Insufficient scRNA-seq data for expression of P2RX6 at single-cell level.
Insufficient scRNA-seq data for expression of P2RX6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 94% | 584.81 | 2491 / 2642 | 97% | 9.04 | 684 / 705 |
adrenal gland | 93% | 552.08 | 239 / 258 | 80% | 14.51 | 185 / 230 |
skin | 20% | 49.38 | 366 / 1809 | 87% | 6.73 | 409 / 472 |
muscle | 100% | 3151.54 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1576.65 | 241 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 95% | 6.98 | 76 / 80 |
bladder | 67% | 139.33 | 14 / 21 | 20% | 0.59 | 103 / 504 |
lung | 69% | 170.29 | 397 / 578 | 9% | 0.23 | 101 / 1155 |
kidney | 67% | 142.35 | 60 / 89 | 6% | 0.16 | 51 / 901 |
heart | 72% | 278.47 | 622 / 861 | 0% | 0 | 0 / 0 |
prostate | 62% | 144.04 | 152 / 245 | 7% | 0.13 | 34 / 502 |
ovary | 55% | 93.54 | 99 / 180 | 9% | 0.16 | 37 / 430 |
adipose | 52% | 180.94 | 622 / 1204 | 0% | 0 | 0 / 0 |
intestine | 42% | 70.62 | 409 / 966 | 4% | 0.13 | 22 / 527 |
uterus | 31% | 58.41 | 53 / 170 | 15% | 0.41 | 68 / 459 |
breast | 29% | 82.24 | 135 / 459 | 3% | 0.10 | 36 / 1118 |
blood vessel | 30% | 76.90 | 405 / 1335 | 0% | 0 | 0 / 0 |
esophagus | 13% | 21.71 | 187 / 1445 | 8% | 0.14 | 14 / 183 |
pancreas | 1% | 0.97 | 2 / 328 | 18% | 0.56 | 32 / 178 |
stomach | 11% | 17.47 | 39 / 359 | 4% | 0.07 | 12 / 286 |
liver | 5% | 7.71 | 11 / 226 | 7% | 0.27 | 30 / 406 |
tonsil | 0% | 0 | 0 / 0 | 11% | 0.17 | 5 / 45 |
thymus | 1% | 1.60 | 7 / 653 | 10% | 0.25 | 59 / 605 |
peripheral blood | 1% | 2.48 | 9 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0033198 | Biological process | response to ATP |
GO_0060079 | Biological process | excitatory postsynaptic potential |
GO_0007165 | Biological process | signal transduction |
GO_0035590 | Biological process | purinergic nucleotide receptor signaling pathway |
GO_0006936 | Biological process | muscle contraction |
GO_0070588 | Biological process | calcium ion transmembrane transport |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0043235 | Cellular component | receptor complex |
GO_0005886 | Cellular component | plasma membrane |
GO_0043197 | Cellular component | dendritic spine |
GO_0043025 | Cellular component | neuronal cell body |
GO_0005737 | Cellular component | cytoplasm |
GO_0030054 | Cellular component | cell junction |
GO_0098688 | Cellular component | parallel fiber to Purkinje cell synapse |
GO_0099634 | Cellular component | postsynaptic specialization membrane |
GO_0044877 | Molecular function | protein-containing complex binding |
GO_0004888 | Molecular function | transmembrane signaling receptor activity |
GO_0001614 | Molecular function | purinergic nucleotide receptor activity |
GO_0015267 | Molecular function | channel activity |
GO_0005524 | Molecular function | ATP binding |
GO_0004931 | Molecular function | extracellularly ATP-gated monoatomic cation channel activity |
Gene name | P2RX6 |
Protein name | p2RX6 protein Purinergic receptor P2X 6 P2X purinoceptor 6 (P2X6) (ATP receptor) (P2XM) (Purinergic receptor) (Purinergic receptor P2X-like 1) P2X purinoceptor |
Synonyms | P2RXL1 P2X6 hCG_41274 |
Description | FUNCTION: Receptor for ATP that acts as a ligand-gated ion channel. . FUNCTION: Receptor for ATP that acts as a ligand-gated ion channel. . |
Accessions | ENST00000401443.5 [O15547-2] ENST00000413302.7 [O15547-1] Q05BG9 H7C140 ENST00000442475.5 O15547 ENST00000422210.5 Q6P1Z3 ENST00000452228.5 H7C266 ENST00000432930.5 E7ES48 H7C2V4 |