CPLX1 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	8 studies	33% ± 18%	Explore
retinal ganglion cell	6 studies	68% ± 33%	Explore
GABAergic neuron	5 studies	45% ± 11%	Explore
neuron	4 studies	24% ± 7%	Explore
endothelial cell	4 studies	27% ± 6%	Explore
interneuron	4 studies	33% ± 15%	Explore
GABAergic interneuron	3 studies	18% ± 2%	Explore
endothelial cell of vascular tree	3 studies	19% ± 2%	Explore

Name	Number of supported studies	Average coverage
brain	6 studies	27% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	97%	12553.75	2573 / 2642	95%	60.28	672 / 705
prostate	79%	1289.37	194 / 245	97%	10.94	487 / 502
breast	93%	1792.48	429 / 459	81%	13.02	911 / 1118
adrenal gland	78%	1077.84	200 / 258	95%	37.19	218 / 230
ovary	48%	622.98	87 / 180	93%	14.21	398 / 430
uterus	85%	1635.77	145 / 170	47%	4.54	217 / 459
kidney	45%	531.47	40 / 89	71%	7.75	642 / 901
lung	48%	631.24	277 / 578	57%	6.02	655 / 1155
intestine	16%	189.30	150 / 966	83%	11.39	437 / 527
spleen	97%	2538.16	234 / 241	0%	0	0 / 0
esophagus	30%	398.69	429 / 1445	67%	7.72	123 / 183
stomach	11%	117.36	39 / 359	84%	12.91	239 / 286
eye	0%	0	0 / 0	93%	21.58	74 / 80
adipose	86%	1449.55	1041 / 1204	0%	0	0 / 0
pancreas	2%	17.96	6 / 328	80%	8.50	142 / 178
liver	9%	94.19	21 / 226	71%	12.30	287 / 406
bladder	29%	429.62	6 / 21	44%	4.16	223 / 504
thymus	39%	476.11	254 / 653	28%	4.91	171 / 605
heart	23%	269.70	202 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	22%	2.39	10 / 45
skin	4%	43.80	74 / 1809	18%	1.70	85 / 472
lymph node	0%	0	0 / 0	21%	2.40	6 / 29
blood vessel	15%	195.90	196 / 1335	0%	0	0 / 0
muscle	3%	27.71	21 / 803	0%	0	0 / 0
peripheral blood	0%	2.07	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0099145	Biological process	regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane
GO_0031630	Biological process	regulation of synaptic vesicle fusion to presynaptic active zone membrane
GO_0017157	Biological process	regulation of exocytosis
GO_0016079	Biological process	synaptic vesicle exocytosis
GO_0046928	Biological process	regulation of neurotransmitter secretion
GO_0006887	Biological process	exocytosis
GO_0007268	Biological process	chemical synaptic transmission
GO_0030073	Biological process	insulin secretion
GO_0098978	Cellular component	glutamatergic synapse
GO_0098685	Cellular component	Schaffer collateral - CA1 synapse
GO_0043204	Cellular component	perikaryon
GO_0043195	Cellular component	terminal bouton
GO_0098794	Cellular component	postsynapse
GO_0070554	Cellular component	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex
GO_0044305	Cellular component	calyx of Held
GO_0005829	Cellular component	cytosol
GO_0031201	Cellular component	SNARE complex
GO_0005326	Molecular function	neurotransmitter transmembrane transporter activity
GO_0000149	Molecular function	SNARE binding
GO_0005515	Molecular function	protein binding
GO_0019905	Molecular function	syntaxin binding

Gene name	CPLX1
Protein name	Complexin-1 Complexin-1 (Complexin I) (CPX I) (Synaphin-2)
Synonyms
Description	FUNCTION: Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles . Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse . Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior. .
Accessions	ENST00000504062.1 D6RI11 ENST00000505203.1 O14810 D6RAG3 ENST00000304062.11

CPLX1 report