DRD1 | OmnibusX

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DRD1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	96%	136.83	236 / 245	42%	0.95	213 / 502
brain	86%	1388.70	2265 / 2642	40%	1.75	284 / 705
bladder	81%	148.95	17 / 21	29%	1.38	147 / 504
lung	88%	146.92	508 / 578	21%	0.73	241 / 1155
ureter	0%	0	0 / 0	100%	2.80	1 / 1
uterus	68%	49.59	115 / 170	12%	0.80	54 / 459
adrenal gland	65%	77.34	167 / 258	9%	0.33	20 / 230
liver	56%	65.88	126 / 226	14%	0.75	58 / 406
adipose	70%	62.04	838 / 1204	0%	0	0 / 0
intestine	51%	37.65	493 / 966	18%	0.64	93 / 527
blood vessel	64%	54.47	861 / 1335	0%	0	0 / 0
stomach	43%	29.49	153 / 359	21%	0.81	59 / 286
breast	52%	40.14	238 / 459	8%	0.35	86 / 1118
esophagus	26%	15.38	382 / 1445	23%	1.10	42 / 183
thymus	43%	22.61	279 / 653	5%	0.31	29 / 605
pancreas	3%	1.06	9 / 328	41%	1.68	73 / 178
kidney	29%	26.24	26 / 89	8%	0.20	72 / 901
ovary	24%	13.94	43 / 180	3%	0.08	12 / 430
spleen	23%	9.62	56 / 241	0%	0	0 / 0
skin	10%	4.07	178 / 1809	2%	0.04	8 / 472
tonsil	0%	0	0 / 0	11%	0.65	5 / 45
eye	0%	0	0 / 0	3%	0.18	2 / 80
muscle	1%	0.48	7 / 803	0%	0	0 / 0
heart	1%	0.26	6 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007628	Biological process	adult walking behavior
GO_0007625	Biological process	grooming behavior
GO_0071880	Biological process	adenylate cyclase-activating adrenergic receptor signaling pathway
GO_0051968	Biological process	positive regulation of synaptic transmission, glutamatergic
GO_0046959	Biological process	habituation
GO_0021853	Biological process	cerebral cortex GABAergic interneuron migration
GO_0051584	Biological process	regulation of dopamine uptake involved in synaptic transmission
GO_0099010	Biological process	modification of postsynaptic structure
GO_2001224	Biological process	positive regulation of neuron migration
GO_0042053	Biological process	regulation of dopamine metabolic process
GO_0007191	Biological process	adenylate cyclase-activating dopamine receptor signaling pathway
GO_0021542	Biological process	dentate gyrus development
GO_0042417	Biological process	dopamine metabolic process
GO_0001932	Biological process	regulation of protein phosphorylation
GO_0060158	Biological process	phospholipase C-activating dopamine receptor signaling pathway
GO_0021756	Biological process	striatum development
GO_0043410	Biological process	positive regulation of MAPK cascade
GO_0060291	Biological process	long-term synaptic potentiation
GO_0060292	Biological process	long-term synaptic depression
GO_0008542	Biological process	visual learning
GO_0015872	Biological process	dopamine transport
GO_0007190	Biological process	activation of adenylate cyclase activity
GO_0071870	Biological process	cellular response to catecholamine stimulus
GO_0042711	Biological process	maternal behavior
GO_0030335	Biological process	positive regulation of cell migration
GO_0019228	Biological process	neuronal action potential
GO_0099171	Biological process	presynaptic modulation of chemical synaptic transmission
GO_0006606	Biological process	protein import into nucleus
GO_0001661	Biological process	conditioned taste aversion
GO_0043268	Biological process	positive regulation of potassium ion transport
GO_0007189	Biological process	adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0007187	Biological process	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO_0001662	Biological process	behavioral fear response
GO_0001963	Biological process	synaptic transmission, dopaminergic
GO_0001659	Biological process	temperature homeostasis
GO_0007613	Biological process	memory
GO_0007617	Biological process	mating behavior
GO_0001975	Biological process	response to amphetamine
GO_0014002	Biological process	astrocyte development
GO_0019226	Biological process	transmission of nerve impulse
GO_0051281	Biological process	positive regulation of release of sequestered calcium ion into cytosol
GO_0007416	Biological process	synapse assembly
GO_0009410	Biological process	response to xenobiotic stimulus
GO_0035106	Biological process	operant conditioning
GO_0046323	Biological process	glucose import
GO_0048148	Biological process	behavioral response to cocaine
GO_0042311	Biological process	vasodilation
GO_0060134	Biological process	prepulse inhibition
GO_0046960	Biological process	sensitization
GO_0007212	Biological process	G protein-coupled dopamine receptor signaling pathway
GO_0030432	Biological process	peristalsis
GO_0035249	Biological process	synaptic transmission, glutamatergic
GO_0098978	Cellular component	glutamatergic synapse
GO_0097648	Cellular component	G protein-coupled receptor complex
GO_0005886	Cellular component	plasma membrane
GO_0043197	Cellular component	dendritic spine
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0045211	Cellular component	postsynaptic membrane
GO_0042734	Cellular component	presynaptic membrane
GO_0060170	Cellular component	ciliary membrane
GO_0098982	Cellular component	GABA-ergic synapse
GO_0097730	Cellular component	non-motile cilium
GO_0005929	Cellular component	cilium
GO_0005634	Cellular component	nucleus
GO_0032795	Molecular function	heterotrimeric G-protein binding
GO_0004930	Molecular function	G protein-coupled receptor activity
GO_0001965	Molecular function	G-protein alpha-subunit binding
GO_0004952	Molecular function	dopamine neurotransmitter receptor activity
GO_1990763	Molecular function	arrestin family protein binding
GO_0001588	Molecular function	dopamine neurotransmitter receptor activity, coupled via Gs
GO_0035240	Molecular function	dopamine binding
GO_0005515	Molecular function	protein binding

Gene name	DRD1
Protein name	D(1A) dopamine receptor (Dopamine D1 receptor)
Synonyms
Description	FUNCTION: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. FUNCTION: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. .
Accessions	ENST00000393752.3 P21728 Q6FH34

DRD1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review