DOCK10 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
macrophage	26 studies	29% ± 14%	Explore
natural killer cell	20 studies	27% ± 14%	Explore
CD8-positive, alpha-beta T cell	20 studies	26% ± 10%	Explore
CD4-positive, alpha-beta T cell	19 studies	29% ± 13%	Explore
T cell	18 studies	34% ± 17%	Explore
B cell	17 studies	26% ± 12%	Explore
oligodendrocyte	16 studies	83% ± 12%	Explore
oligodendrocyte precursor cell	16 studies	61% ± 20%	Explore
regulatory T cell	16 studies	26% ± 11%	Explore
mast cell	15 studies	44% ± 20%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	28% ± 11%	Explore
microglial cell	13 studies	63% ± 15%	Explore
dendritic cell	12 studies	43% ± 19%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	25% ± 11%	Explore
gamma-delta T cell	12 studies	24% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	25% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	10 studies	30% ± 15%	Explore
GABAergic neuron	10 studies	49% ± 18%	Explore
conventional dendritic cell	10 studies	26% ± 11%	Explore
myeloid cell	9 studies	34% ± 15%	Explore
mature NK T cell	8 studies	26% ± 12%	Explore
leukocyte	8 studies	46% ± 27%	Explore
mucosal invariant T cell	8 studies	26% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	22% ± 4%	Explore
non-classical monocyte	7 studies	23% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	35% ± 16%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	24% ± 6%	Explore
monocyte	7 studies	44% ± 17%	Explore
memory B cell	7 studies	17% ± 2%	Explore
interneuron	6 studies	47% ± 30%	Explore
retina horizontal cell	6 studies	63% ± 24%	Explore
innate lymphoid cell	6 studies	27% ± 15%	Explore
smooth muscle cell	6 studies	28% ± 7%	Explore
classical monocyte	5 studies	20% ± 1%	Explore
astrocyte	5 studies	47% ± 15%	Explore
endothelial cell	5 studies	31% ± 12%	Explore
glutamatergic neuron	5 studies	28% ± 11%	Explore
neuron	4 studies	30% ± 22%	Explore
lymphocyte	4 studies	61% ± 22%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	26% ± 6%	Explore
pericyte	4 studies	27% ± 11%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	67% ± 14%	Explore
GABAergic interneuron	3 studies	37% ± 13%	Explore
glial cell	3 studies	33% ± 17%	Explore
granule cell	3 studies	49% ± 29%	Explore
precursor B cell	3 studies	24% ± 2%	Explore
plasma cell	3 studies	27% ± 6%	Explore
mononuclear phagocyte	3 studies	30% ± 2%	Explore
glycinergic amacrine cell	3 studies	23% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	17% ± 2%	Explore
alveolar macrophage	3 studies	63% ± 8%	Explore
fibroblast	3 studies	23% ± 9%	Explore
group 3 innate lymphoid cell	3 studies	23% ± 5%	Explore
naive B cell	3 studies	24% ± 3%	Explore
plasmacytoid dendritic cell	3 studies	22% ± 7%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	17 studies	39% ± 18%	Explore
peripheral blood	8 studies	19% ± 3%	Explore
lung	4 studies	24% ± 7%	Explore
adipose	3 studies	19% ± 4%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	94%	2680.82	2472 / 2642	100%	28.02	702 / 705
skin	87%	1810.22	1573 / 1809	97%	20.97	456 / 472
breast	89%	892.67	408 / 459	94%	9.75	1046 / 1118
lung	99%	1874.19	575 / 578	81%	6.40	938 / 1155
thymus	88%	848.90	575 / 653	87%	6.82	529 / 605
adrenal gland	100%	1950.88	258 / 258	67%	4.89	155 / 230
kidney	78%	686.20	69 / 89	84%	8.68	757 / 901
ovary	100%	4274.76	180 / 180	40%	1.57	174 / 430
uterus	66%	585.31	113 / 170	67%	3.61	306 / 459
esophagus	59%	423.56	848 / 1445	69%	3.55	126 / 183
intestine	75%	1157.87	729 / 966	49%	2.68	258 / 527
stomach	45%	280.16	161 / 359	62%	3.73	177 / 286
bladder	62%	499.57	13 / 21	44%	2.78	224 / 504
spleen	100%	6973.86	241 / 241	0%	0	0 / 0
blood vessel	100%	3170.14	1332 / 1335	0%	0	0 / 0
adipose	97%	1215.72	1163 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	29.95	28 / 29
pancreas	13%	86.29	43 / 328	82%	5.74	146 / 178
peripheral blood	88%	3291.39	819 / 929	0%	0	0 / 0
prostate	41%	282.88	101 / 245	40%	1.70	202 / 502
tonsil	0%	0	0 / 0	80%	8.14	36 / 45
liver	23%	123.59	51 / 226	29%	1.42	117 / 406
eye	0%	0	0 / 0	49%	3.62	39 / 80
heart	15%	97.05	129 / 861	0%	0	0 / 0
muscle	2%	13.18	19 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1