NRP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1901166Biological processneural crest cell migration involved in autonomic nervous system development
GO_0001525Biological processangiogenesis
GO_0003148Biological processoutflow tract septum morphogenesis
GO_0097491Biological processsympathetic neuron projection guidance
GO_1904835Biological processdorsal root ganglion morphogenesis
GO_0021675Biological processnerve development
GO_0010595Biological processpositive regulation of endothelial cell migration
GO_1990830Biological processcellular response to leukemia inhibitory factor
GO_0061551Biological processtrigeminal ganglion development
GO_0021612Biological processfacial nerve structural organization
GO_0007155Biological processcell adhesion
GO_0048846Biological processaxon extension involved in axon guidance
GO_0036486Biological processventral trunk neural crest cell migration
GO_0021828Biological processgonadotrophin-releasing hormone neuronal migration to the hypothalamus
GO_0038084Biological processvascular endothelial growth factor signaling pathway
GO_0021649Biological processvestibulocochlear nerve structural organization
GO_0050919Biological processnegative chemotaxis
GO_0021637Biological processtrigeminal nerve structural organization
GO_0061549Biological processsympathetic ganglion development
GO_0021785Biological processbranchiomotor neuron axon guidance
GO_0001938Biological processpositive regulation of endothelial cell proliferation
GO_0097490Biological processsympathetic neuron projection extension
GO_0071526Biological processsemaphorin-plexin signaling pathway
GO_0097374Biological processsensory neuron axon guidance
GO_1903375Biological processfacioacoustic ganglion development
GO_0007411Biological processaxon guidance
GO_0099175Biological processregulation of postsynapse organization
GO_0098978Cellular componentglutamatergic synapse
GO_0002116Cellular componentsemaphorin receptor complex
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0045211Cellular componentpostsynaptic membrane
GO_0030424Cellular componentaxon
GO_0017154Molecular functionsemaphorin receptor activity
GO_0008201Molecular functionheparin binding
GO_0005021Molecular functionvascular endothelial growth factor receptor activity
GO_0038023Molecular functionsignaling receptor activity
GO_0019955Molecular functioncytokine binding
GO_0019838Molecular functiongrowth factor binding
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameNRP2
Protein nameNeuropilin-2 (Vascular endothelial cell growth factor 165 receptor 2)
NRP2 protein (Neuropilin 2, isoform CRA_i)
Neuropilin 2 isoform B
Neuropilin 2
Neuropilin
SynonymsVEGF165R2
hCG_15204
DescriptionFUNCTION: High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.; FUNCTION: (Microbial infection) Acts as a receptor for human cytomegalovirus pentamer-dependent entry in epithelial and endothelial cells. .

AccessionsB7ZL68
ENST00000357785.10 [O60462-3]
ENST00000417189.5 [O60462-6]
Q96GU8
ENST00000412873.2 [O60462-2]
X5D7M1
C9JH98
ENST00000450507.5
O60462
ENST00000357118.8 [O60462-4]
ENST00000272849.7 [O60462-5]
ENST00000360409.7 [O60462-1]