Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 5 studies | 34% ± 12% | |
endothelial cell | 4 studies | 24% ± 8% | |
ciliated cell | 4 studies | 23% ± 4% | |
astrocyte | 4 studies | 22% ± 4% | |
squamous epithelial cell | 3 studies | 39% ± 21% | |
respiratory goblet cell | 3 studies | 20% ± 5% | |
GABAergic neuron | 3 studies | 33% ± 7% | |
glutamatergic neuron | 3 studies | 35% ± 14% | |
basal cell | 3 studies | 31% ± 7% | |
goblet cell | 3 studies | 38% ± 28% | |
interneuron | 3 studies | 31% ± 17% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 25% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 3930.48 | 21 / 21 | 100% | 19.52 | 504 / 504 |
esophagus | 100% | 4741.44 | 1445 / 1445 | 100% | 19.26 | 183 / 183 |
intestine | 100% | 4065.38 | 966 / 966 | 100% | 23.05 | 527 / 527 |
pancreas | 100% | 4358.31 | 328 / 328 | 100% | 19.95 | 178 / 178 |
prostate | 100% | 4250.98 | 245 / 245 | 100% | 16.67 | 502 / 502 |
stomach | 100% | 3648.19 | 359 / 359 | 100% | 22.00 | 286 / 286 |
uterus | 100% | 3215.17 | 170 / 170 | 100% | 17.50 | 459 / 459 |
brain | 100% | 4567.14 | 2640 / 2642 | 100% | 19.47 | 705 / 705 |
breast | 100% | 3395.43 | 459 / 459 | 100% | 19.01 | 1117 / 1118 |
ovary | 100% | 2853.44 | 180 / 180 | 100% | 13.83 | 429 / 430 |
thymus | 100% | 4059.49 | 653 / 653 | 100% | 14.80 | 603 / 605 |
lung | 100% | 3407.56 | 576 / 578 | 100% | 16.85 | 1155 / 1155 |
skin | 100% | 6361.79 | 1809 / 1809 | 100% | 12.16 | 470 / 472 |
kidney | 100% | 3224.65 | 89 / 89 | 99% | 11.92 | 895 / 901 |
liver | 100% | 1851.12 | 226 / 226 | 99% | 8.31 | 401 / 406 |
adrenal gland | 100% | 2856.65 | 258 / 258 | 98% | 11.70 | 225 / 230 |
adipose | 100% | 2865.70 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 8.53 | 29 / 29 |
spleen | 100% | 5017.38 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 15.80 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.80 | 1 / 1 |
blood vessel | 100% | 3508.79 | 1334 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 4413.12 | 919 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 15.35 | 79 / 80 |
muscle | 98% | 2014.93 | 790 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 2750.29 | 844 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0015914 | Biological process | phospholipid transport |
GO_0120009 | Biological process | intermembrane lipid transfer |
GO_0032367 | Biological process | intracellular cholesterol transport |
GO_0010807 | Biological process | regulation of synaptic vesicle priming |
GO_0007009 | Biological process | plasma membrane organization |
GO_0006699 | Biological process | bile acid biosynthetic process |
GO_0030301 | Biological process | cholesterol transport |
GO_0051289 | Biological process | protein homotetramerization |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0005811 | Cellular component | lipid droplet |
GO_0009898 | Cellular component | cytoplasmic side of plasma membrane |
GO_0097038 | Cellular component | perinuclear endoplasmic reticulum |
GO_0005829 | Cellular component | cytosol |
GO_0015485 | Molecular function | cholesterol binding |
GO_0120020 | Molecular function | cholesterol transfer activity |
GO_0008526 | Molecular function | phosphatidylinositol transfer activity |
GO_0005546 | Molecular function | phosphatidylinositol-4,5-bisphosphate binding |
GO_0005515 | Molecular function | protein binding |
Gene name | OSBPL2 |
Protein name | Oxysterol-binding protein Oxysterol binding protein like 2 Oxysterol-binding protein-related protein 2 (ORP-2) (OSBP-related protein 2) |
Synonyms | hCG_40342 ORP2 KIAA0772 |
Description | FUNCTION: Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane . Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate . Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate . Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro) . . |
Accessions | Q9H1P3 ENST00000618509.4 ENST00000642957.1 ENST00000644702.1 ENST00000645426.1 A0A2R8YG95 ENST00000439951.6 ENST00000642516.1 ENST00000644189.1 A0A2R8YEX0 ENST00000645442.1 A0A2R8YG53 ENST00000448156.3 ENST00000643981.1 [Q9H1P3-1] E7ET92 A0A2R8YD49 ENST00000645520.1 ENST00000643412.1 [Q9H1P3-1] A0A2R8YFT0 ENST00000643174.1 A0A087WTV1 A0A087WVV0 A0A2R8Y5R1 A0A2R8Y690 A0A2R8Y362 A0A2R8Y703 ENST00000358053.3 [Q9H1P3-2] A0A2R8Y429 ENST00000644535.1 ENST00000646834.1 ENST00000622332.4 ENST00000646968.1 A0A2R8YG59 ENST00000644775.1 ENST00000313733.9 [Q9H1P3-1] A0A2R8Y5B9 ENST00000642714.1 ENST00000642932.1 H0Y7X4 A0A2R8YDU7 |