | 1605.20 | 2272 / 2642 | 100% | 114.45 | 705 / 705 |
| pancreas | 84% | 920.51 | 274 / 328 | 99% | 120.03 | 177 / 178 |
| adipose | 100% | 3302.42 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 126.38 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 404.88 | 29 / 29 |
| peripheral blood | 100% | 38682.32 | 929 / 929 | 0% | 0 | 0 / 0 |
| spleen | 100% | 9440.67 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 135.25 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 122.24 | 1 / 1 |
| blood vessel | 100% | 2874.67 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 1434.74 | 846 / 861 | 0% | 0 | 0 / 0 |
| muscle | 97% | 1742.58 | 778 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0032956 | Biological process | regulation of actin cytoskeleton organization |
| GO_0150052 | Biological process | regulation of postsynapse assembly |
| GO_0090630 | Biological process | activation of GTPase activity |
| GO_0007163 | Biological process | establishment or maintenance of cell polarity |
| GO_0030865 | Biological process | cortical cytoskeleton organization |
| GO_0030036 | Biological process | actin cytoskeleton organization |
| GO_1903078 | Biological process | positive regulation of protein localization to plasma membrane |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0016601 | Biological process | Rac protein signal transduction |
| GO_0007015 | Biological process | actin filament organization |
| GO_0007266 | Biological process | Rho protein signal transduction |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0008360 | Biological process | regulation of cell shape |
| GO_0060326 | Biological process | cell chemotaxis |
| GO_1900027 | Biological process | regulation of ruffle assembly |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0030667 | Cellular component | secretory granule membrane |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0031410 | Cellular component | cytoplasmic vesicle |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0098794 | Cellular component | postsynapse |
| GO_0005925 | Cellular component | focal adhesion |
| GO_0005829 | Cellular component | cytosol |
| GO_0042995 | Cellular component | cell projection |
| GO_0019901 | Molecular function | protein kinase binding |
| GO_0005525 | Molecular function | GTP binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003924 | Molecular function | GTPase activity |
| Gene name | RHOG |
| Protein name | Rho-related GTP-binding protein RhoG ARHG protein (Ras homolog gene family, member G (Rho G)) |
| Synonyms | ARHG hCG_16162 |
| Description | FUNCTION: Plays a role in immunological synaptic F-actin density and architecture organization . Regulates actin reorganization in lymphocytes, possibly through the modulation of Rac1 activity . Required for the formation of membrane ruffles during macropinocytosis . Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes . Binds phospholipids in an activation-dependent manner; thereby acting as an anchor for other proteins to the plasma membrane (PM) . Plays a role in exocytosis of cytotoxic granules (CG) by lymphocytes/Component of the exocytosis machinery in natural killer (NK) and CD8+ T cells . Promotes the docking of cytotoxic granules (CG) to the plasma membrane through the interaction with UNC13D . Involved in the cytotoxic activity of lymphocytes/primary CD8+ T cells . .; FUNCTION: (Microbial infection) In case of Salmonella enterica infection, activated by SopB and ARHGEF26/SGEF, which induces cytoskeleton rearrangements and promotes bacterial entry. . |
| Accessions | Q6ICQ8 ENST00000533217.1 ENST00000351018.5 ENST00000396978.1 ENST00000396979.1 P84095 |
