Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 11 studies | 35% ± 17% | |
| GABAergic neuron | 7 studies | 31% ± 12% | |
| neuron | 5 studies | 24% ± 11% | |
| interneuron | 5 studies | 37% ± 19% | |
| granule cell | 4 studies | 41% ± 10% | |
| GABAergic interneuron | 3 studies | 25% ± 5% | |
| retina horizontal cell | 3 studies | 23% ± 5% | |
| pancreatic A cell | 3 studies | 44% ± 21% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 11 studies | 26% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 94% | 54834.95 | 2482 / 2642 | 84% | 90.31 | 593 / 705 |
| adrenal gland | 10% | 758.09 | 26 / 258 | 75% | 361.37 | 172 / 230 |
| pancreas | 1% | 58.49 | 4 / 328 | 44% | 21.07 | 79 / 178 |
| liver | 0% | 0 | 0 / 226 | 30% | 30.66 | 120 / 406 |
| ovary | 0% | 0 | 0 / 180 | 23% | 6.42 | 100 / 430 |
| lung | 0% | 0 | 0 / 578 | 11% | 9.97 | 123 / 1155 |
| intestine | 0% | 11.27 | 3 / 966 | 10% | 2.93 | 51 / 527 |
| stomach | 0% | 0 | 0 / 359 | 8% | 2.79 | 22 / 286 |
| esophagus | 0% | 0 | 0 / 1445 | 8% | 4.22 | 14 / 183 |
| breast | 0% | 0 | 0 / 459 | 4% | 4.94 | 46 / 1118 |
| bladder | 0% | 0 | 0 / 21 | 4% | 4.15 | 19 / 504 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.91 | 2 / 80 |
| uterus | 0% | 0 | 0 / 170 | 2% | 0.97 | 11 / 459 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 1.73 | 1 / 45 |
| kidney | 0% | 0 | 0 / 89 | 2% | 0.91 | 20 / 901 |
| prostate | 0% | 0 | 0 / 245 | 2% | 0.62 | 8 / 502 |
| thymus | 0% | 0 | 0 / 653 | 1% | 0.18 | 8 / 605 |
| skin | 0% | 0 | 0 / 1809 | 0% | 0.09 | 2 / 472 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0 | 0 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0031915 | Biological process | positive regulation of synaptic plasticity |
| GO_0031630 | Biological process | regulation of synaptic vesicle fusion to presynaptic active zone membrane |
| GO_0017157 | Biological process | regulation of exocytosis |
| GO_0016079 | Biological process | synaptic vesicle exocytosis |
| GO_0046928 | Biological process | regulation of neurotransmitter secretion |
| GO_0043303 | Biological process | mast cell degranulation |
| GO_0006904 | Biological process | vesicle docking involved in exocytosis |
| GO_0030154 | Biological process | cell differentiation |
| GO_0007399 | Biological process | nervous system development |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0043204 | Cellular component | perikaryon |
| GO_0043195 | Cellular component | terminal bouton |
| GO_0098794 | Cellular component | postsynapse |
| GO_0070033 | Cellular component | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex |
| GO_0070554 | Cellular component | synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex |
| GO_0030425 | Cellular component | dendrite |
| GO_0044305 | Cellular component | calyx of Held |
| GO_0005829 | Cellular component | cytosol |
| GO_0031201 | Cellular component | SNARE complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0017075 | Molecular function | syntaxin-1 binding |
| GO_0048306 | Molecular function | calcium-dependent protein binding |
| GO_0000149 | Molecular function | SNARE binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CPLX2 |
| Protein name | Complexin-2 (Complexin II) (CPX II) (Synaphin-1) Complexin-2 |
| Synonyms | |
| Description | FUNCTION: Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis (By similarity). . |
| Accessions | ENST00000393745.8 ENST00000515025.5 D6RI05 D6RBA5 ENST00000512824.5 ENST00000509837.5 ENST00000514150.5 ENST00000502265.5 D6R960 D6RDN3 Q6PUV4 D6RGY3 ENST00000359546.8 ENST00000515094.1 |
