NETO2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0098696Biological processregulation of neurotransmitter receptor localization to postsynaptic specialization membrane
GO_0099645Biological processneurotransmitter receptor localization to postsynaptic specialization membrane
GO_0098978Cellular componentglutamatergic synapse
GO_0098839Cellular componentpostsynaptic density membrane
GO_0014069Cellular componentpostsynaptic density
GO_0035255Molecular functionionotropic glutamate receptor binding

IV. Literature review

[source]
Gene nameNETO2
Protein nameNETO2 protein
Neuropilin and tolloid-like protein 2 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2)
Neuropilin and tolloid like 2
SynonymsUNQ1926/PRO4401
BTCL2
DescriptionFUNCTION: Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission (By similarity). .

AccessionsENST00000563078.1
Q32NC3
ENST00000562435.6 [Q8NC67-1]
ENST00000303155.9 [Q8NC67-3]
H3BM37
ENST00000564667.1
ENST00000562559.5
H3BTE1
H3BSR0
Q8NC67