CLSTN2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1904862Biological processinhibitory synapse assembly
GO_0050806Biological processpositive regulation of synaptic transmission
GO_0008306Biological processassociative learning
GO_0007156Biological processhomophilic cell adhesion via plasma membrane adhesion molecules
GO_0051965Biological processpositive regulation of synapse assembly
GO_0098978Cellular componentglutamatergic synapse
GO_0009986Cellular componentcell surface
GO_0098839Cellular componentpostsynaptic density membrane
GO_0000139Cellular componentGolgi membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0045211Cellular componentpostsynaptic membrane
GO_0030425Cellular componentdendrite
GO_0005509Molecular functioncalcium ion binding

IV. Literature review

[source]
Gene nameCLSTN2
Protein nameCalsyntenin-2 (Alcadein-gamma) (Alc-gamma)
SynonymsCS2
DescriptionFUNCTION: Postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate synapse formation, and which is involved in learning and memory (By similarity). Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with neurexin-alpha at the presynaptic membrane (By similarity). .

AccessionsENST00000458420.7
Q9H4D0