Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 12 studies | 44% ± 19% | |
glutamatergic neuron | 8 studies | 31% ± 9% | |
GABAergic neuron | 6 studies | 28% ± 11% | |
interneuron | 5 studies | 42% ± 20% | |
retina horizontal cell | 5 studies | 21% ± 3% | |
neuron | 4 studies | 27% ± 6% | |
granule cell | 4 studies | 37% ± 12% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 11 studies | 34% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 10344.21 | 2635 / 2642 | 93% | 17.34 | 659 / 705 |
liver | 89% | 1310.94 | 202 / 226 | 64% | 3.53 | 259 / 406 |
breast | 60% | 754.91 | 276 / 459 | 86% | 9.24 | 959 / 1118 |
pancreas | 70% | 720.25 | 231 / 328 | 55% | 3.39 | 98 / 178 |
skin | 68% | 1058.24 | 1233 / 1809 | 50% | 2.55 | 235 / 472 |
intestine | 42% | 575.37 | 409 / 966 | 58% | 3.09 | 308 / 527 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.41 | 1 / 1 |
prostate | 28% | 255.63 | 68 / 245 | 70% | 3.07 | 349 / 502 |
bladder | 24% | 254.71 | 5 / 21 | 66% | 4.86 | 331 / 504 |
thymus | 2% | 20.73 | 16 / 653 | 83% | 6.18 | 502 / 605 |
adrenal gland | 10% | 169.54 | 27 / 258 | 68% | 13.76 | 157 / 230 |
stomach | 10% | 92.96 | 36 / 359 | 62% | 3.89 | 176 / 286 |
esophagus | 23% | 232.57 | 328 / 1445 | 46% | 3.04 | 85 / 183 |
lung | 13% | 143.38 | 77 / 578 | 47% | 2.95 | 540 / 1155 |
uterus | 11% | 112.61 | 18 / 170 | 43% | 2.52 | 197 / 459 |
ovary | 1% | 3.46 | 1 / 180 | 33% | 1.81 | 141 / 430 |
kidney | 1% | 8.87 | 1 / 89 | 26% | 1.25 | 231 / 901 |
eye | 0% | 0 | 0 / 0 | 25% | 0.78 | 20 / 80 |
adipose | 22% | 268.08 | 264 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 7% | 0.21 | 3 / 45 |
heart | 7% | 56.50 | 57 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 2.12 | 4 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0.97 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
GO_0061099 | Biological process | negative regulation of protein tyrosine kinase activity |
GO_0098974 | Biological process | postsynaptic actin cytoskeleton organization |
GO_0061001 | Biological process | regulation of dendritic spine morphogenesis |
GO_0006887 | Biological process | exocytosis |
GO_0034446 | Biological process | substrate adhesion-dependent cell spreading |
GO_0030334 | Biological process | regulation of cell migration |
GO_0061098 | Biological process | positive regulation of protein tyrosine kinase activity |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0030424 | Cellular component | axon |
GO_0098793 | Cellular component | presynapse |
GO_0030425 | Cellular component | dendrite |
GO_0045202 | Cellular component | synapse |
GO_0014069 | Cellular component | postsynaptic density |
GO_0005737 | Cellular component | cytoplasm |
GO_0005925 | Cellular component | focal adhesion |
GO_0019901 | Molecular function | protein kinase binding |
GO_0005515 | Molecular function | protein binding |
Gene name | SRCIN1 |
Protein name | SRC kinase signaling inhibitor 1 (SNAP-25-interacting protein) (SNIP) (p130Cas-associated protein) (p140Cap) SRC kinase signaling inhibitor 1 |
Synonyms | KIAA1684 P140 SNIP |
Description | FUNCTION: Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance. . |
Accessions | ENST00000615049.4 [Q9C0H9-5] ENST00000617146.5 [Q9C0H9-5] Q9C0H9 ENST00000632117.1 A0A087WVV7 ENST00000631684.1 A0A590UJ70 A0A087WU33 ENST00000613927.1 ENST00000622519.4 ENST00000621492.4 ENST00000612431.1 ENST00000622190.4 ENST00000631564.1 A0A087X165 ENST00000632724.1 A0A087WTE6 |