NAPA | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	22 studies	28% ± 10%	Explore
classical monocyte	20 studies	30% ± 13%	Explore
non-classical monocyte	19 studies	36% ± 13%	Explore
plasmacytoid dendritic cell	18 studies	42% ± 18%	Explore
CD8-positive, alpha-beta T cell	18 studies	26% ± 9%	Explore
macrophage	17 studies	29% ± 11%	Explore
regulatory T cell	16 studies	27% ± 5%	Explore
conventional dendritic cell	15 studies	34% ± 15%	Explore
CD4-positive, alpha-beta T cell	15 studies	23% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	32% ± 8%	Explore
endothelial cell	13 studies	26% ± 9%	Explore
T cell	12 studies	23% ± 7%	Explore
monocyte	12 studies	27% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	28% ± 7%	Explore
B cell	11 studies	24% ± 7%	Explore
memory B cell	11 studies	21% ± 4%	Explore
naive B cell	11 studies	21% ± 5%	Explore
pericyte	11 studies	26% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	27% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	23% ± 4%	Explore
epithelial cell	10 studies	33% ± 17%	Explore
fibroblast	10 studies	25% ± 10%	Explore
gamma-delta T cell	10 studies	31% ± 11%	Explore
mature NK T cell	9 studies	26% ± 7%	Explore
smooth muscle cell	9 studies	24% ± 7%	Explore
mucosal invariant T cell	9 studies	25% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	9 studies	19% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	24% ± 5%	Explore
myeloid cell	8 studies	34% ± 10%	Explore
type II pneumocyte	8 studies	26% ± 14%	Explore
plasma cell	7 studies	31% ± 10%	Explore
platelet	7 studies	24% ± 10%	Explore
dendritic cell	7 studies	42% ± 19%	Explore
plasmablast	6 studies	43% ± 23%	Explore
basal cell	6 studies	31% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	27% ± 7%	Explore
glutamatergic neuron	5 studies	36% ± 23%	Explore
capillary endothelial cell	5 studies	20% ± 4%	Explore
ciliated cell	5 studies	28% ± 8%	Explore
T follicular helper cell	5 studies	24% ± 3%	Explore
abnormal cell	5 studies	31% ± 10%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	29% ± 6%	Explore
squamous epithelial cell	4 studies	33% ± 20%	Explore
exhausted T cell	4 studies	29% ± 2%	Explore
kidney loop of Henle epithelial cell	4 studies	23% ± 8%	Explore
neuron	4 studies	32% ± 9%	Explore
precursor B cell	4 studies	32% ± 9%	Explore
endothelial cell of lymphatic vessel	4 studies	22% ± 7%	Explore
myofibroblast cell	4 studies	26% ± 13%	Explore
type I pneumocyte	4 studies	26% ± 9%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	32% ± 2%	Explore
endothelial cell of vascular tree	4 studies	21% ± 5%	Explore
intermediate monocyte	4 studies	44% ± 14%	Explore
astrocyte	4 studies	23% ± 3%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	27% ± 4%	Explore
erythrocyte	4 studies	33% ± 18%	Explore
hematopoietic stem cell	4 studies	23% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	24% ± 6%	Explore
connective tissue cell	4 studies	22% ± 4%	Explore
secretory cell	3 studies	27% ± 7%	Explore
pancreatic A cell	3 studies	45% ± 12%	Explore
type B pancreatic cell	3 studies	55% ± 6%	Explore
leukocyte	3 studies	21% ± 5%	Explore
mononuclear phagocyte	3 studies	24% ± 7%	Explore
hematopoietic precursor cell	3 studies	26% ± 6%	Explore
innate lymphoid cell	3 studies	32% ± 4%	Explore
immature B cell	3 studies	30% ± 8%	Explore
pro-B cell	3 studies	24% ± 7%	Explore
GABAergic neuron	3 studies	36% ± 14%	Explore
oligodendrocyte precursor cell	3 studies	29% ± 9%	Explore
enteroendocrine cell	3 studies	29% ± 14%	Explore
goblet cell	3 studies	25% ± 4%	Explore
endothelial cell of artery	3 studies	18% ± 1%	Explore
alveolar macrophage	3 studies	23% ± 5%	Explore
group 3 innate lymphoid cell	3 studies	28% ± 7%	Explore
double negative thymocyte	3 studies	46% ± 22%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	32% ± 12%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	27% ± 6%	Explore
lung	7 studies	27% ± 6%	Explore
brain	5 studies	33% ± 12%	Explore
eye	4 studies	21% ± 4%	Explore
pancreas	3 studies	44% ± 9%	Explore
bone marrow	3 studies	21% ± 5%	Explore
kidney	3 studies	28% ± 7%	Explore
lymph node	3 studies	26% ± 9%	Explore
liver	3 studies	31% ± 18%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4310.82	1445 / 1445	100%	27.61	183 / 183
prostate	100%	4638.41	245 / 245	100%	49.81	502 / 502
skin	100%	5065.24	1809 / 1809	100%	32.94	472 / 472
ovary	100%	3350.22	180 / 180	100%	24.98	429 / 430
breast	100%	4323.75	459 / 459	100%	41.41	1115 / 1118
lung	100%	4147.57	578 / 578	100%	22.98	1151 / 1155
stomach	100%	3219.77	359 / 359	100%	28.90	285 / 286
adrenal gland	100%	6583.14	258 / 258	100%	55.02	229 / 230
pancreas	100%	2268.61	328 / 328	99%	25.70	177 / 178
intestine	100%	3578.02	966 / 966	99%	27.40	523 / 527
thymus	100%	3936.07	652 / 653	99%	27.60	600 / 605
bladder	100%	3617.19	21 / 21	99%	26.39	499 / 504
kidney	100%	4112.13	89 / 89	99%	24.56	891 / 901
uterus	100%	4492.99	170 / 170	99%	26.63	453 / 459
brain	99%	4769.22	2607 / 2642	100%	30.07	702 / 705
liver	100%	3385.66	225 / 226	98%	23.81	396 / 406
adipose	100%	3851.18	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	38.90	80 / 80
lymph node	0%	0	0 / 0	100%	25.31	29 / 29
muscle	100%	4998.66	803 / 803	0%	0	0 / 0
peripheral blood	100%	4505.50	929 / 929	0%	0	0 / 0
spleen	100%	3147.80	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	27.30	45 / 45
ureter	0%	0	0 / 0	100%	13.79	1 / 1
blood vessel	100%	3944.11	1334 / 1335	0%	0	0 / 0
heart	96%	3122.67	829 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0061025	Biological process	membrane fusion
GO_0006886	Biological process	intracellular protein transport
GO_0045176	Biological process	apical protein localization
GO_0030182	Biological process	neuron differentiation
GO_0010807	Biological process	regulation of synaptic vesicle priming
GO_0016082	Biological process	synaptic vesicle priming
GO_0006891	Biological process	intra-Golgi vesicle-mediated transport
GO_0007420	Biological process	brain development
GO_0035249	Biological process	synaptic transmission, glutamatergic
GO_0035494	Biological process	SNARE complex disassembly
GO_0098978	Cellular component	glutamatergic synapse
GO_0098793	Cellular component	presynapse
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0070062	Cellular component	extracellular exosome
GO_0005829	Cellular component	cytosol
GO_0070044	Cellular component	synaptobrevin 2-SNAP-25-syntaxin-1a complex
GO_0044877	Molecular function	protein-containing complex binding
GO_0005483	Molecular function	soluble NSF attachment protein activity
GO_0000149	Molecular function	SNARE binding
GO_0005515	Molecular function	protein binding
GO_0019905	Molecular function	syntaxin binding

IV. Literature review

[source]

Gene name	NAPA
Protein name	Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha) NSF attachment protein alpha
Synonyms	SNAPA
Description	FUNCTION: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane . . FUNCTION: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. . FUNCTION: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. .
Accessions	M0QZN5 M0R0Y2 ENST00000598615.5 M0R2M1 ENST00000594001.5 ENST00000263354.8 ENST00000601208.5 ENST00000594155.5 M0QZM9 M0R0I4 ENST00000597118.1 M0R058 M0R027 ENST00000595227.5 M0R031 ENST00000594217.5 ENST00000593761.5 P54920 M0R213 ENST00000597274.5

NAPA report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review