CACNG5 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CACNG5 at tissue level.

III. Associated gene sets

GO_0051968Biological processpositive regulation of synaptic transmission, glutamatergic
GO_0019226Biological processtransmission of nerve impulse
GO_0099590Biological processneurotransmitter receptor internalization
GO_2000311Biological processregulation of AMPA receptor activity
GO_0070588Biological processcalcium ion transmembrane transport
GO_0098970Biological processpostsynaptic neurotransmitter receptor diffusion trapping
GO_0098943Biological processneurotransmitter receptor transport, postsynaptic endosome to lysosome
GO_0098978Cellular componentglutamatergic synapse
GO_0098839Cellular componentpostsynaptic density membrane
GO_0032281Cellular componentAMPA glutamate receptor complex
GO_0014069Cellular componentpostsynaptic density
GO_0005245Molecular functionvoltage-gated calcium channel activity
GO_0015075Molecular functionmonoatomic ion transmembrane transporter activity
GO_0016247Molecular functionchannel regulator activity

IV. Literature review

[source]
Gene nameCACNG5
Protein nameVoltage-dependent calcium channel gamma-5 subunit (Neuronal voltage-gated calcium channel gamma-5 subunit) (Transmembrane AMPAR regulatory protein gamma-5) (TARP gamma-5)
Calcium voltage-gated channel auxiliary subunit gamma 5
Synonyms
DescriptionFUNCTION: Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity). .

AccessionsENST00000673855.1
Q9UF02
ENST00000307139.4
ENST00000533854.6
A0A669KBF6