LPAR2 | OmnibusX

Name	Number of supported studies	Average coverage
CD4-positive, alpha-beta T cell	3 studies	16% ± 0%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of LPAR2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	2059.38	578 / 578	99%	25.22	1143 / 1155
thymus	100%	1469.10	653 / 653	99%	18.50	597 / 605
pancreas	100%	1152.63	328 / 328	98%	31.11	174 / 178
ovary	97%	738.51	174 / 180	100%	34.57	429 / 430
prostate	97%	1389.70	238 / 245	99%	35.60	498 / 502
breast	89%	627.76	410 / 459	99%	27.30	1104 / 1118
stomach	86%	1613.91	310 / 359	99%	25.03	283 / 286
bladder	81%	760.38	17 / 21	99%	39.10	498 / 504
intestine	74%	804.70	713 / 966	99%	26.93	524 / 527
kidney	89%	608.94	79 / 89	84%	10.97	753 / 901
uterus	68%	356.41	116 / 170	98%	30.47	449 / 459
esophagus	58%	448.28	835 / 1445	100%	25.66	183 / 183
skin	81%	872.16	1458 / 1809	73%	10.38	343 / 472
brain	53%	225.83	1389 / 2642	77%	10.56	546 / 705
lymph node	0%	0	0 / 0	100%	36.47	29 / 29
spleen	100%	5321.12	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	27.05	45 / 45
ureter	0%	0	0 / 0	100%	43.04	1 / 1
peripheral blood	100%	9975.38	928 / 929	0%	0	0 / 0
adipose	93%	630.91	1116 / 1204	0%	0	0 / 0
adrenal gland	37%	132.09	95 / 258	40%	4.20	93 / 230
eye	0%	0	0 / 0	71%	6.77	57 / 80
liver	38%	154.46	86 / 226	28%	8.18	114 / 406
blood vessel	49%	220.91	650 / 1335	0%	0	0 / 0
heart	16%	69.93	138 / 861	0%	0	0 / 0
muscle	1%	3.63	10 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0035025	Biological process	positive regulation of Rho protein signal transduction
GO_0007204	Biological process	positive regulation of cytosolic calcium ion concentration
GO_0043410	Biological process	positive regulation of MAPK cascade
GO_0007189	Biological process	adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0019222	Biological process	regulation of metabolic process
GO_0098978	Cellular component	glutamatergic synapse
GO_0009986	Cellular component	cell surface
GO_0048787	Cellular component	presynaptic active zone membrane
GO_0005886	Cellular component	plasma membrane
GO_0030139	Cellular component	endocytic vesicle
GO_0005737	Cellular component	cytoplasm
GO_0030165	Molecular function	PDZ domain binding
GO_0004930	Molecular function	G protein-coupled receptor activity
GO_0070915	Molecular function	lysophosphatidic acid receptor activity
GO_0005515	Molecular function	protein binding
GO_0008289	Molecular function	lipid binding

Gene name	LPAR2
Protein name	Alternative protein LPAR2 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 2 (LPA receptor 2) (LPA-2) (Lysophosphatidic acid receptor Edg-4)
Synonyms	EDG4 LPA2
Description	FUNCTION: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation. .
Accessions	ENST00000407877.8 ENST00000588461.1 ENST00000591042.1 ENST00000592061.1 Q9HBW0 K7EJJ9 ENST00000586703.1 ENST00000542587.5 K7ELJ6 K7ENG7 K7ER68 L8E990 ENST00000588233.1

LPAR2 report