Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 30 studies | 27% ± 10% | |
pericyte | 29 studies | 35% ± 13% | |
smooth muscle cell | 25 studies | 28% ± 10% | |
endothelial cell | 20 studies | 28% ± 11% | |
ciliated cell | 13 studies | 38% ± 20% | |
endothelial cell of lymphatic vessel | 12 studies | 28% ± 10% | |
connective tissue cell | 12 studies | 30% ± 7% | |
myofibroblast cell | 11 studies | 30% ± 12% | |
type I pneumocyte | 9 studies | 24% ± 5% | |
epithelial cell | 9 studies | 32% ± 15% | |
neuron | 7 studies | 46% ± 20% | |
glutamatergic neuron | 7 studies | 39% ± 22% | |
retinal cone cell | 7 studies | 38% ± 25% | |
renal alpha-intercalated cell | 6 studies | 43% ± 7% | |
retinal rod cell | 6 studies | 28% ± 10% | |
endothelial cell of vascular tree | 6 studies | 22% ± 4% | |
GABAergic neuron | 6 studies | 35% ± 20% | |
capillary endothelial cell | 5 studies | 21% ± 4% | |
vein endothelial cell | 5 studies | 19% ± 2% | |
astrocyte | 5 studies | 20% ± 7% | |
type II pneumocyte | 5 studies | 18% ± 3% | |
basal cell | 5 studies | 28% ± 6% | |
interneuron | 5 studies | 38% ± 22% | |
ionocyte | 4 studies | 28% ± 12% | |
pancreatic A cell | 4 studies | 25% ± 6% | |
type B pancreatic cell | 4 studies | 47% ± 16% | |
oligodendrocyte | 4 studies | 25% ± 8% | |
retinal ganglion cell | 4 studies | 74% ± 24% | |
amacrine cell | 4 studies | 40% ± 16% | |
adipocyte | 4 studies | 34% ± 21% | |
enteroendocrine cell | 4 studies | 35% ± 18% | |
squamous epithelial cell | 3 studies | 47% ± 21% | |
glomerular endothelial cell | 3 studies | 24% ± 2% | |
natural killer cell | 3 studies | 22% ± 4% | |
endothelial cell of artery | 3 studies | 21% ± 5% | |
retinal bipolar neuron | 3 studies | 46% ± 17% | |
OFF-bipolar cell | 3 studies | 52% ± 27% | |
GABAergic amacrine cell | 3 studies | 30% ± 12% | |
glycinergic amacrine cell | 3 studies | 24% ± 9% | |
retina horizontal cell | 3 studies | 28% ± 7% | |
Mueller cell | 3 studies | 29% ± 8% | |
rod bipolar cell | 3 studies | 31% ± 11% | |
mesothelial cell | 3 studies | 28% ± 16% | |
myoepithelial cell | 3 studies | 25% ± 5% | |
luminal cell of prostate epithelium | 3 studies | 24% ± 8% | |
goblet cell | 3 studies | 18% ± 3% | |
intestinal crypt stem cell | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 2334.34 | 180 / 180 | 98% | 81.14 | 420 / 430 |
thymus | 100% | 3361.56 | 653 / 653 | 98% | 53.76 | 590 / 605 |
intestine | 100% | 2805.94 | 964 / 966 | 98% | 70.40 | 515 / 527 |
brain | 100% | 6243.62 | 2640 / 2642 | 97% | 107.53 | 686 / 705 |
prostate | 99% | 2954.57 | 243 / 245 | 98% | 91.48 | 491 / 502 |
kidney | 100% | 2732.04 | 89 / 89 | 94% | 51.00 | 847 / 901 |
breast | 100% | 2301.87 | 459 / 459 | 93% | 57.14 | 1045 / 1118 |
adrenal gland | 95% | 1374.40 | 246 / 258 | 97% | 118.25 | 224 / 230 |
stomach | 97% | 1561.57 | 348 / 359 | 94% | 73.81 | 269 / 286 |
lung | 99% | 2203.64 | 571 / 578 | 90% | 49.04 | 1038 / 1155 |
uterus | 100% | 2673.63 | 170 / 170 | 87% | 61.90 | 400 / 459 |
skin | 95% | 2465.44 | 1711 / 1809 | 91% | 62.08 | 431 / 472 |
bladder | 100% | 2271.90 | 21 / 21 | 85% | 53.27 | 430 / 504 |
esophagus | 93% | 2369.02 | 1348 / 1445 | 91% | 43.02 | 167 / 183 |
liver | 89% | 1547.88 | 202 / 226 | 92% | 61.75 | 372 / 406 |
pancreas | 58% | 525.41 | 191 / 328 | 98% | 81.63 | 174 / 178 |
eye | 0% | 0 | 0 / 0 | 100% | 122.27 | 80 / 80 |
ureter | 0% | 0 | 0 / 0 | 100% | 151.63 | 1 / 1 |
blood vessel | 100% | 2614.64 | 1331 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 2626.63 | 1199 / 1204 | 0% | 0 | 0 / 0 |
heart | 99% | 2728.47 | 855 / 861 | 0% | 0 | 0 / 0 |
spleen | 98% | 1311.67 | 236 / 241 | 0% | 0 | 0 / 0 |
muscle | 96% | 1498.21 | 768 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 93% | 79.29 | 27 / 29 |
tonsil | 0% | 0 | 0 / 0 | 80% | 46.55 | 36 / 45 |
peripheral blood | 42% | 469.64 | 393 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007254 | Biological process | JNK cascade |
GO_0000045 | Biological process | autophagosome assembly |
GO_0010040 | Biological process | response to iron(II) ion |
GO_0010288 | Biological process | response to lead ion |
GO_0016236 | Biological process | macroautophagy |
GO_0009267 | Biological process | cellular response to starvation |
GO_0090650 | Biological process | cellular response to oxygen-glucose deprivation |
GO_0060395 | Biological process | SMAD protein signal transduction |
GO_0071280 | Biological process | cellular response to copper ion |
GO_0034198 | Biological process | cellular response to amino acid starvation |
GO_0000422 | Biological process | autophagy of mitochondrion |
GO_0038066 | Biological process | p38MAPK cascade |
GO_0097352 | Biological process | autophagosome maturation |
GO_0006995 | Biological process | cellular response to nitrogen starvation |
GO_0070301 | Biological process | cellular response to hydrogen peroxide |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005874 | Cellular component | microtubule |
GO_0044754 | Cellular component | autolysosome |
GO_0000421 | Cellular component | autophagosome membrane |
GO_0005829 | Cellular component | cytosol |
GO_0005770 | Cellular component | late endosome |
GO_0005776 | Cellular component | autophagosome |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0031090 | Cellular component | organelle membrane |
GO_0005543 | Molecular function | phospholipid binding |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0008429 | Molecular function | phosphatidylethanolamine binding |
GO_0005515 | Molecular function | protein binding |
Gene name | MAP1LC3A |
Protein name | Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A) (Autophagy-related ubiquitin-like modifier LC3 A) (MAP1 light chain 3-like protein 1) (MAP1A/MAP1B light chain 3 A) (MAP1A/MAP1B LC3 A) (Microtubule-associated protein 1 light chain 3 alpha) |
Synonyms | |
Description | FUNCTION: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) . While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation . Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover . . |
Accessions | ENST00000397709.1 [Q9H492-1] ENST00000374837.7 [Q9H492-2] ENST00000360668.8 [Q9H492-1] Q9H492 |