DBNL report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
B cell	34 studies	32% ± 13%	Explore
natural killer cell	25 studies	27% ± 8%	Explore
conventional dendritic cell	25 studies	35% ± 15%	Explore
non-classical monocyte	23 studies	37% ± 15%	Explore
macrophage	23 studies	27% ± 11%	Explore
classical monocyte	21 studies	32% ± 14%	Explore
CD8-positive, alpha-beta T cell	20 studies	25% ± 7%	Explore
plasmacytoid dendritic cell	19 studies	44% ± 13%	Explore
CD4-positive, alpha-beta T cell	19 studies	24% ± 8%	Explore
monocyte	18 studies	26% ± 8%	Explore
memory B cell	18 studies	31% ± 8%	Explore
naive B cell	18 studies	28% ± 6%	Explore
dendritic cell	17 studies	40% ± 21%	Explore
regulatory T cell	17 studies	26% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	27% ± 8%	Explore
T cell	12 studies	24% ± 6%	Explore
gamma-delta T cell	11 studies	25% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	28% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	24% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	23% ± 10%	Explore
platelet	9 studies	25% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	9 studies	21% ± 4%	Explore
endothelial cell	9 studies	27% ± 9%	Explore
mucosal invariant T cell	9 studies	21% ± 3%	Explore
myeloid cell	9 studies	29% ± 13%	Explore
mature NK T cell	8 studies	24% ± 7%	Explore
epithelial cell	8 studies	31% ± 15%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	26% ± 9%	Explore
precursor B cell	6 studies	37% ± 10%	Explore
basal cell	6 studies	26% ± 13%	Explore
T follicular helper cell	6 studies	20% ± 3%	Explore
plasma cell	5 studies	33% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	27% ± 4%	Explore
pericyte	5 studies	21% ± 5%	Explore
ciliated cell	5 studies	24% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	27% ± 7%	Explore
plasmablast	4 studies	46% ± 17%	Explore
secretory cell	4 studies	21% ± 5%	Explore
squamous epithelial cell	4 studies	41% ± 21%	Explore
mononuclear phagocyte	4 studies	36% ± 20%	Explore
exhausted T cell	4 studies	32% ± 10%	Explore
fibroblast	4 studies	29% ± 8%	Explore
immature B cell	4 studies	41% ± 18%	Explore
microglial cell	4 studies	24% ± 10%	Explore
alveolar macrophage	4 studies	20% ± 4%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	35% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	33% ± 10%	Explore
abnormal cell	4 studies	26% ± 5%	Explore
goblet cell	4 studies	21% ± 6%	Explore
pancreatic A cell	3 studies	18% ± 1%	Explore
hematopoietic precursor cell	3 studies	40% ± 15%	Explore
leukocyte	3 studies	33% ± 5%	Explore
megakaryocyte	3 studies	34% ± 13%	Explore
connective tissue cell	3 studies	27% ± 0%	Explore
myofibroblast cell	3 studies	19% ± 3%	Explore
smooth muscle cell	3 studies	23% ± 4%	Explore
pro-B cell	3 studies	29% ± 7%	Explore
endothelial cell of artery	3 studies	17% ± 2%	Explore
germinal center B cell	3 studies	43% ± 7%	Explore
intermediate monocyte	3 studies	47% ± 19%	Explore
GABAergic neuron	3 studies	21% ± 8%	Explore
glutamatergic neuron	3 studies	27% ± 8%	Explore
group 3 innate lymphoid cell	3 studies	28% ± 10%	Explore
T-helper 1 cell	3 studies	27% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	21% ± 3%	Explore
double negative thymocyte	3 studies	29% ± 11%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	29% ± 10%	Explore
lung	6 studies	28% ± 3%	Explore
brain	6 studies	20% ± 3%	Explore
lymph node	4 studies	26% ± 3%	Explore
bone marrow	3 studies	21% ± 4%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	12490.97	1445 / 1445	100%	35.44	183 / 183
kidney	100%	6227.43	89 / 89	100%	32.28	901 / 901
lung	100%	9218.64	578 / 578	100%	38.83	1155 / 1155
ovary	100%	4993.77	180 / 180	100%	23.93	430 / 430
prostate	100%	8353.53	245 / 245	100%	34.96	502 / 502
skin	100%	8086.59	1809 / 1809	100%	44.77	472 / 472
uterus	100%	7263.82	170 / 170	100%	40.22	459 / 459
breast	100%	6929.71	459 / 459	100%	34.21	1117 / 1118
thymus	100%	7510.49	653 / 653	100%	36.41	604 / 605
intestine	100%	7976.77	966 / 966	100%	36.58	526 / 527
stomach	100%	5816.50	359 / 359	100%	31.41	285 / 286
bladder	100%	7504.62	21 / 21	100%	39.94	502 / 504
brain	100%	5286.87	2631 / 2642	100%	37.96	705 / 705
pancreas	99%	3429.80	326 / 328	100%	40.47	178 / 178
liver	100%	3815.96	226 / 226	99%	19.90	403 / 406
adrenal gland	100%	5841.41	258 / 258	99%	29.54	228 / 230
adipose	100%	7173.21	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	38.37	80 / 80
lymph node	0%	0	0 / 0	100%	93.35	29 / 29
spleen	100%	17885.87	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	47.84	45 / 45
ureter	0%	0	0 / 0	100%	14.79	1 / 1
peripheral blood	100%	17346.70	928 / 929	0%	0	0 / 0
blood vessel	100%	7434.72	1333 / 1335	0%	0	0 / 0
heart	98%	3462.73	847 / 861	0%	0	0 / 0
muscle	85%	2406.83	684 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0