SRCIN1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0061099Biological processnegative regulation of protein tyrosine kinase activity
GO_0098974Biological processpostsynaptic actin cytoskeleton organization
GO_0061001Biological processregulation of dendritic spine morphogenesis
GO_0006887Biological processexocytosis
GO_0034446Biological processsubstrate adhesion-dependent cell spreading
GO_0030334Biological processregulation of cell migration
GO_0061098Biological processpositive regulation of protein tyrosine kinase activity
GO_0098978Cellular componentglutamatergic synapse
GO_0015629Cellular componentactin cytoskeleton
GO_0030424Cellular componentaxon
GO_0098793Cellular componentpresynapse
GO_0030425Cellular componentdendrite
GO_0045202Cellular componentsynapse
GO_0014069Cellular componentpostsynaptic density
GO_0005737Cellular componentcytoplasm
GO_0005925Cellular componentfocal adhesion
GO_0019901Molecular functionprotein kinase binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSRCIN1
Protein nameSRC kinase signaling inhibitor 1 (SNAP-25-interacting protein) (SNIP) (p130Cas-associated protein) (p140Cap)
SRC kinase signaling inhibitor 1
SynonymsKIAA1684
P140
SNIP
DescriptionFUNCTION: Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance. .

AccessionsENST00000615049.4 [Q9C0H9-5]
ENST00000617146.5 [Q9C0H9-5]
Q9C0H9
ENST00000632117.1
A0A087WVV7
ENST00000631684.1
A0A590UJ70
A0A087WU33
ENST00000613927.1
ENST00000622519.4
ENST00000621492.4
ENST00000612431.1
ENST00000622190.4
ENST00000631564.1
A0A087X165
ENST00000632724.1
A0A087WTE6