ATP2B3 | OmnibusX

Name	Number of supported studies	Average coverage
GABAergic neuron	3 studies	30% ± 10%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of ATP2B3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	98%	2134.15	252 / 258	87%	31.29	199 / 230
brain	92%	3186.91	2436 / 2642	68%	6.42	478 / 705
eye	0%	0	0 / 0	31%	1.07	25 / 80
ovary	0%	0	0 / 180	14%	0.32	61 / 430
uterus	2%	7.70	3 / 170	9%	0.33	40 / 459
skin	0%	0.12	1 / 1809	8%	0.59	38 / 472
blood vessel	7%	20.97	95 / 1335	0%	0	0 / 0
intestine	7%	17.63	64 / 966	0%	0.03	2 / 527
kidney	2%	13.56	2 / 89	3%	0.12	24 / 901
tonsil	0%	0	0 / 0	2%	0.05	1 / 45
lung	0%	0	0 / 578	2%	0.08	21 / 1155
thymus	0%	1.17	1 / 653	2%	0.26	10 / 605
breast	0%	0	0 / 459	2%	0.07	20 / 1118
pancreas	0%	0	0 / 328	1%	0.06	2 / 178
esophagus	0%	0.88	5 / 1445	1%	0.01	1 / 183
stomach	1%	2.12	3 / 359	0%	0	0 / 286
bladder	0%	0	0 / 21	1%	0.09	4 / 504
liver	0%	0	0 / 226	0%	0.01	2 / 406
prostate	0%	0.86	1 / 245	0%	0	0 / 502
adipose	0%	0.29	1 / 1204	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
heart	0%	0	0 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0051480	Biological process	regulation of cytosolic calcium ion concentration
GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0099509	Biological process	regulation of presynaptic cytosolic calcium ion concentration
GO_1903779	Biological process	regulation of cardiac conduction
GO_1990034	Biological process	calcium ion export across plasma membrane
GO_1990032	Cellular component	parallel fiber
GO_0098978	Cellular component	glutamatergic synapse
GO_0005886	Cellular component	plasma membrane
GO_1903561	Cellular component	extracellular vesicle
GO_0042734	Cellular component	presynaptic membrane
GO_0098982	Cellular component	GABA-ergic synapse
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0098688	Cellular component	parallel fiber to Purkinje cell synapse
GO_0015085	Molecular function	calcium ion transmembrane transporter activity
GO_0005388	Molecular function	P-type calcium transporter activity
GO_0030165	Molecular function	PDZ domain binding
GO_0046872	Molecular function	metal ion binding
GO_0005524	Molecular function	ATP binding
GO_0005516	Molecular function	calmodulin binding
GO_0005515	Molecular function	protein binding
GO_0016887	Molecular function	ATP hydrolysis activity
GO_1905056	Molecular function	P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration

Gene name	ATP2B3
Protein name	ATPase plasma membrane Ca2+ transporting 3 Calcium-transporting ATPase (EC 7.2.2.10) PMCA3a Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3)
Synonyms
Description	FUNCTION: ATP-driven Ca(2+) ion pump involved in the maintenance of basal intracellular Ca(2+) levels at the presynaptic terminals . Uses ATP as an energy source to transport cytosolic Ca(2+) ions across the plasma membrane to the extracellular compartment . May counter-transport protons, but the mechanism and the stoichiometry of this Ca(2+)/H(+) exchange remains to be established (By similarity). . FUNCTION: Catalyzes the hydrolysis of ATP coupled with the transport of calcium. . FUNCTION: Catalyzes the hydrolysis of ATP coupled with the transport of calcium. . FUNCTION: Catalyzes the hydrolysis of ATP coupled with the transport of calcium. . FUNCTION: Catalyzes the hydrolysis of ATP coupled with the transport of calcium. .
Accessions	ENST00000359149.9 [Q16720-2] ENST00000705863.1 ENST00000370186.5 [Q16720-3] A0A804HKZ0 A0A994J4Z5 ENST00000705864.1 ENST00000496610.2 A1X4Q0 A1L3B5 ENST00000705862.1 ENST00000263519.5 [Q16720-1] ENST00000349466.6 [Q16720-1] ENST00000393842.5 [Q16720-6] Q16720 ENST00000683064.1 A0A994J7W3 A0A994J581 A0A994J5M1

ATP2B3 report