Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 16 studies | 44% ± 18% | |
smooth muscle cell | 14 studies | 33% ± 16% | |
fibroblast | 12 studies | 35% ± 16% | |
epithelial cell | 9 studies | 39% ± 14% | |
connective tissue cell | 8 studies | 51% ± 19% | |
basal cell | 7 studies | 32% ± 15% | |
myofibroblast cell | 7 studies | 43% ± 14% | |
renal alpha-intercalated cell | 6 studies | 62% ± 9% | |
pericyte | 6 studies | 41% ± 11% | |
neuron | 6 studies | 48% ± 25% | |
ionocyte | 5 studies | 39% ± 9% | |
kidney loop of Henle epithelial cell | 5 studies | 30% ± 7% | |
progenitor cell | 5 studies | 34% ± 20% | |
enteroendocrine cell | 5 studies | 35% ± 22% | |
abnormal cell | 5 studies | 27% ± 12% | |
glutamatergic neuron | 5 studies | 47% ± 24% | |
pancreatic A cell | 4 studies | 59% ± 24% | |
type B pancreatic cell | 4 studies | 68% ± 19% | |
kidney distal convoluted tubule epithelial cell | 4 studies | 47% ± 8% | |
epithelial cell of proximal tubule | 4 studies | 22% ± 3% | |
endothelial cell | 4 studies | 26% ± 14% | |
mesothelial cell | 4 studies | 55% ± 9% | |
astrocyte | 4 studies | 40% ± 15% | |
GABAergic neuron | 4 studies | 35% ± 9% | |
deuterosomal cell | 3 studies | 18% ± 3% | |
pancreatic D cell | 3 studies | 58% ± 28% | |
neural crest cell | 3 studies | 43% ± 14% | |
retinal ganglion cell | 3 studies | 85% ± 9% | |
amacrine cell | 3 studies | 49% ± 15% | |
Mueller cell | 3 studies | 49% ± 14% | |
oligodendrocyte precursor cell | 3 studies | 33% ± 7% | |
interneuron | 3 studies | 24% ± 8% | |
luminal hormone-sensing cell of mammary gland | 3 studies | 17% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 16166.67 | 2640 / 2642 | 100% | 345.37 | 703 / 705 |
prostate | 100% | 4161.53 | 244 / 245 | 99% | 113.95 | 497 / 502 |
thymus | 100% | 5331.44 | 651 / 653 | 97% | 117.04 | 588 / 605 |
ovary | 100% | 4043.32 | 180 / 180 | 97% | 132.51 | 415 / 430 |
kidney | 100% | 5903.97 | 89 / 89 | 84% | 75.57 | 757 / 901 |
bladder | 100% | 4234.14 | 21 / 21 | 83% | 106.51 | 420 / 504 |
adrenal gland | 92% | 2687.09 | 238 / 258 | 87% | 69.28 | 201 / 230 |
uterus | 99% | 4567.64 | 169 / 170 | 80% | 122.09 | 368 / 459 |
breast | 84% | 1887.10 | 385 / 459 | 88% | 96.82 | 985 / 1118 |
esophagus | 82% | 2729.02 | 1184 / 1445 | 77% | 111.10 | 141 / 183 |
intestine | 92% | 3008.91 | 891 / 966 | 50% | 34.03 | 262 / 527 |
lung | 54% | 1223.43 | 311 / 578 | 79% | 140.91 | 909 / 1155 |
skin | 42% | 2905.62 | 765 / 1809 | 88% | 86.41 | 413 / 472 |
pancreas | 59% | 1265.21 | 193 / 328 | 70% | 48.96 | 124 / 178 |
stomach | 55% | 2226.41 | 196 / 359 | 49% | 33.16 | 139 / 286 |
muscle | 100% | 12805.63 | 803 / 803 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 57.26 | 1 / 1 |
blood vessel | 100% | 7987.83 | 1330 / 1335 | 0% | 0 | 0 / 0 |
adipose | 78% | 1773.38 | 945 / 1204 | 0% | 0 | 0 / 0 |
heart | 75% | 1868.12 | 649 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 58% | 65.14 | 26 / 45 |
eye | 0% | 0 | 0 / 0 | 53% | 25.45 | 42 / 80 |
liver | 7% | 128.00 | 16 / 226 | 12% | 8.08 | 49 / 406 |
spleen | 18% | 314.51 | 43 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 7% | 3.15 | 2 / 29 |
peripheral blood | 3% | 90.98 | 29 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030837 | Biological process | negative regulation of actin filament polymerization |
GO_0030838 | Biological process | positive regulation of actin filament polymerization |
GO_0032781 | Biological process | positive regulation of ATP-dependent activity |
GO_0030833 | Biological process | regulation of actin filament polymerization |
GO_0051496 | Biological process | positive regulation of stress fiber assembly |
GO_0033138 | Biological process | positive regulation of peptidyl-serine phosphorylation |
GO_0032233 | Biological process | positive regulation of actin filament bundle assembly |
GO_0030036 | Biological process | actin cytoskeleton organization |
GO_0098885 | Biological process | modification of postsynaptic actin cytoskeleton |
GO_0050821 | Biological process | protein stabilization |
GO_0099171 | Biological process | presynaptic modulation of chemical synaptic transmission |
GO_0010633 | Biological process | negative regulation of epithelial cell migration |
GO_1900028 | Biological process | negative regulation of ruffle assembly |
GO_2000300 | Biological process | regulation of synaptic vesicle exocytosis |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0098793 | Cellular component | presynapse |
GO_0005856 | Cellular component | cytoskeleton |
GO_0098685 | Cellular component | Schaffer collateral - CA1 synapse |
GO_0070062 | Cellular component | extracellular exosome |
GO_0098794 | Cellular component | postsynapse |
GO_0005737 | Cellular component | cytoplasm |
GO_0003785 | Molecular function | actin monomer binding |
GO_0005546 | Molecular function | phosphatidylinositol-4,5-bisphosphate binding |
GO_0005515 | Molecular function | protein binding |
GO_0003779 | Molecular function | actin binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
Gene name | PFN2 |
Protein name | Profilin Profilin-2 (Profilin II) Profilin 2 |
Synonyms | hCG_21343 |
Description | FUNCTION: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. |
Accessions | ENST00000475518.5 C9J5V8 C9J0J7 P35080 ENST00000461930.1 ENST00000649949.1 ENST00000498169.1 ENST00000461868.1 ENST00000490975.1 ENST00000239940.12 [P35080-1] ENST00000494827.5 F2Z3G0 ENST00000498307.5 C9J712 G5E9Q6 ENST00000460404.5 ENST00000423691.2 C9J2N0 ENST00000497148.5 ENST00000481767.5 ENST00000489155.1 ENST00000481275.5 ENST00000468323.5 ENST00000452853.6 [P35080-2] C9JQ45 |