Name | Number of supported studies | Average coverage | |
---|---|---|---|
retinal bipolar neuron | 4 studies | 30% ± 9% | |
rod bipolar cell | 3 studies | 51% ± 13% |
Insufficient scRNA-seq data for expression of GABRR1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 37% | 9.31 | 540 / 1445 | 52% | 1.87 | 96 / 183 |
blood vessel | 88% | 110.16 | 1181 / 1335 | 0% | 0 | 0 / 0 |
bladder | 38% | 7.43 | 8 / 21 | 21% | 0.77 | 108 / 504 |
skin | 44% | 8.17 | 794 / 1809 | 11% | 1.23 | 50 / 472 |
muscle | 52% | 9.87 | 420 / 803 | 0% | 0 | 0 / 0 |
lung | 13% | 1.49 | 74 / 578 | 34% | 1.29 | 396 / 1155 |
kidney | 44% | 9.89 | 39 / 89 | 2% | 0.04 | 20 / 901 |
uterus | 24% | 2.38 | 40 / 170 | 18% | 0.88 | 83 / 459 |
prostate | 40% | 5.28 | 98 / 245 | 1% | 0.02 | 4 / 502 |
ovary | 16% | 1.47 | 28 / 180 | 23% | 1.07 | 99 / 430 |
intestine | 20% | 2.31 | 197 / 966 | 13% | 0.47 | 71 / 527 |
breast | 30% | 4.65 | 138 / 459 | 2% | 0.06 | 17 / 1118 |
stomach | 12% | 1.08 | 44 / 359 | 19% | 0.57 | 55 / 286 |
adrenal gland | 20% | 1.88 | 51 / 258 | 3% | 0.05 | 7 / 230 |
tonsil | 0% | 0 | 0 / 0 | 20% | 0.79 | 9 / 45 |
thymus | 18% | 1.86 | 119 / 653 | 1% | 0.02 | 6 / 605 |
brain | 17% | 2.05 | 457 / 2642 | 1% | 0.07 | 10 / 705 |
adipose | 16% | 1.92 | 188 / 1204 | 0% | 0 | 0 / 0 |
spleen | 10% | 0.75 | 24 / 241 | 0% | 0 | 0 / 0 |
pancreas | 3% | 0.24 | 10 / 328 | 7% | 0.15 | 12 / 178 |
heart | 7% | 0.52 | 57 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 6% | 0.34 | 5 / 80 |
liver | 4% | 0.31 | 9 / 226 | 1% | 0.01 | 4 / 406 |
peripheral blood | 2% | 0.18 | 21 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0042391 | Biological process | regulation of membrane potential |
GO_0050804 | Biological process | modulation of chemical synaptic transmission |
GO_0099505 | Biological process | regulation of presynaptic membrane potential |
GO_1902476 | Biological process | chloride transmembrane transport |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0007214 | Biological process | gamma-aminobutyric acid signaling pathway |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_1902495 | Cellular component | transmembrane transporter complex |
GO_0043005 | Cellular component | neuron projection |
GO_0042734 | Cellular component | presynaptic membrane |
GO_0098982 | Cellular component | GABA-ergic synapse |
GO_0034707 | Cellular component | chloride channel complex |
GO_0045202 | Cellular component | synapse |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_1902711 | Cellular component | GABA-A receptor complex |
GO_0019904 | Molecular function | protein domain specific binding |
GO_0044877 | Molecular function | protein-containing complex binding |
GO_0004890 | Molecular function | GABA-A receptor activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0030594 | Molecular function | neurotransmitter receptor activity |
GO_0022851 | Molecular function | GABA-gated chloride ion channel activity |
GO_0099507 | Molecular function | ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential |
GO_0005254 | Molecular function | chloride channel activity |
Gene name | GABRR1 |
Protein name | Gamma-aminobutyric acid receptor subunit rho-1 (GABA(A) receptor subunit rho-1) (GABA(C) receptor) Gamma-aminobutyric acid type A receptor subunit rho1 |
Synonyms | |
Description | FUNCTION: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission. |
Accessions | ENST00000457434.1 ENST00000454853.7 [P24046-1] ENST00000435811.5 [P24046-2] ENST00000369451.7 [P24046-3] F8WB88 P24046 |