I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 5 studies | 41% ± 23% | |
| GABAergic neuron | 4 studies | 40% ± 12% | |
| interneuron | 3 studies | 27% ± 8% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 5 studies | 41% ± 23% | |
| GABAergic neuron | 4 studies | 40% ± 12% | |
| interneuron | 3 studies | 27% ± 8% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 35% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 95% | 4829.10 | 2516 / 2642 | 96% | 14.19 | 675 / 705 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.06 | 1 / 1 |
| ovary | 0% | 0 | 0 / 180 | 87% | 6.19 | 374 / 430 |
| adrenal gland | 1% | 3.71 | 2 / 258 | 86% | 5.70 | 197 / 230 |
| lymph node | 0% | 0 | 0 / 0 | 66% | 3.51 | 19 / 29 |
| spleen | 55% | 261.06 | 133 / 241 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 45% | 1.92 | 36 / 80 |
| esophagus | 0% | 0 | 0 / 1445 | 37% | 1.25 | 68 / 183 |
| thymus | 0% | 1.49 | 3 / 653 | 36% | 1.01 | 219 / 605 |
| pancreas | 2% | 8.97 | 8 / 328 | 33% | 1.29 | 59 / 178 |
| uterus | 0% | 0 | 0 / 170 | 29% | 1.16 | 135 / 459 |
| tonsil | 0% | 0 | 0 / 0 | 24% | 1.66 | 11 / 45 |
| breast | 0% | 0 | 0 / 459 | 21% | 0.72 | 238 / 1118 |
| bladder | 0% | 0 | 0 / 21 | 18% | 0.50 | 92 / 504 |
| skin | 0% | 0 | 0 / 1809 | 18% | 0.59 | 85 / 472 |
| lung | 0% | 0 | 0 / 578 | 18% | 0.65 | 205 / 1155 |
| stomach | 0% | 0 | 0 / 359 | 17% | 0.71 | 49 / 286 |
| intestine | 1% | 2.45 | 7 / 966 | 12% | 0.29 | 63 / 527 |
| kidney | 2% | 7.42 | 2 / 89 | 8% | 0.22 | 73 / 901 |
| liver | 0% | 0 | 0 / 226 | 6% | 0.18 | 26 / 406 |
| prostate | 0% | 0 | 0 / 245 | 3% | 0.10 | 17 / 502 |
| peripheral blood | 1% | 2.23 | 6 / 929 | 0% | 0 | 0 / 0 |
| adipose | 0% | 1.14 | 4 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.56 | 2 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0098962 | Biological process | regulation of postsynaptic neurotransmitter receptor activity |
| GO_0050804 | Biological process | modulation of chemical synaptic transmission |
| GO_0099563 | Biological process | modification of synaptic structure |
| GO_0023052 | Biological process | signaling |
| GO_0099572 | Cellular component | postsynaptic specialization |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0014069 | Cellular component | postsynaptic density |
| GO_0031594 | Cellular component | neuromuscular junction |
| GO_0098981 | Cellular component | cholinergic synapse |
| GO_0001540 | Molecular function | amyloid-beta binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0060090 | Molecular function | molecular adaptor activity |
| Gene name | DLGAP3 |
| Protein name | Disks large-associated protein 3 (DAP-3) (PSD-95/SAP90-binding protein 3) (SAP90/PSD-95-associated protein 3) (SAPAP3) DLGAP3 protein |
| Synonyms | DAP3 |
| Description | FUNCTION: May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. |
| Accessions | A4QMX6 ENST00000373347.6 O95886 ENST00000235180.4 A4FUA4 |
