ADGRL3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0098742Biological processcell-cell adhesion via plasma-membrane adhesion molecules
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007416Biological processsynapse assembly
GO_0001764Biological processneuron migration
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0007166Biological processcell surface receptor signaling pathway
GO_0005911Cellular componentcell-cell junction
GO_0098978Cellular componentglutamatergic synapse
GO_0030424Cellular componentaxon
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0005509Molecular functioncalcium ion binding
GO_0030246Molecular functioncarbohydrate binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameADGRL3
Protein nameAdhesion G protein-coupled receptor L3
Uncharacterized protein LPHN3
Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3)
SynonymsKIAA0768
LEC3
LPHN3
DescriptionFUNCTION: Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells . Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. .

AccessionsE7EW95
E7ES20
E7EUP0
H0Y9K5
ENST00000514996.5
ENST00000514591.5 [Q9HAR2-4]
ENST00000506746.5
ENST00000507164.5
E7ENK1
ENST00000506700.5
ENST00000507625.5
E7EMR3
ENST00000508946.5
E7EVD6
E7EN28
ENST00000683033.1
ENST00000514157.5
ENST00000509896.5
ENST00000504896.5
E7ETE3
A0A804HKL8
ENST00000508693.5
ENST00000506720.5
ENST00000512091.6 [Q9HAR2-2]
E7EX52
ENST00000502815.1
E7EUW2
Q9HAR2
E7ESV6
Q4W5J9
E9PBG4
ENST00000511324.5