Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 7 studies | 23% ± 8% | |
endothelial cell | 7 studies | 26% ± 7% | |
oligodendrocyte precursor cell | 6 studies | 38% ± 10% | |
adipocyte | 6 studies | 23% ± 6% | |
astrocyte | 6 studies | 34% ± 7% | |
fibroblast | 6 studies | 18% ± 3% | |
epithelial cell | 5 studies | 27% ± 11% | |
retinal cone cell | 5 studies | 18% ± 2% | |
macrophage | 5 studies | 30% ± 3% | |
glutamatergic neuron | 4 studies | 33% ± 18% | |
myeloid cell | 4 studies | 19% ± 2% | |
GABAergic neuron | 4 studies | 32% ± 17% | |
OFF-bipolar cell | 3 studies | 21% ± 4% | |
endothelial cell of lymphatic vessel | 3 studies | 19% ± 2% | |
smooth muscle cell | 3 studies | 22% ± 3% | |
mast cell | 3 studies | 20% ± 2% | |
interneuron | 3 studies | 39% ± 17% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 25% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 2804.56 | 180 / 180 | 100% | 23.08 | 430 / 430 |
prostate | 100% | 7170.59 | 245 / 245 | 100% | 33.33 | 502 / 502 |
uterus | 100% | 5414.42 | 170 / 170 | 100% | 22.70 | 459 / 459 |
breast | 100% | 6057.24 | 459 / 459 | 100% | 32.49 | 1116 / 1118 |
skin | 100% | 12238.28 | 1807 / 1809 | 99% | 21.66 | 469 / 472 |
intestine | 100% | 5194.67 | 964 / 966 | 99% | 16.92 | 524 / 527 |
esophagus | 99% | 3387.65 | 1431 / 1445 | 100% | 24.54 | 183 / 183 |
bladder | 100% | 6378.19 | 21 / 21 | 99% | 16.92 | 499 / 504 |
stomach | 99% | 2776.83 | 355 / 359 | 100% | 19.39 | 286 / 286 |
lung | 98% | 3321.90 | 568 / 578 | 100% | 21.83 | 1154 / 1155 |
thymus | 98% | 2425.32 | 642 / 653 | 99% | 15.49 | 600 / 605 |
pancreas | 99% | 2551.89 | 324 / 328 | 98% | 15.97 | 175 / 178 |
adrenal gland | 100% | 2362.65 | 258 / 258 | 91% | 12.79 | 209 / 230 |
liver | 83% | 1288.94 | 187 / 226 | 90% | 8.94 | 364 / 406 |
brain | 71% | 2356.96 | 1881 / 2642 | 100% | 15.26 | 702 / 705 |
kidney | 48% | 850.84 | 43 / 89 | 93% | 14.81 | 835 / 901 |
adipose | 100% | 6197.65 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 16.58 | 29 / 29 |
spleen | 100% | 2725.31 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 26.81 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 14.04 | 1 / 1 |
blood vessel | 100% | 5299.55 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 4879.43 | 796 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 95% | 13.82 | 76 / 80 |
heart | 89% | 2097.26 | 763 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 23% | 1168.25 | 216 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0002931 | Biological process | response to ischemia |
GO_0032869 | Biological process | cellular response to insulin stimulus |
GO_0071454 | Biological process | cellular response to anoxia |
GO_0061003 | Biological process | positive regulation of dendritic spine morphogenesis |
GO_1990416 | Biological process | cellular response to brain-derived neurotrophic factor stimulus |
GO_0140245 | Biological process | regulation of translation at postsynapse |
GO_0045807 | Biological process | positive regulation of endocytosis |
GO_0071277 | Biological process | cellular response to calcium ion |
GO_0006414 | Biological process | translational elongation |
GO_0071320 | Biological process | cellular response to cAMP |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_1990637 | Biological process | response to prolactin |
GO_0031952 | Biological process | regulation of protein autophosphorylation |
GO_0046777 | Biological process | protein autophosphorylation |
GO_0051965 | Biological process | positive regulation of synapse assembly |
GO_0031037 | Biological process | myosin II filament disassembly |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0043197 | Cellular component | dendritic spine |
GO_0005829 | Cellular component | cytosol |
GO_0014069 | Cellular component | postsynaptic density |
GO_0005737 | Cellular component | cytoplasm |
GO_0004686 | Molecular function | elongation factor-2 kinase activity |
GO_0008135 | Molecular function | translation factor activity, RNA binding |
GO_0004672 | Molecular function | protein kinase activity |
GO_0005524 | Molecular function | ATP binding |
GO_0005516 | Molecular function | calmodulin binding |
GO_0005509 | Molecular function | calcium ion binding |
Gene name | EEF2K |
Protein name | Eukaryotic elongation factor 2 kinase Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase) Alternative protein EEF2K |
Synonyms | |
Description | FUNCTION: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced. . |
Accessions | O00418 ENST00000568269.5 H3BRH4 ENST00000263026.10 L8E8G5 |