SPTB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051693Biological processactin filament capping
GO_0030036Biological processactin cytoskeleton organization
GO_0098885Biological processmodification of postsynaptic actin cytoskeleton
GO_0098978Cellular componentglutamatergic synapse
GO_0005886Cellular componentplasma membrane
GO_0009898Cellular componentcytoplasmic side of plasma membrane
GO_0032991Cellular componentprotein-containing complex
GO_0098794Cellular componentpostsynapse
GO_0030864Cellular componentcortical actin cytoskeleton
GO_0014731Cellular componentspectrin-associated cytoskeleton
GO_0015629Cellular componentactin cytoskeleton
GO_0005829Cellular componentcytosol
GO_0042995Cellular componentcell projection
GO_0030054Cellular componentcell junction
GO_0008091Cellular componentspectrin
GO_0005200Molecular functionstructural constituent of cytoskeleton
GO_0051015Molecular functionactin filament binding
GO_0030506Molecular functionankyrin binding
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding

IV. Literature review

[source]
Gene nameSPTB
Protein nameBeta-spectrin
Spectrin beta chain
Spectrin beta chain, erythrocytic (Beta-I spectrin)
Spectrin beta, erythrocytic
SynonymsSPTB1
DescriptionFUNCTION: Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane.

AccessionsENST00000553938.5
ENST00000644917.1 [P11277-2]
H0YJE6
B2RMN7
A1YZ73
ENST00000389722.7 [P11277-2]
ENST00000389720.4 [P11277-1]
P11277