Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 22 studies | 39% ± 18% | |
astrocyte | 20 studies | 58% ± 18% | |
oligodendrocyte | 17 studies | 81% ± 17% | |
oligodendrocyte precursor cell | 17 studies | 72% ± 22% | |
microglial cell | 15 studies | 47% ± 17% | |
macrophage | 14 studies | 37% ± 19% | |
glutamatergic neuron | 13 studies | 79% ± 17% | |
mast cell | 12 studies | 34% ± 11% | |
GABAergic neuron | 11 studies | 78% ± 17% | |
fibroblast | 11 studies | 37% ± 11% | |
neuron | 10 studies | 60% ± 19% | |
smooth muscle cell | 10 studies | 35% ± 12% | |
pericyte | 9 studies | 40% ± 17% | |
adipocyte | 9 studies | 32% ± 9% | |
amacrine cell | 8 studies | 59% ± 27% | |
dendritic cell | 8 studies | 36% ± 13% | |
epithelial cell | 7 studies | 41% ± 18% | |
interneuron | 7 studies | 77% ± 23% | |
retinal ganglion cell | 7 studies | 77% ± 23% | |
myeloid cell | 7 studies | 28% ± 8% | |
retinal cone cell | 7 studies | 62% ± 28% | |
endothelial cell of lymphatic vessel | 7 studies | 37% ± 10% | |
B cell | 6 studies | 25% ± 8% | |
retina horizontal cell | 6 studies | 69% ± 25% | |
ciliated cell | 6 studies | 29% ± 11% | |
Mueller cell | 6 studies | 53% ± 26% | |
retinal rod cell | 6 studies | 61% ± 28% | |
retinal bipolar neuron | 5 studies | 51% ± 29% | |
cardiac muscle cell | 5 studies | 47% ± 11% | |
T cell | 5 studies | 26% ± 6% | |
monocyte | 5 studies | 34% ± 9% | |
type I pneumocyte | 5 studies | 33% ± 9% | |
type II pneumocyte | 5 studies | 32% ± 9% | |
glial cell | 4 studies | 48% ± 15% | |
granule cell | 4 studies | 79% ± 5% | |
retinal pigment epithelial cell | 4 studies | 46% ± 27% | |
CD8-positive, alpha-beta T cell | 4 studies | 18% ± 3% | |
mesothelial cell | 4 studies | 31% ± 10% | |
OFF-bipolar cell | 4 studies | 71% ± 23% | |
ON-bipolar cell | 4 studies | 71% ± 23% | |
club cell | 4 studies | 32% ± 12% | |
plasmacytoid dendritic cell | 4 studies | 24% ± 7% | |
classical monocyte | 3 studies | 17% ± 1% | |
hematopoietic precursor cell | 3 studies | 23% ± 8% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 75% ± 9% | |
GABAergic interneuron | 3 studies | 86% ± 3% | |
progenitor cell | 3 studies | 60% ± 22% | |
plasma cell | 3 studies | 35% ± 7% | |
CD16-negative, CD56-bright natural killer cell, human | 3 studies | 24% ± 6% | |
CD4-positive, alpha-beta T cell | 3 studies | 20% ± 1% | |
GABAergic amacrine cell | 3 studies | 87% ± 8% | |
glycinergic amacrine cell | 3 studies | 77% ± 8% | |
rod bipolar cell | 3 studies | 65% ± 24% | |
endothelial cell of vascular tree | 3 studies | 38% ± 18% | |
hepatocyte | 3 studies | 35% ± 12% | |
abnormal cell | 3 studies | 32% ± 13% | |
neural progenitor cell | 3 studies | 56% ± 23% | |
ependymal cell | 3 studies | 69% ± 17% | |
alveolar macrophage | 3 studies | 43% ± 9% | |
capillary endothelial cell | 3 studies | 31% ± 7% | |
natural killer cell | 3 studies | 29% ± 6% | |
respiratory goblet cell | 3 studies | 35% ± 16% | |
group 3 innate lymphoid cell | 3 studies | 20% ± 1% | |
lymphocyte | 3 studies | 37% ± 16% | |
muscle cell | 3 studies | 40% ± 32% | |
basal cell | 3 studies | 44% ± 24% | |
goblet cell | 3 studies | 42% ± 32% | |
leukocyte | 3 studies | 43% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 13320.99 | 2642 / 2642 | 100% | 59.79 | 705 / 705 |
esophagus | 100% | 2741.37 | 1440 / 1445 | 100% | 10.53 | 183 / 183 |
prostate | 100% | 2911.40 | 244 / 245 | 99% | 11.52 | 497 / 502 |
breast | 100% | 3422.83 | 458 / 459 | 98% | 14.11 | 1100 / 1118 |
lung | 99% | 3201.84 | 573 / 578 | 98% | 7.98 | 1133 / 1155 |
bladder | 100% | 2935.95 | 21 / 21 | 96% | 7.95 | 483 / 504 |
skin | 100% | 3223.43 | 1803 / 1809 | 95% | 17.36 | 450 / 472 |
intestine | 100% | 3785.19 | 965 / 966 | 95% | 7.94 | 500 / 527 |
thymus | 99% | 2786.15 | 647 / 653 | 95% | 7.59 | 577 / 605 |
adrenal gland | 100% | 3832.24 | 257 / 258 | 95% | 23.29 | 218 / 230 |
uterus | 100% | 3883.15 | 170 / 170 | 94% | 7.58 | 431 / 459 |
stomach | 97% | 2523.13 | 350 / 359 | 96% | 8.62 | 274 / 286 |
kidney | 97% | 2243.80 | 86 / 89 | 94% | 8.82 | 850 / 901 |
ovary | 100% | 4120.57 | 180 / 180 | 90% | 6.14 | 389 / 430 |
pancreas | 83% | 1437.82 | 272 / 328 | 96% | 7.77 | 170 / 178 |
liver | 38% | 525.68 | 87 / 226 | 62% | 3.44 | 253 / 406 |
spleen | 100% | 3046.25 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5126.04 | 1332 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 3112.98 | 1198 / 1204 | 0% | 0 | 0 / 0 |
muscle | 99% | 3737.10 | 797 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 8.58 | 28 / 29 |
heart | 90% | 2925.69 | 778 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 7.40 | 40 / 45 |
eye | 0% | 0 | 0 / 0 | 85% | 9.08 | 68 / 80 |
peripheral blood | 29% | 874.25 | 266 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0032886 | Biological process | regulation of microtubule-based process |
GO_0072659 | Biological process | protein localization to plasma membrane |
GO_1903690 | Biological process | negative regulation of wound healing, spreading of epidermal cells |
GO_0090091 | Biological process | positive regulation of extracellular matrix disassembly |
GO_0007052 | Biological process | mitotic spindle organization |
GO_0031110 | Biological process | regulation of microtubule polymerization or depolymerization |
GO_0007163 | Biological process | establishment or maintenance of cell polarity |
GO_0051895 | Biological process | negative regulation of focal adhesion assembly |
GO_0010470 | Biological process | regulation of gastrulation |
GO_0051301 | Biological process | cell division |
GO_0007020 | Biological process | microtubule nucleation |
GO_0034453 | Biological process | microtubule anchoring |
GO_0040001 | Biological process | establishment of mitotic spindle localization |
GO_0099187 | Biological process | presynaptic cytoskeleton organization |
GO_0007026 | Biological process | negative regulation of microtubule depolymerization |
GO_0090307 | Biological process | mitotic spindle assembly |
GO_0007030 | Biological process | Golgi organization |
GO_0006903 | Biological process | vesicle targeting |
GO_0010458 | Biological process | exit from mitosis |
GO_0000226 | Biological process | microtubule cytoskeleton organization |
GO_1904261 | Biological process | positive regulation of basement membrane assembly involved in embryonic body morphogenesis |
GO_0010717 | Biological process | regulation of epithelial to mesenchymal transition |
GO_0031023 | Biological process | microtubule organizing center organization |
GO_0045921 | Biological process | positive regulation of exocytosis |
GO_0010634 | Biological process | positive regulation of epithelial cell migration |
GO_0051497 | Biological process | negative regulation of stress fiber assembly |
GO_0032587 | Cellular component | ruffle membrane |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005876 | Cellular component | spindle microtubule |
GO_0005886 | Cellular component | plasma membrane |
GO_0005874 | Cellular component | microtubule |
GO_0072686 | Cellular component | mitotic spindle |
GO_0016020 | Cellular component | membrane |
GO_0005813 | Cellular component | centrosome |
GO_0000776 | Cellular component | kinetochore |
GO_0005815 | Cellular component | microtubule organizing center |
GO_0045180 | Cellular component | basal cortex |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0031252 | Cellular component | cell leading edge |
GO_0005925 | Cellular component | focal adhesion |
GO_0005802 | Cellular component | trans-Golgi network |
GO_0005829 | Cellular component | cytosol |
GO_0005828 | Cellular component | kinetochore microtubule |
GO_0005938 | Cellular component | cell cortex |
GO_0005881 | Cellular component | cytoplasmic microtubule |
GO_0005737 | Cellular component | cytoplasm |
GO_0051010 | Molecular function | microtubule plus-end binding |
GO_0002162 | Molecular function | dystroglycan binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CLASP2 |
Protein name | Cytoplasmic linker associated protein 2 CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (Protein Orbit homolog 2) (hOrbit2) Cytoplasmic linker associated protein 2 (cDNA FLJ33397 fis, clone BRACE2007937, highly similar to CLIP-associating protein 2) |
Synonyms | KIAA0627 hCG_1997378 |
Description | FUNCTION: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules . Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 . This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle . Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. . |
Accessions | ENST00000487553.5 ENST00000399362.8 ENST00000496954.2 ENST00000475576.1 H7C4X8 H7C4M5 ENST00000480013.6 [O75122-1] D6RBU8 ENST00000480385.1 ENST00000468888.6 ENST00000476251.1 ENST00000359576.9 [O75122-3] ENST00000313350.10 [O75122-2] C9J668 ENST00000333778.10 ENST00000635664.1 E7EW49 ENST00000485378.6 ENST00000461133.8 E7ENG2 ENST00000487200.5 ENST00000682230.1 O75122 J3KR49 H7C4I5 E3W994 A0A0U1RQI6 ENST00000650653.1 A0A804HJG7 H7C5M8 B3KR06 E7ERI8 |