ABHD17A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	32 studies	39% ± 19%	Explore
endothelial cell	22 studies	26% ± 11%	Explore
mature NK T cell	13 studies	30% ± 21%	Explore
gamma-delta T cell	13 studies	31% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	41% ± 22%	Explore
CD8-positive, alpha-beta T cell	12 studies	31% ± 23%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	35% ± 19%	Explore
capillary endothelial cell	9 studies	21% ± 4%	Explore
T cell	7 studies	25% ± 8%	Explore
CD4-positive, alpha-beta T cell	7 studies	34% ± 18%	Explore
oligodendrocyte	7 studies	26% ± 9%	Explore
B cell	6 studies	24% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	27% ± 13%	Explore
endothelial cell of artery	6 studies	27% ± 7%	Explore
epithelial cell	6 studies	29% ± 13%	Explore
leukocyte	5 studies	30% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	52% ± 20%	Explore
mucosal invariant T cell	5 studies	26% ± 7%	Explore
regulatory T cell	5 studies	25% ± 5%	Explore
classical monocyte	4 studies	34% ± 18%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	27% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	39% ± 15%	Explore
platelet	4 studies	31% ± 7%	Explore
innate lymphoid cell	4 studies	25% ± 7%	Explore
endothelial cell of lymphatic vessel	3 studies	16% ± 1%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	18% ± 3%	Explore
non-classical monocyte	3 studies	45% ± 18%	Explore
vein endothelial cell	3 studies	16% ± 1%	Explore
retinal ganglion cell	3 studies	32% ± 13%	Explore
myeloid cell	3 studies	27% ± 2%	Explore
monocyte	3 studies	20% ± 3%	Explore
ciliated cell	3 studies	24% ± 2%	Explore
CD4-positive helper T cell	3 studies	27% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	35% ± 17%	Explore
goblet cell	3 studies	19% ± 2%	Explore
macrophage	3 studies	21% ± 7%	Explore
T-helper 17 cell	3 studies	19% ± 5%	Explore
plasmacytoid dendritic cell	3 studies	18% ± 1%	Explore
basal cell	3 studies	30% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	7 studies	36% ± 15%	Explore
lung	4 studies	24% ± 5%	Explore
brain	4 studies	24% ± 6%	Explore
liver	4 studies	23% ± 5%	Explore
intestine	3 studies	20% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3630.42	1445 / 1445	100%	25.55	183 / 183
ovary	100%	2916.06	180 / 180	100%	24.85	430 / 430
brain	100%	6831.39	2640 / 2642	100%	30.86	705 / 705
thymus	100%	3468.59	652 / 653	100%	20.01	604 / 605
adrenal gland	100%	3221.19	258 / 258	100%	20.78	229 / 230
uterus	100%	3510.54	170 / 170	100%	19.20	457 / 459
kidney	100%	2960.88	89 / 89	99%	17.71	896 / 901
intestine	100%	3312.76	966 / 966	99%	19.29	524 / 527
prostate	100%	3929.31	245 / 245	99%	22.61	499 / 502
bladder	100%	3235.67	21 / 21	99%	19.59	500 / 504
stomach	100%	2557.97	359 / 359	99%	21.90	283 / 286
lung	100%	4265.70	577 / 578	99%	17.15	1143 / 1155
breast	100%	3384.19	459 / 459	99%	16.59	1104 / 1118
skin	100%	4811.55	1808 / 1809	99%	27.26	466 / 472
pancreas	99%	1717.71	324 / 328	99%	18.52	177 / 178
liver	100%	1598.01	226 / 226	97%	11.13	395 / 406
eye	0%	0	0 / 0	100%	24.25	80 / 80
lymph node	0%	0	0 / 0	100%	31.72	29 / 29
spleen	100%	5618.34	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	18.48	45 / 45
ureter	0%	0	0 / 0	100%	28.78	1 / 1
adipose	100%	3489.49	1202 / 1204	0%	0	0 / 0
peripheral blood	100%	5538.46	925 / 929	0%	0	0 / 0
heart	99%	2960.89	856 / 861	0%	0	0 / 0
blood vessel	99%	3196.61	1326 / 1335	0%	0	0 / 0
muscle	97%	2122.93	782 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_1905668	Biological process	positive regulation of protein localization to endosome
GO_1902817	Biological process	negative regulation of protein localization to microtubule
GO_0072657	Biological process	protein localization to membrane
GO_1900226	Biological process	negative regulation of NLRP3 inflammasome complex assembly
GO_0002084	Biological process	protein depalmitoylation
GO_0099175	Biological process	regulation of postsynapse organization
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0016607	Cellular component	nuclear speck
GO_0098978	Cellular component	glutamatergic synapse
GO_0010008	Cellular component	endosome membrane
GO_0098839	Cellular component	postsynaptic density membrane
GO_0055038	Cellular component	recycling endosome membrane
GO_0016020	Cellular component	membrane
GO_0005886	Cellular component	plasma membrane
GO_0043197	Cellular component	dendritic spine
GO_0098944	Cellular component	postsynaptic recycling endosome membrane
GO_0005515	Molecular function	protein binding
GO_0008474	Molecular function	palmitoyl-(protein) hydrolase activity

IV. Literature review

[source]

Gene name	ABHD17A
Protein name	Alpha/beta hydrolase domain-containing protein 17A (Abhydrolase domain-containing protein 17A) (EC 3.1.2.22) Abhydrolase domain containing 17A, depalmitoylase
Synonyms	FAM108A1 C19orf27
Description	FUNCTION: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins . Has depalmitoylating activity towards NRAS . Has depalmitoylating activity towards DLG4/PSD95 . May have depalmitoylating activity towards MAP6 (By similarity). .
Accessions	K7ENJ6 ENST00000592757.1 ENST00000250974.9 [Q96GS6-2] ENST00000292577.12 [Q96GS6-1] A0A7I2YQW9 ENST00000676686.1 [Q96GS6-1] ENST00000590661.1 Q96GS6 ENST00000677868.1 K7EQ25

ABHD17A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review