Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 16 studies | 71% ± 20% | |
| oligodendrocyte | 13 studies | 55% ± 14% | |
| oligodendrocyte precursor cell | 12 studies | 87% ± 17% | |
| glutamatergic neuron | 11 studies | 88% ± 13% | |
| GABAergic neuron | 10 studies | 80% ± 18% | |
| fibroblast | 10 studies | 32% ± 10% | |
| smooth muscle cell | 10 studies | 39% ± 17% | |
| endothelial cell | 9 studies | 39% ± 20% | |
| pericyte | 8 studies | 40% ± 19% | |
| neuron | 6 studies | 51% ± 27% | |
| amacrine cell | 5 studies | 45% ± 28% | |
| interneuron | 5 studies | 86% ± 12% | |
| capillary endothelial cell | 4 studies | 27% ± 14% | |
| Mueller cell | 4 studies | 82% ± 12% | |
| retinal ganglion cell | 4 studies | 63% ± 27% | |
| microglial cell | 4 studies | 48% ± 21% | |
| GABAergic amacrine cell | 3 studies | 86% ± 10% | |
| glycinergic amacrine cell | 3 studies | 69% ± 20% | |
| connective tissue cell | 3 studies | 20% ± 2% | |
| myofibroblast cell | 3 studies | 28% ± 9% | |
| granule cell | 3 studies | 76% ± 14% | |
| cardiac muscle cell | 3 studies | 20% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 3554.84 | 2642 / 2642 | 100% | 34.68 | 702 / 705 |
| adrenal gland | 93% | 1344.86 | 239 / 258 | 46% | 3.86 | 105 / 230 |
| uterus | 82% | 1149.56 | 140 / 170 | 29% | 1.40 | 131 / 459 |
| esophagus | 40% | 325.96 | 580 / 1445 | 64% | 2.38 | 117 / 183 |
| lung | 57% | 450.05 | 332 / 578 | 44% | 1.63 | 504 / 1155 |
| intestine | 82% | 807.41 | 793 / 966 | 18% | 0.40 | 96 / 527 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.04 | 1 / 1 |
| blood vessel | 90% | 2954.78 | 1199 / 1335 | 0% | 0 | 0 / 0 |
| breast | 72% | 771.06 | 329 / 459 | 17% | 0.59 | 185 / 1118 |
| stomach | 56% | 408.78 | 200 / 359 | 29% | 0.80 | 82 / 286 |
| adipose | 72% | 1450.32 | 868 / 1204 | 0% | 0 | 0 / 0 |
| skin | 50% | 560.61 | 907 / 1809 | 15% | 0.77 | 71 / 472 |
| bladder | 43% | 304.19 | 9 / 21 | 19% | 0.56 | 96 / 504 |
| prostate | 39% | 301.09 | 95 / 245 | 13% | 0.20 | 64 / 502 |
| ovary | 22% | 282.69 | 40 / 180 | 29% | 1.24 | 123 / 430 |
| kidney | 8% | 44.67 | 7 / 89 | 39% | 1.31 | 352 / 901 |
| thymus | 17% | 121.24 | 113 / 653 | 14% | 1.07 | 87 / 605 |
| heart | 28% | 179.87 | 242 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 0% | 1.41 | 1 / 328 | 27% | 0.55 | 48 / 178 |
| tonsil | 0% | 0 | 0 / 0 | 27% | 0.61 | 12 / 45 |
| muscle | 5% | 32.90 | 42 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.03 | 1 / 29 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.07 | 2 / 80 |
| liver | 0% | 0 | 0 / 226 | 2% | 0.03 | 7 / 406 |
| spleen | 1% | 5.33 | 2 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0098742 | Biological process | cell-cell adhesion via plasma-membrane adhesion molecules |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0007416 | Biological process | synapse assembly |
| GO_0001764 | Biological process | neuron migration |
| GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0005911 | Cellular component | cell-cell junction |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0030424 | Cellular component | axon |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0004930 | Molecular function | G protein-coupled receptor activity |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0030246 | Molecular function | carbohydrate binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ADGRL3 |
| Protein name | Adhesion G protein-coupled receptor L3 Uncharacterized protein LPHN3 Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3) |
| Synonyms | KIAA0768 LEC3 LPHN3 |
| Description | FUNCTION: Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells . Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. . |
| Accessions | E7EW95 E7ES20 E7EUP0 H0Y9K5 ENST00000514996.5 ENST00000514591.5 [Q9HAR2-4] ENST00000506746.5 ENST00000507164.5 E7ENK1 ENST00000506700.5 ENST00000507625.5 E7EMR3 ENST00000508946.5 E7EVD6 E7EN28 ENST00000683033.1 ENST00000514157.5 ENST00000509896.5 ENST00000504896.5 E7ETE3 A0A804HKL8 ENST00000508693.5 ENST00000506720.5 ENST00000512091.6 [Q9HAR2-2] E7EX52 ENST00000502815.1 E7EUW2 Q9HAR2 E7ESV6 Q4W5J9 E9PBG4 ENST00000511324.5 |