DBN1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010644Biological processcell communication by electrical coupling
GO_0031915Biological processpositive regulation of synaptic plasticity
GO_0001701Biological processin utero embryonic development
GO_0010643Biological processcell communication by chemical coupling
GO_0061003Biological processpositive regulation of dendritic spine morphogenesis
GO_0061351Biological processneural precursor cell proliferation
GO_0050773Biological processregulation of dendrite development
GO_1902685Biological processpositive regulation of receptor localization to synapse
GO_0048699Biological processgeneration of neurons
GO_0051220Biological processcytoplasmic sequestering of protein
GO_0048168Biological processregulation of neuronal synaptic plasticity
GO_0007015Biological processactin filament organization
GO_0032507Biological processmaintenance of protein location in cell
GO_0098978Cellular componentglutamatergic synapse
GO_0005856Cellular componentcytoskeleton
GO_0030425Cellular componentdendrite
GO_0030863Cellular componentcortical cytoskeleton
GO_0015629Cellular componentactin cytoskeleton
GO_0014069Cellular componentpostsynaptic density
GO_0030426Cellular componentgrowth cone
GO_0099524Cellular componentpostsynaptic cytosol
GO_0005737Cellular componentcytoplasm
GO_0005921Cellular componentgap junction
GO_0045211Cellular componentpostsynaptic membrane
GO_0042641Cellular componentactomyosin
GO_0045296Molecular functioncadherin binding
GO_0005522Molecular functionprofilin binding
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding

IV. Literature review

[source]
Gene nameDBN1
Protein nameDrebrin (Developmentally-regulated brain protein)
Drebrin 1, isoform CRA_d (cDNA FLJ36806 fis, clone ASTRO1000165, highly similar to Drebrin)
Drebrin A
Drebrin 1
SynonymsD0S117E
hCG_2039393
DescriptionFUNCTION: Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections . Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS . Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity). Involved in memory-related synaptic plasticity in the hippocampus (By similarity). .

AccessionsQ16643
D6R9Q9
ENST00000292385.9 [Q16643-2]
D6R9W4
A0A2Z6ATB6
B3KSQ7
ENST00000506117.5
D6RCR4
D6RFI1
ENST00000393565.6 [Q16643-3]
ENST00000477391.6
ENST00000309007.9 [Q16643-1]
ENST00000512501.1
ENST00000514833.1