Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 10 studies | 48% ± 21% | |
| GABAergic neuron | 9 studies | 46% ± 23% | |
| oligodendrocyte | 9 studies | 29% ± 12% | |
| astrocyte | 8 studies | 30% ± 14% | |
| macrophage | 8 studies | 34% ± 11% | |
| microglial cell | 8 studies | 32% ± 12% | |
| oligodendrocyte precursor cell | 8 studies | 38% ± 13% | |
| retinal ganglion cell | 7 studies | 40% ± 13% | |
| retina horizontal cell | 6 studies | 38% ± 15% | |
| neuron | 5 studies | 40% ± 14% | |
| interneuron | 5 studies | 65% ± 18% | |
| endothelial cell | 4 studies | 44% ± 17% | |
| granule cell | 4 studies | 51% ± 10% | |
| pericyte | 4 studies | 29% ± 20% | |
| amacrine cell | 4 studies | 50% ± 16% | |
| GABAergic amacrine cell | 3 studies | 25% ± 6% | |
| OFF-bipolar cell | 3 studies | 23% ± 3% | |
| ON-bipolar cell | 3 studies | 25% ± 6% | |
| glycinergic amacrine cell | 3 studies | 32% ± 4% | |
| myeloid cell | 3 studies | 19% ± 1% | |
| hepatocyte | 3 studies | 68% ± 26% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 6552.35 | 2637 / 2642 | 99% | 11.96 | 700 / 705 |
| liver | 88% | 1336.03 | 200 / 226 | 70% | 2.92 | 283 / 406 |
| ovary | 98% | 1105.66 | 176 / 180 | 48% | 1.02 | 208 / 430 |
| uterus | 92% | 816.78 | 156 / 170 | 47% | 1.06 | 216 / 459 |
| bladder | 76% | 507.52 | 16 / 21 | 59% | 1.47 | 298 / 504 |
| prostate | 43% | 274.27 | 106 / 245 | 91% | 2.75 | 456 / 502 |
| intestine | 70% | 520.40 | 680 / 966 | 63% | 1.44 | 331 / 527 |
| breast | 62% | 486.46 | 283 / 459 | 67% | 1.92 | 744 / 1118 |
| skin | 77% | 657.85 | 1385 / 1809 | 44% | 1.02 | 206 / 472 |
| esophagus | 43% | 279.79 | 616 / 1445 | 75% | 2.01 | 137 / 183 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.04 | 1 / 1 |
| kidney | 35% | 239.74 | 31 / 89 | 62% | 1.55 | 555 / 901 |
| spleen | 93% | 874.06 | 223 / 241 | 0% | 0 | 0 / 0 |
| lung | 17% | 92.77 | 97 / 578 | 72% | 1.88 | 827 / 1155 |
| stomach | 26% | 189.76 | 95 / 359 | 59% | 1.31 | 169 / 286 |
| thymus | 45% | 316.69 | 294 / 653 | 39% | 0.75 | 238 / 605 |
| blood vessel | 83% | 658.33 | 1113 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 7% | 64.29 | 18 / 258 | 68% | 9.78 | 156 / 230 |
| pancreas | 2% | 13.63 | 8 / 328 | 71% | 1.67 | 127 / 178 |
| adipose | 71% | 532.77 | 860 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 40% | 0.73 | 18 / 45 |
| heart | 34% | 245.38 | 290 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 29% | 0.69 | 23 / 80 |
| muscle | 11% | 68.40 | 88 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.09 | 2 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0010468 | Biological process | regulation of gene expression |
| GO_0001701 | Biological process | in utero embryonic development |
| GO_0035264 | Biological process | multicellular organism growth |
| GO_0006886 | Biological process | intracellular protein transport |
| GO_0007155 | Biological process | cell adhesion |
| GO_0065003 | Biological process | protein-containing complex assembly |
| GO_0008088 | Biological process | axo-dendritic transport |
| GO_0007268 | Biological process | chemical synaptic transmission |
| GO_0099171 | Biological process | presynaptic modulation of chemical synaptic transmission |
| GO_0007626 | Biological process | locomotory behavior |
| GO_0007399 | Biological process | nervous system development |
| GO_0014051 | Biological process | gamma-aminobutyric acid secretion |
| GO_0014047 | Biological process | glutamate secretion |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0098685 | Cellular component | Schaffer collateral - CA1 synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0043197 | Cellular component | dendritic spine |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0048787 | Cellular component | presynaptic active zone membrane |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005829 | Cellular component | cytosol |
| GO_0008021 | Cellular component | synaptic vesicle |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0001540 | Molecular function | amyloid-beta binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | APBA1 |
| Protein name | Amyloid-beta A4 precursor protein-binding family A member 1 Amyloid beta precursor protein binding family A member 1 Amyloid beta precursor protein binding family A member 1 (Amyloid-beta A4 precursor protein-binding family A member 1) Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1) |
| Synonyms | MINT1 X11 |
| Description | FUNCTION: Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity). . |
| Accessions | ENST00000617471.3 ENST00000699288.1 Q02410 A0A8V8TPS8 ENST00000620509.2 ENST00000265381.7 [Q02410-1] A0A0D9SFA9 ENST00000470082.2 A0A0G2JMD7 |