CACNG7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0043488Biological processregulation of mRNA stability
GO_1903861Biological processpositive regulation of dendrite extension
GO_0098970Biological processpostsynaptic neurotransmitter receptor diffusion trapping
GO_0099590Biological processneurotransmitter receptor internalization
GO_2000311Biological processregulation of AMPA receptor activity
GO_0098943Biological processneurotransmitter receptor transport, postsynaptic endosome to lysosome
GO_0051968Biological processpositive regulation of synaptic transmission, glutamatergic
GO_0019226Biological processtransmission of nerve impulse
GO_0099645Biological processneurotransmitter receptor localization to postsynaptic specialization membrane
GO_0006816Biological processcalcium ion transport
GO_0070588Biological processcalcium ion transmembrane transport
GO_0098978Cellular componentglutamatergic synapse
GO_0098839Cellular componentpostsynaptic density membrane
GO_0005886Cellular componentplasma membrane
GO_1990454Cellular componentL-type voltage-gated calcium channel complex
GO_0005769Cellular componentearly endosome
GO_0032281Cellular componentAMPA glutamate receptor complex
GO_0043025Cellular componentneuronal cell body
GO_0005891Cellular componentvoltage-gated calcium channel complex
GO_0044300Cellular componentcerebellar mossy fiber
GO_0005246Molecular functioncalcium channel regulator activity
GO_0005245Molecular functionvoltage-gated calcium channel activity
GO_0016247Molecular functionchannel regulator activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCACNG7
Protein nameVoltage-dependent calcium channel gamma-7 subunit (Neuronal voltage-gated calcium channel gamma-7 subunit) (Transmembrane AMPAR regulatory protein gamma-7) (TARP gamma-7)
Voltage-dependent calcium channel gamma-7 subunit
Synonyms
DescriptionFUNCTION: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit . Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity only for GRIA1 and GRIA2 . .

FUNCTION: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. .

AccessionsP62955
ENST00000391766.1
ENST00000391767.6
A0A0C4DFY2
ENST00000222212.6